Generation of Cloned Sheep Lacking Galactose‐α1,3‐Galactose and N‐Glycolylneuraminic Acid Antigens
ABSTRACT Livestock have long been regarded as a potential source of donor organs to alleviate the global organ shortage for transplantation. Sheep have a similar anatomy to humans, providing the standard model for demonstrating biocompatibility and performance of biological heart valves to obtain regulatory approval for their use in transplantation ...
Sarah J. Appleby +9 more
wiley +1 more source
TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1. [PDF]
Jiang N +12 more
europepmc +1 more source
An update on pacemaking in the myometrium
Abstract figure legend The spread of multiple electrical signals (panel A, blue‐to‐red indicates increasing electrical excitability) that are spatiotemporally distinct, yet in‐phase with the excitatory episode, determines action potential shape and form (panel B, as recorded by single cell microelectrodes) and ensures contractile amplitude and duration
Susan Wray, Michael J. Taggart
wiley +1 more source
Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1<sup>+</sup>PMN-MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age. [PDF]
Chen M +12 more
europepmc +1 more source
Gestational Trophoblastic Neoplasia [PDF]
openaire +2 more sources
Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade +2 more
wiley +1 more source
Trophoblast invasion biology: from normal implantation to accreta spectrum and choriocarcinoma. [PDF]
Mangla M, Motwani R, Palo S, Setty A.
europepmc +1 more source
The Critical Role of GALNTs‐Regulated O‐GalNAc Glycosylation in Cancer Malignancy
The GALNT family initiates mucin‐type O‐GalNAc glycosylation in the Golgi apparatus and how regulatory mechanisms, including GALNT relocalization and microRNA control, modulate this process. Dysregulated O‐GalNAc glycosylation alters key cellular behaviors and promotes cancer malignancy, highlighting its relevance to tumor progression as well as its ...
Jiahao Liu +7 more
wiley +1 more source
CD147: a critical factor in normal and pathological pregnancies. [PDF]
Sun H, Gao J, Yang S, Yao X.
europepmc +1 more source

