Results 71 to 80 of about 30,805 (282)

Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy. [PDF]

, 2010
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Brosnihan, KB, Cartwright, JE, Dechend, R, Geusens, N, Hering, L, Herse, F, Huppertz, B, Luft, FC, Muller, DN, Pijnenborg, R, Staff, AC, Verlohren, S, Wenzel, K   +12 more
core   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source

VEGF deprivation affects endoglin expression in trophoblast cells and natural killers

Медицинская иммунология
Vascular Endothelial Growth Factors (VEGFs) are a group of proteins involved in differentiation of various cell types including endothelial cells, monocytes, macrophages, stem cells, tumor cells, vascular smooth muscle cells, trophoblast cells, and other
E. V. Tyshchuk, E. A. Denisova, O. B. Marko, I. Yu. Kogan, S. A. Selkov, D. I. Sokolov   +5 more
doaj   +1 more source

RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta

Cells, 2019
Preeclampsia (PE) remains a leading cause of maternal and perinatal mortality and morbidity worldwide. Its pathogenesis has not been fully elucidated and no causal therapy is currently available.
Julia Maria Wildner, Alexandra Friemel, Lukas Jennewein, Susanne Roth, Andreas Ritter, Cornelia Schüttler, Qi Chen, Frank Louwen, Juping Yuan, Nina-Naomi Kreis   +9 more
doaj   +1 more source

Obstetric anti-phospholipid syndrome: from pathogenesis to treatment

Immunological Medicine, 2021
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by clinical manifestations such as thrombosis and obstetric complications with documented persistence of antiphospholipid antibodies (aPLs).
Kayoko Kaneko, Nobuaki Ozawa, Atsuko Murashima   +2 more
doaj   +1 more source

Expression and importance of matrix metalloproteinase 2 and 9 (MMP-2 and -9) in human trophoblast invasion [PDF]

, 2004
Background The aim of this study was to examine the invasiveness of first trimester trophoblasts according to the secretion profile of MMP-2 and -9 at different gestational stages, and to test the similarity between primary trophoblast cell-culture and ...
Gabarin Diana, Goldman Shlomit, Staun-Ram Elsebeth, Shalev Eliezer   +3 more
core   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Bradykinin Sequestration by Plasmodium berghei Infected Erythrocytes Conditions B2R Signaling and Parasite Uptake by Fetal Trophoblasts

Frontiers in Microbiology, 2018
Plasmodium infection during pregnancy causes placental malfunction reducing fetus sustainability and leading to abortions, stillbirths, low birth weight or premature delivery.
Luciana Vieira de Moraes, André Barateiro, Patrícia Marques Sousa, Carlos Penha-Gonçalves   +3 more
doaj   +1 more source

N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro [PDF]

, 2004
Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects.
Briese, V., Friese, K., Gundel, G., Jeschke, U., Mylonas, I., Müller, H., Richter, D.-U., Streu, A., Unverzagt, C.   +8 more
core   +1 more source

Impact of donor mare and stallion identity on the likelihood of pregnancy after transfer of in vitro produced embryos

Equine Veterinary Journal, EarlyView.
Abstract Background The success of in vitro embryo production (IVEP) is influenced by donor mare and stallion. Objectives To determine whether donor mare and stallion influence the pregnancy rate after transfer of in vitro produced (IVP) blastocysts and to identify factors influencing the likelihood of obtaining one or more pregnancies from a single ...
M. Papas, T. A. E. Stout, J. C. M. Vernooij, B. Leemans, L. Arnold, M. M. Beitsma, L. I. Wijnands, M. de Ruijter‐Villani, S. Colleoni, G. Lazzari, C. Galli, A. Claes   +11 more
wiley   +1 more source