Results 171 to 180 of about 74,627 (274)

SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley   +1 more source

CRISPR/Cas9-mediated gene editing in trophoblast cells via mechanoporation for preeclampsia insight. [PDF]

open access: yesCell Death Dis
Morshedi Rad D   +7 more
europepmc   +1 more source

Generation of Cloned Sheep Lacking Galactose‐α1,3‐Galactose and N‐Glycolylneuraminic Acid Antigens

open access: yesXenotransplantation, Volume 33, Issue 3, May/June 2026.
ABSTRACT Livestock have long been regarded as a potential source of donor organs to alleviate the global organ shortage for transplantation. Sheep have a similar anatomy to humans, providing the standard model for demonstrating biocompatibility and performance of biological heart valves to obtain regulatory approval for their use in transplantation ...
Sarah J. Appleby   +9 more
wiley   +1 more source

An update on pacemaking in the myometrium

open access: yesThe Journal of Physiology, Volume 604, Issue 9, Page 3661-3671, 1 May 2026.
Abstract figure legend The spread of multiple electrical signals (panel A, blue‐to‐red indicates increasing electrical excitability) that are spatiotemporally distinct, yet in‐phase with the excitatory episode, determines action potential shape and form (panel B, as recorded by single cell microelectrodes) and ensures contractile amplitude and duration
Susan Wray, Michael J. Taggart
wiley   +1 more source

Immunohistochemical Analysis of IRE1 and PERK Expression in Extravillous Trophoblast Cells of Placenta Accreta Spectrum and Associations With Clinicopathological Parameters. [PDF]

open access: yesIn Vivo
Flindris S   +20 more
europepmc   +1 more source

Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications

open access: yesThe FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade   +2 more
wiley   +1 more source

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