Results 41 to 50 of about 40,342 (338)

Dysfunction of CCR1+ decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss

open access: yesFrontiers in Immunology, 2022
Recurrent pregnancy loss (RPL) puzzles 1–3% of women of childbearing age worldwide. Immunological factors account for more than 60% of cases of unexplained RPL (URPL); however, the underlying mechanism remains unclear.
Yifei Sang   +13 more
doaj   +1 more source

Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]

open access: yes, 2004
Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Annett Streu   +24 more
core   +1 more source

First report of caprine abortions due to Chlamydia abortus in Argentina. [PDF]

open access: yes, 2019
Infectious abortions of goats in Argentina are mainly associated with brucellosis and toxoplasmosis. In this paper, we describe an abortion outbreak in goats caused by Chlamydia abortus. Seventy out of 400 goats aborted.
Alvarado Pinedo, María F   +5 more
core   +3 more sources

A generalized linear model for decomposing cis-regulatory, parent-of-origin, and maternal effects on allele-specific gene expression [PDF]

open access: yes, 2017
Joint quantification of genetic and epigenetic effects on gene expression is important for understanding the establishment of complex gene regulation systems in living organisms. In particular, genomic imprinting and maternal effects play important roles in the developmental process of mammals and flowering plants.
arxiv   +1 more source

VEGF DEPRIVATION AFFECTS ENDOGLIN EXPRESSION IN TROPHOBLAST CELLS AND NATURAL KILLERS

open access: yesМедицинская иммунология, 2019
Vascular Endothelial Growth Factors (VEGFs) are a group of proteins that involved in the development of various cell types, including endothelial cells, monocytes, macrophages, stem cells, tumor cells, vascular smooth muscle cells, trophoblast cells, and
Elizaveta Vladimirovna Tyshchuk   +5 more
doaj   +1 more source

Ezrin and Its Phosphorylated Thr567 Form Are Key Regulators of Human Extravillous Trophoblast Motility and Invasion

open access: yesCells, 2023
The protein ezrin has been shown to enhance cancer cell motility and invasion leading to malignant behaviours in solid tumours, but a similar regulatory function in the early physiological reproduction state is, however, much less clear.
Maral E. A. Tabrizi   +2 more
doaj   +1 more source

Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]

open access: yes, 2010
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Cartwright, JE   +12 more
core   +1 more source

Decidual Vasculopathy in Preeclampsia and Spiral Artery Remodeling Revisited: Shallow Invasion versus Failure of Involution

open access: yesAmerican Journal of Perinatology Reports, 2018
Decidual vasculopathy is commonly associated with preeclampsia and develops in the late pregnancy in the uterine spiral arteries, which were previously remodeled by the extravillous trophoblasts.
Peilin Zhang
doaj   +1 more source

TMBIM4 Deficiency Facilitates NLRP3 Inflammasome Activation-Induced Pyroptosis of Trophoblasts: A Potential Pathogenesis of Preeclampsia

open access: yesBiology, 2023
Impaired invasion of EVTs results in inadequate remodelling of arteries and poor placentation, leading to PE. TMBIM4 was found to promote the migration and invasion of human osteosarcoma U2-OS and breast cancer MCF7 cell lines.
Yuanyao Chen   +9 more
doaj   +1 more source

Impaired decidual natural killer cell regulation of vascular remodelling in early human pregnancies with high uterine artery resistance [PDF]

open access: yes, 2012
During human pregnancy, natural killer (NK) cells accumulate in the maternal decidua, but their specific roles remain to be determined. Decidual NK (dNK) cells are present during trophoblast invasion and uterine spiral artery remodelling.
Cartwright, JE   +6 more
core   +1 more source

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