SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley +1 more source
CRISPR/Cas9-mediated gene editing in trophoblast cells via mechanoporation for preeclampsia insight. [PDF]
Morshedi Rad D +7 more
europepmc +1 more source
Linacre Institute Paper: Moral and Medical Considerations in the Management of Extrauterine Pregnancy [PDF]
Diamond, Eugene F.
core +2 more sources
Generation of Cloned Sheep Lacking Galactose‐α1,3‐Galactose and N‐Glycolylneuraminic Acid Antigens
ABSTRACT Livestock have long been regarded as a potential source of donor organs to alleviate the global organ shortage for transplantation. Sheep have a similar anatomy to humans, providing the standard model for demonstrating biocompatibility and performance of biological heart valves to obtain regulatory approval for their use in transplantation ...
Sarah J. Appleby +9 more
wiley +1 more source
Effects ofexosome miRNA-369-3p on the biological behavior of trophoblast cells in gestational diabetes. [PDF]
Yang L +5 more
europepmc +1 more source
Co-culture of JEG-3, BeWo and syncBeWo cell lines with adrenal H295R cell line : an alternative model for examining endocrine and metabolic properties of the fetoplacental unit [PDF]
Drwal, Eliza +2 more
core +1 more source
An update on pacemaking in the myometrium
Abstract figure legend The spread of multiple electrical signals (panel A, blue‐to‐red indicates increasing electrical excitability) that are spatiotemporally distinct, yet in‐phase with the excitatory episode, determines action potential shape and form (panel B, as recorded by single cell microelectrodes) and ensures contractile amplitude and duration
Susan Wray, Michael J. Taggart
wiley +1 more source
Immunohistochemical Analysis of IRE1 and PERK Expression in Extravillous Trophoblast Cells of Placenta Accreta Spectrum and Associations With Clinicopathological Parameters. [PDF]
Flindris S +20 more
europepmc +1 more source
Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade +2 more
wiley +1 more source
Human placental trophoblast cells express and secrete basigin via a regulated process of extracellular vesicle release. [PDF]
Nabeel MA +4 more
europepmc +1 more source

