Results 111 to 120 of about 21,086 (158)

Immunological regulation of trophoblast invasion

Journal of Reproductive Immunology, 2011
In investigating the immunological regulation of trophoblast invasion, emphasis is frequently placed on the constitution of the implantation site and its specific characteristics. However trophoblast cells are able of invading into not only the uterine tissue, but in the case of ectopic pregnancies also invade into other tissues, where they are ...
Astrid Hammer
exaly   +3 more sources

Quantitative analysis of trophoblast invasion in preeclampsia

Acta Obstetricia Et Gynecologica Scandinavica, 2003
Background.  The process of physiological conversion of spiral arteries is dependent on the invasion of the interstitium and spiral arteries of the uterine wall by invasive extravillous trophoblast thereby creating a high flow–low resistance vessel. Quantitative data on restriction of trophoblast invasion and failure of spiral artery transformation are
Thajasvarie, Naicker, Shaun M, Khedun, Jagidesa, Moodley, Robert, Pijnenborg   +3 more
exaly   +3 more sources

Factors Regulating Trophoblast Invasion

Gynecologic and Obstetric Investigation, 2007
Implantation in the human is unique. This uniqueness is characterized on the maternal side by a spontaneous and massive decidualization of the endometrium and on the embryonic side by an almost unlimited invasive potential. Human embryos express an intrinsic invasive potential, which allows them to implant almost anywhere except in the endometrium ...
Cohen, Marie-Benoîte, Bischof, Paul
openaire   +4 more sources

Trophoblast invasion

Reproductive Medicine Review, 1994
The establishment of a pregnancy depends upon mechanisms of forming close contacts between embryonic/fetal and maternal tissues. The starting point is the attachment of the blastocyst to the uterine wall, and this critical step is followed by a series of different morphogenetic events leading to placentation.
openaire   +1 more source

Expression of DAB2IP in human trophoblast and its role in trophoblast invasion

The Journal of Maternal-Fetal & Neonatal Medicine, 2015
DAB2IP is a growth inhibitor present in many types of cancer cells and is associated with epigenetic regulations controlling tumor development. The primary objective of this study is to determine whether DAB2IP participates in the invasion and migration of trophoblasts during placental development.The expressions of DAB2IP in human placentas (10 villi,
Nan, Shan, Xiaoqiu, Xiao, Ying, Chen, Xin, Luo, Nanlin, Yin, Qinyin, Deng, Hongbo, Qi   +6 more
openaire   +2 more sources

Signal Transduction in Trophoblast Invasion

2005
During the first trimester of pregnancy, well-differentiated primary cells of the placenta known as trophoblast cells grow in an invasive and destructive fashion similar to malignancies, but limited in space and time. The comparison of trophoblast cells with their malignant counterpart, human choriocarcinoma cells, offers an attractive model to ...
Justine S, Fitzgerald, Susann, Busch, Tobias, Wengenmayer, Katharina, Foerster, Torben, de la Motte, Tobias G, Poehlmann, Udo R, Markert   +6 more
openaire   +2 more sources

Biochemistry and Molecular Biology of Trophoblast Invasion

Annals of the New York Academy of Sciences, 2001
AbstractCytotrophoblastic cells (CTBs) from first‐trimester placenta form columns of invasive CTBs. This invasive behavior is due to the ability of CTBs to secrete matrix metalloproteinases (MMPs), since tissue inhibitor of MMPs (TIMP) inhibits their invasiveness in the extracellular space.
Bischof P, Meisser A, Campana A
openaire   +3 more sources

Mechanism of control of trophoblast invasion in situ

Journal of Cellular Physiology, 1991
AbstractWe have previously shown that first trimester human trophoblast cells share in vitro invasive properties with malignant cells. In this study we show that the in situ control of trophoblast invasion is provided by the uterine microenvironment.
C H, Graham, P K, Lala
openaire   +2 more sources

HLA expression by trophoblast of invasive moles

Placenta, 1987
HLA expression by the trophoblast in invasive hydatidiform mole was analysed by immunoperoxidase staining. In the invading villi of an invasive mole, villous trophoblast, both syncytiotrophoblast and cytotrophoblast, failed to show a positive reaction for HLA-A, -B and -C and HLA-DR.
M, Sasagawa, Y, Ohmomo, K, Kanazawa, S, Takeuchi   +3 more
openaire   +2 more sources

Extravillous Trophoblast, Trophoblastic Invasion, and Fibrinoid

2010
The nonvillous parts of the placenta include the chorionic plate, cell islands, cell columns, placental septa, basal plate, marginal zone, and fibrinoid deposits (Fig. 8.1). These structures do not participate in maternofetal exchange, but have mechanical and metabolic functions.
openaire   +1 more source