Results 191 to 200 of about 43,593 (324)

Pre-eclampsia-related TLR2/4 signaling activates NOX2/4 to induce oxidative stress and ferroptosis in trophoblasts. [PDF]

Eur J Med Res
Zhang Y, Ke Y, Zhu B, Chen Z, Ren L, Zhang J, Wu J.   +6 more
europepmc   +1 more source

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice [PDF]

, 2017
Aagaard, Barrows, Bayer, Bin Cao, Cadwell, Cao, Cao, Cao-Lormeau, Cemma, Chibueze, Chiramel, Delorme-Axford, Delvecchio, El Costa, Elfiky, Eyer, Farias, Hamel, Indira U. Mysorekar, Jurado, Kaplan, Khan, Klionsky, Lamont, Lennemann, Levine, Liang, Lindsay A. Parnell, Martín-Acebes, Mateo, Michael S. Diamond, Miner, Mysorekar, Pirooz, Quicke, Rosenfeldt, Rossant, Sacramento, Savarino, Sharma, Shoji-Kawata, Signorelli, Tabata, Tricou, Vandergaast, Vermillion, Wenzel, Xu, Yockey, Zmurko   +49 more
core   +2 more sources

Exosomal circDNAJB6 derived from decidual macrophages promotes preeclampsia progression via the miR-670-5p/TOB2 axis and by subsequently regulating the PPARγ/NF-κB pathway. [PDF]

J Transl Med
Zhang L, Tian X, Liu M, Zong H, Yu W, Zheng C, Zhang D, Zhang H.   +7 more
europepmc   +1 more source

Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast

The Journal of Physiology, EarlyView.
Abstract figure legend The human placenta not only detects the presence of Pb and Cd but also carries hypoxia and inflammatory risks, which are associated with pregnancy complications. To understand the impact of these factors on the placental trophoblast, we evaluated the effect of Pb and Cd on mitochondrial function and the NLRP3 inflammasome in ...
Yifeng Dai, Xijin Xu, Xia Huo, Joost H. N. Schuitemaker, Marijke M. Faas   +4 more
wiley   +1 more source

Altered AADAC Modulates Trophoblast Invasion and Suggests a Potential Angiogenic Regulatory Role in Severe Preeclampsia. [PDF]

Int J Mol Sci
An HJ, Song DH, Kim YM, Jo HC, Baek JC, Yang J, Park JE.   +6 more
europepmc   +1 more source

Benzopyrene and Experimental Stressors Cause Compensatory Differentiation in Placental Trophoblast Stem Cells

, 2010
Daniel A. Rappolee, Awoniyi O. Awonuga, Elizabeth E. Puscheck, Sichang Zhou, Yufen Xie   +4 more
openalex   +2 more sources

Screening for down syndrome using trophoblast retrieval and isolation of the cervix: preliminary study

, 2020
Min Jin Lee, Soo Hyun Kim, Hee Jin Park, Sung Han Shim, Hee Yeon Jang, Dong Hyun   +5 more
openalex   +2 more sources

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source

The Placenta as an Immunological Environment. [PDF]

Br J Biomed Sci
Menzies FM.
europepmc   +1 more source