Results 41 to 50 of about 43,593 (324)

Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]

open access: yes, 1989
Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY   +7 more
core   +3 more sources

Functional Analysis of p21Cip1/CDKN1A and Its Family Members in Trophoblastic Cells of the Placenta and Its Roles in Preeclampsia

open access: yesCells, 2021
Preeclampsia (PE), a gestational hypertensive disease originating from the placenta, is characterized by an imbalance of various cellular processes.
Nina-Naomi Kreis   +7 more
doaj   +1 more source

Fetal-derived trophoblast use the apoptotic cytokine tumor necrosis factor-alpha-related apoptosis-inducing ligand to induce smooth muscle cell death. [PDF]

open access: yes, 2007
Remodeling of the uterine spiral arteries during pregnancy transforms them from high to low resistance vessels that lack vasoconstrictive properties. This process is essential to meet the demand for increased blood flow imposed by the growing fetus. Loss
Aplin, JD   +6 more
core   +1 more source

Placental syncytiotrophoblast constitutes a major barrier to vertical transmission of Listeria monocytogenes. [PDF]

open access: yes, 2010
Listeria monocytogenes is an important cause of maternal-fetal infections and serves as a model organism to study these important but poorly understood events. L.
A Beham   +82 more
core   +3 more sources

Red fruit oil increases trophoblast cells and decreases caspase-9 expression in placenta of lead exposed mice

open access: yesUniversa Medicina, 2016
BACKGROUND Lead is able to pass through the placental barrier and interfere with fetal development. Red fruit has high antioxidant activity, due to carotenoids (pro-vitamin A), tocopherols (vitamin E) and unsaturated fatty acids.
Portia Sumarsono   +2 more
doaj   +1 more source

Downregulation of Transcriptional Activity, Increased Inflammation, and Damage in the Placenta Following in utero Zika Virus Infection Is Associated With Adverse Pregnancy Outcomes

open access: yesFrontiers in Virology, 2022
Zika virus (ZIKV) infection during pregnancy causes serious adverse outcomes to the developing fetus, including fetal loss and birth defects known as congenital Zika syndrome (CZS). The mechanism by which ZIKV infection causes these adverse outcomes, and
Patrick S. Creisher   +11 more
doaj   +1 more source

Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities. [PDF]

open access: yes, 2018
During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly shown to cause fetal loss and congenital malformations in acutely and chronically infected pregnant women.
Aagaard, Kjersti M   +17 more
core   +2 more sources

Myelin Oligodendrocyte Glycoprotein-Independent Rubella Infection of Keratinocytes and Resistance of First-Trimester Trophoblast Cells to Rubella Virus In Vitro

open access: yesViruses, 2018
Rubella virus (RuV), which belongs to the family Togaviridae and genus Rubivirus, causes systemic infection in children and young adults and congenital rubella syndrome in developing fetuses if the infection occurs during pregnancy.
Quang Duy Trinh   +4 more
doaj   +1 more source

Estrogen Actions in Placental Vascular Morphogenesis and Spiral Artery Remodeling: A Comparative View between Humans and Mice

open access: yesCells, 2023
Estrogens, mainly 17β-estradiol (E2), play a critical role in reproductive organogenesis, ovulation, and fertility via estrogen receptors. E2 is also a well-known regulator of utero-placental vascular development and blood-flow dynamics throughout ...
Mariam Rusidzé   +8 more
doaj   +1 more source

From Coxiella burnetii Infection to Pregnancy Complications: Key Role of the Immune Response of Placental Cells

open access: yesPathogens, 2021
The infection of pregnant animals and women by Coxiella burnetii, an intracellular bacterium, compromises both maternal health and foetal development. The placenta is targeted by C.
Sandra Madariaga Zarza   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy