Stillbirth in pregnancies with flat OGTT: Placental clues to occult maternal dysmetabolism
International Journal of Gynecology &Obstetrics, Volume 173, Issue 2, Page 1133-1138, May 2026.
Emma Bertucci +10 more
wiley +1 more source
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo +6 more
wiley +1 more source
Beyond traditional models: microfluidic technologies for engineering the human placenta <i>in vitro</i>. [PDF]
Masserdotti A +9 more
europepmc +1 more source
Defining the tumor microenvironment of non‐small cell lung cancer
The tumor microenvironment (TME) in non‐small cell lung cancer is highly heterogeneous, both at a patient level and tumor microenvironment resolution. Defining the tumor microenvironment from patient‐responders and non‐responders will aid in the development of targeted therapeutics specific for each individual patient.
Kidane Siele Embaye +5 more
wiley +1 more source
New PPARG Exons: Cell-Specific Expression of Their RNAs in the Human Placenta. [PDF]
Vignaud ML, Morin N, Fournier T.
europepmc +1 more source
MicroRNA-20b and ERK1/2 pathway independently regulate the expression of tissue factor in hematopoietic and trophoblastic differentiation of human embryonic stem cells [PDF]
core +1 more source
ABSTRACT Preeclampsia is a severe gestational complication whose molecular pathogenesis remains poorly understood despite extensive research. It is now recognized that both maternal and fetal cells contribute to disease progression. Notably, single‐cell RNA sequencing of cord blood cells from preeclamptic pregnancies has not been previously ...
Polina Vishnyakova +14 more
wiley +1 more source
HIF-1α mediated placental ischemic signaling in the development of early-onset preeclampsia. [PDF]
You K +5 more
europepmc +1 more source
SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley +1 more source
Exosomal circDNAJB6 derived from decidual macrophages promotes preeclampsia progression via the miR-670-5p/TOB2 axis and by subsequently regulating the PPARγ/NF-κB pathway. [PDF]
Zhang L +7 more
europepmc +1 more source

