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Trophoblast Stem Cells

2006
At the first cell fate decision in mammalian development, the origins of trophoblast and embryonic cell lineages are established as the trophectoderm and the inner cell mass (ICM) in the blastocyst. In the trophoblast cell lineage, a subset of the trophectoderm cells maintains the capacity to proliferate and contribute to the extraembryonic ectoderm ...
Mayumi, Oda   +2 more
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Allo‐Antigenicity of Trophoblast Cells*

American Journal of Reproductive Immunology, 1983
ABSTRACT: Trophoblast cells of the placenta represent the frontier of the conceptus at the feto‐maternal interface, exposed to the maternal immune system. The presence or the absence of major histocompatibility (MHC) antigens on trophoblast cells, thus, is a key determinant of immune interactions between the mother and the allogeneic fetus during ...
S, Chatterjee-Hasrouni   +2 more
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Mouse Trophoblast Stem Cells

2005
The trophectoderm is one of the earliest cell types to differentiate in the forming mammalian embryo. It is responsible for the initial implantation and the formation of the trophoblast components of the placenta, an organ essential for nutrient and waste exchange between the fetus and its mother.
Jennifer, Quinn   +2 more
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Microarray Analysis of Trophoblast Cells

2005
A complex repertoire of trophoblast gene products governs the multifaceted functions performed by the placenta during the relatively short period of pregnancy. Cloning and sequencing the human as well as other mammalian genomes allow investigators to gain better insight into the function of trophoblast genes.
Vikram, Budhraja, Yoel, Sadovsky
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Trophoblast stem cells, trophoblast invasion, and organoids – advancements in gynecology

Česká gynekologie
The human placenta serves as a vital barrier between the mother and the developing fetus during pregnancy. A defect in the early development of the placenta is associated with severe pregnancy disorders. Despite its complex development, various molecular processes control placental development, and the specialization of trophoblast cells is still not ...
Petra, Gašparová   +4 more
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Placental Trophoblast Cells

2000
The placenta is essential for implantation of the mammalian embryo into the uterus, protection of the developing fetus from the maternal immune system, establishment of a nutrient/waste exchange system between the maternal and fetal compartments, and production of pregnancy-specific hormones that regulate maternal and fetal physiology.
Veronica Soloveva   +3 more
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Transferrin Expression by Placental Trophoblastic Cells

Placenta, 2004
Transferrin (TF), a 76-80 kDa glycoprotein, is responsible for the transport of iron to cells within both the fetal and maternal systems, but it does not cross the multiple cell layer barrier of the placenta. Recent findings that both rat and human placental cells produce TF indicated that placental TF may function in some manner to transport or ...
R, Morris Buus, F R, Boockfor
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Isolation and Characterization of Rat Trophoblast Cells

American Journal of Reproductive Immunology and Microbiology, 1988
ABSTRACT: Previous immunohistochemical studies of the rat placenta using specific alloantisera and/or monoclonal antibodies showed that the basal zone trophoblasts stained for Pa and Aa class I major histocompatibility complex (MHC) antigens and for the human SP1‐related antigen.
K I, Wang   +4 more
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