Results 91 to 100 of about 18,040 (249)

Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register‐based cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Active surveillance for cervical intraepithelial neoplasia grade 2 is not associated with increased risks of adverse pregnancy outcomes compared to large loop excision of the transformation zone. Abstract Introduction Previous studies have suggested that human papillomavirus (HPV) and HPV‐related disease may be associated with increased risk of adverse
Kirstine Kold Katholm   +6 more
wiley   +1 more source

Antígenos de histocompatibilidad HLA-G y embarazo HLA-G histocompatibility antigens related to pregnancy

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2010
El componente HLA-G es una molécula clase I no clásica (Ib) del sistema principal de histocompatibilidad. Esta adopta 7 isoformas como resultado del empalme alternativo de un mismo RNA inmaduro; 4 se encuentran ligadas con la membrana (HLA-G1-G2-G3-G4) y
Luz M Morera Barrios   +5 more
doaj  

Prophylactic ureteral stent placement for the prevention of urinary tract injuries in women with placenta accreta spectrum undergoing peripartum cesarean hysterectomy: A retrospective cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Prophylactic ureteral stent placement was associated with a reduced risk of urinary tract injury in women with placenta accreta spectrum undergoing peripartum cesarean hysterectomy, independent of prior cesarean number. Abstract Introduction This retrospective cohort study investigated whether preoperative bilateral ureteral stent placement reduces ...
Hasan Berkan Sayal   +5 more
wiley   +1 more source

Longitudinal circulating tumour DNA identifies patients at high risk of upstaging and recurrence in non‐muscle‐invasive bladder cancer

open access: yesBJU International, EarlyView.
Objectives To evaluate whether longitudinal tumour‐informed circulating tumour DNA (ctDNA) testing identifies patients at increased risk of upstaging and recurrence in high‐risk non‐muscle‐invasive bladder cancer (NMIBC). Patients and Methods A cohort of 52 patients with high‐risk NMIBC underwent serial plasma ctDNA testing using a personalised tumour ...
Can Aydogdu   +17 more
wiley   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

open access: yesCell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang   +11 more
wiley   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

open access: yesCell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du   +7 more
wiley   +1 more source

Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures

open access: yesClinical & Translational Immunology
Objectives Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) virus infection in pregnancy is associated with higher incidence of placental dysfunction, referred to by a few studies as a ‘preeclampsia‐like syndrome’.
Nataly Stylianou   +27 more
doaj   +1 more source

Targeting oxidative stress in preeclampsia

open access: yesHypertension in Pregnancy
Preeclampsia is a complex condition characterized by elevated blood pressure and organ damage involving kidneys or liver, resulting in significant morbidity and mortality for both the mother and the fetus.
Dinara Afrose   +2 more
doaj   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

open access: yesCell Proliferation, EarlyView.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik   +10 more
wiley   +1 more source

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