Inhibition of RIPK1/RIPK3-MLKL inflammatory signaling pathway activation attenuates preterm birth. [PDF]
Bing X +6 more
europepmc +1 more source
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed +10 more
wiley +1 more source
HIF2α-induced lysyl oxidase safeguards successful pregnancy by remodelling collagens at the feto-maternal interface. [PDF]
Aikawa S +13 more
europepmc +1 more source
Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang +8 more
wiley +1 more source
Recent insights into the immunobiology of congenital cytomegalovirus infection. [PDF]
Enninga EAL, Schleiss MR, Bierle CJ.
europepmc +1 more source
Practice‐Changing Advances in Systemic Therapies Shaping the Landscape of Lung Cancer in 2025
This review synthesizes 2025 breakthroughs in systemic therapies of lung cancer, especially in targeted and immunotherapies, accelerating mortality decline across non‐small cell lung cancer and small cell lung cancer stages. ABSTRACT With the rapid advancement of molecular profiling and precision therapeutics, targeted and immunotherapeutic strategies ...
Zhenyu Zhou +3 more
wiley +1 more source
Semaglutide Induces Oxidative Stress and Differentially Modulates mTOR-Dependent Growth and Invasion in Human Trophoblast Cell Models: Implications for Placental Function. [PDF]
Thurmond E +7 more
europepmc +1 more source
Treatment Advances in Gynecologic Cancers: Insights From Recent Clinical Trials
Overview of immunotherapy and antibody‐drug conjugates, and their mechanism against cancer. (The Graphical Abstract Image was created with BioRender.) ABSTRACT Gynecologic cancers remain a major global health burden for women. Their management has evolved toward a gynecologic oncologist‐led multimodal paradigm.
Yiyang Shen +6 more
wiley +1 more source
SIRT1-NCOR2 Corepressor Modulates Trophoblast-Macrophage Interactions in Preeclampsia. [PDF]
Liu Z +8 more
europepmc +1 more source

