Results 61 to 70 of about 21,207 (299)

Obstetric anti-phospholipid syndrome: from pathogenesis to treatment

Immunological Medicine, 2021
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by clinical manifestations such as thrombosis and obstetric complications with documented persistence of antiphospholipid antibodies (aPLs).
Kayoko Kaneko, Nobuaki Ozawa, Atsuko Murashima   +2 more
doaj   +1 more source

106. IL-6 INCREASES THE SHEDDING OF NECROTIC TROPHOBLASTS FROM PLACENTAL EXPLANTS

, 2009
Preeclampsia (PE) is characterised by elevated maternal blood pressure, preceded by endothelial cell dysfunction. Dead trophoblasts, shed from the placenta may be one of the factors that trigger PE.
B. Liu, L. W. Chamley, L. Chen, P. R. Stone, Q. Chen, H. Zhao   +5 more
core   +1 more source

Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins.

, 2020
Zika virus (ZIKV) causes congenital Zika syndrome (CZS), which is characterized by fetal demise, microcephaly and other abnormalities. ZIKV in the pregnant woman circulation must cross the placental barrier that includes fetal endothelial cells and ...
Murilo Sena Amaral, Giovanna Gonçalves de Oliveira Olberg, Roselane Paiva Gomes, Sergio Verjovski-Almeida, Luiz Carlos Caires-Júnior, Alessandra Soares-Schanoski, Mayana Zatz, Renato Mancini Astray, Ernesto Goulart, David Abraham Morales-Vicente, Jorge E Kalil   +10 more
core   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

VEGF deprivation affects endoglin expression in trophoblast cells and natural killers

Медицинская иммунология
Vascular Endothelial Growth Factors (VEGFs) are a group of proteins involved in differentiation of various cell types including endothelial cells, monocytes, macrophages, stem cells, tumor cells, vascular smooth muscle cells, trophoblast cells, and other
E. V. Tyshchuk, E. A. Denisova, O. B. Marko, I. Yu. Kogan, S. A. Selkov, D. I. Sokolov   +5 more
doaj   +1 more source

RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta

Cells, 2019
Preeclampsia (PE) remains a leading cause of maternal and perinatal mortality and morbidity worldwide. Its pathogenesis has not been fully elucidated and no causal therapy is currently available.
Julia Maria Wildner, Alexandra Friemel, Lukas Jennewein, Susanne Roth, Andreas Ritter, Cornelia Schüttler, Qi Chen, Frank Louwen, Juping Yuan, Nina-Naomi Kreis   +9 more
doaj   +1 more source

Annexin-A5 promotes membrane resealing in human trophoblasts

, 2015
Annexin-A5 (AnxA5) is the smallest member of the annexins, a group of soluble proteins that bind to membranes containing negatively-charged phospholipids, principally phosphatidylserine, in a Ca2+-dependent manner.
DEGRELLE, S. A., CARMEILLE, R., Carmeille, Romain, Gounou, Céline, Degrelle, Severine,, Brisson, Alain R., Brisson, Alain, Plawinski, Laurent, Bouvet, Flora, Evain-Brion, Danièle, Degrelle, Severine, S., Degrelle, Séverine A., EVAIN-BRION, D., Bouter, Anthony   +13 more
core   +1 more source

Impact of donor mare and stallion identity on the likelihood of pregnancy after transfer of in vitro produced embryos

Equine Veterinary Journal, EarlyView.
Abstract Background The success of in vitro embryo production (IVEP) is influenced by donor mare and stallion. Objectives To determine whether donor mare and stallion influence the pregnancy rate after transfer of in vitro produced (IVP) blastocysts and to identify factors influencing the likelihood of obtaining one or more pregnancies from a single ...
M. Papas, T. A. E. Stout, J. C. M. Vernooij, B. Leemans, L. Arnold, M. M. Beitsma, L. I. Wijnands, M. de Ruijter‐Villani, S. Colleoni, G. Lazzari, C. Galli, A. Claes   +11 more
wiley   +1 more source

Bradykinin Sequestration by Plasmodium berghei Infected Erythrocytes Conditions B2R Signaling and Parasite Uptake by Fetal Trophoblasts

Frontiers in Microbiology, 2018
Plasmodium infection during pregnancy causes placental malfunction reducing fetus sustainability and leading to abortions, stillbirths, low birth weight or premature delivery.
Luciana Vieira de Moraes, André Barateiro, Patrícia Marques Sousa, Carlos Penha-Gonçalves   +3 more
doaj   +1 more source

Invasive trophoblasts stimulate vascular smooth muscle cell apoptosis by a Fas ligand-dependent mechanism

, 2006
During pregnancy, trophoblasts migrate from the placenta into uterine spiral arteries, transforming them into wide channels that lack vasoconstrictive properties. In pathological pregnancies, this process is incomplete.
Cartwright, JE, Aplin, JD, Whitley, GS, Keogh, Rosemary J., Harris, Lynda K.; id_orcid, Keogh, RJ, Harris, LK, Baker, PN, Aplin, John D.; id_orcid, Whitley, GSJ, Whitley, Guy St J, Baker, Philip N., Cartwright, Judith E., Wareing, M, Wareing, Mark   +14 more
core   +1 more source