Results 91 to 100 of about 40,342 (338)

Development of node architecture and emergence of molecular organizer characteristics in the pig embryo

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The avian node is the equivalent of the amphibian Spemann's organizer, as indicated by its ability to induce a secondary axis, cellular contribution, and gene expression, whereas the node of the mouse, which displays limited inductive capacities, was suggested to be a part of spatially distributed signaling.
Braah Harmoush   +2 more
wiley   +1 more source

A network of transient domains for breaking symmetry during anterior–posterior axis formation in the porcine embryo

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Breaking radial symmetry for anterior–posterior axis formation is one of the key developmental steps of vertebrate gastrulation and is established through a succession of transient domains defined by morphology or gene expression. Three such domains were interpreted recently in the rabbit to be part of a “three‐anchor‐point model” for axis ...
Ruben Plöger   +2 more
wiley   +1 more source

Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins.

open access: yesPLoS Neglected Tropical Diseases, 2020
Zika virus (ZIKV) causes congenital Zika syndrome (CZS), which is characterized by fetal demise, microcephaly and other abnormalities. ZIKV in the pregnant woman circulation must cross the placental barrier that includes fetal endothelial cells and ...
Murilo Sena Amaral   +10 more
doaj   +1 more source

The Fetal Allograft Revisited: Does the Study of an Ancient Invertebrate Species Shed Light on the Role of Natural Killer Cells at the Maternal-Fetal Interface? [PDF]

open access: yes, 2008
Human pregnancy poses a fundamental immunological problem because the placenta and fetus are genetically different from the host mother. Classical transplantation theory has not provided a plausible solution to this problem.
Barrier, Breton F.   +3 more
core   +6 more sources

Hypertensive pregnancy disorder, an under‐recognized women specific risk factor for heart failure?

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 3, Page 459-472, March 2025.
Hypertensive disorders of pregnancy as a risk factor for heart failure. BMI, body mass index; CV, cardiovascular; CVD, cardiovascular disease; HELLP, haemolysis, elevated liver enzymes, low platelet count. Abstract During pregnancy, the maternal cardiovascular (CV) system undergoes major haemodynamic alterations ensuring adequate placental perfusion ...
Chahinda Ghossein‐Doha   +4 more
wiley   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang   +11 more
wiley   +1 more source

Stimulation of hCG protein and mRNA in first trimester villous cytotrophoblast cells in vitro by glycodelin A [PDF]

open access: yes, 2005
Aim: Human chorionic gonadotropin (hCG) is produced by fetal trophoblast cells and secreted into maternal circulation mainly in the first trimester of pregnancy.
Albanese   +19 more
core   +1 more source

Evaluating the ability of fullPIERS calculator to predict adverse maternal outcomes in pre‐eclampsia at Charlotte Maxeke Johannesburg Academic Hospital

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the ability of the fullPIERS model to predict adverse maternal outcomes in patients diagnosed as early‐onset pre‐eclampsia at Charlotte Maxeke Johannesburg Academic Hospital, South Africa. Methods Retrospective record review and analysis of 134 patients admitted with early‐onset pre‐eclampsia.
Thomas Matonhodze, Robert Nyakoe
wiley   +1 more source

Gestational diabetes mellitus and vascular malperfusion lesions in the placenta: A systematic review and meta‐analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Gestational diabetes mellitus (GDM) can result in increased placental lesions related to high maternal blood glucose, but these relationships are not well understood. Objective To examine the relationship between GDM and placental vascular malperfusion lesions: accelerated villous maturation, increased syncytial knots, delayed ...
Amrita Arcot   +4 more
wiley   +1 more source

Decidual Macrophages Are Significantly Increased in Spontaneous Miscarriages and Over-Express FasL [PDF]

open access: yes, 2012
Decidual macrophages (DM) are the second most abundant population in the fetal-maternal interface. Their role has been so far identified as being local immuno-modulators favoring the maternal tolerance to the fetus.
Angioni   +41 more
core   +2 more sources

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