Results 21 to 30 of about 18,040 (249)

Chorion laeve trophoblasts of preeclamptic fetal membranes: histochemically detectable enzyme activities do not change at a subcellular level

open access: yesEuropean Journal of Histochemistry, 2009
We examined the subcellular localization of ADPdegrading activity and cytochrome c oxidase (CCO) activity in chorion laeve trophoblasts from term and near term human fetal membranes, and compared them with those from severe preeclamptic fetal membranes ...
S Matsubara   +5 more
doaj   +1 more source

Interferon gamma is involved in apoptosis of trophoblast cells at the maternal–fetal interface following Toxoplasma gondii infection

open access: yesInternational Journal of Infectious Diseases, 2015
Objective: To assess whether interferon gamma (IFN-γ) secreted by decidual natural killer (dNK) cells at the maternal–fetal interface is involved in the apoptosis of trophoblast cells (trophoblasts) following Toxoplasma gondii infection.
Ling Zhang   +8 more
doaj   +1 more source

TMBIM4 Deficiency Facilitates NLRP3 Inflammasome Activation-Induced Pyroptosis of Trophoblasts: A Potential Pathogenesis of Preeclampsia

open access: yesBiology, 2023
Impaired invasion of EVTs results in inadequate remodelling of arteries and poor placentation, leading to PE. TMBIM4 was found to promote the migration and invasion of human osteosarcoma U2-OS and breast cancer MCF7 cell lines.
Yuanyao Chen   +9 more
doaj   +1 more source

Regulation of trophoblast beta1-integrin expression by contact with endothelial cells

open access: yesCell Communication and Signaling, 2004
Background In human and non-human primates, migratory trophoblasts penetrate the uterine epithelium, invade uterine matrix, and enter the uterine vasculature. Invasive trophoblasts show increased expression of β1 integrin.
Thirkill Twanda L   +5 more
doaj   +1 more source

Factors associated with gestational trophoblastic disease at the Hipólito Unánue Hospital during the period from January 2014 to December 2018

open access: yesRevista de la Facultad de Medicina Humana, 2020
Objective: To determine the risk factors associated with gestational trophoblastic disease in patients treated in an outpatient office of the Gynecobstetrics service of the National Hospital Hipólito Unanue between January 2014 and December 2018. Methods:
Johana Huanca-Llamo   +2 more
doaj   +1 more source

Dysfunction of CCR1+ decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss

open access: yesFrontiers in Immunology, 2022
Recurrent pregnancy loss (RPL) puzzles 1–3% of women of childbearing age worldwide. Immunological factors account for more than 60% of cases of unexplained RPL (URPL); however, the underlying mechanism remains unclear.
Yifei Sang   +13 more
doaj   +1 more source

RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta

open access: yesCells, 2019
Preeclampsia (PE) remains a leading cause of maternal and perinatal mortality and morbidity worldwide. Its pathogenesis has not been fully elucidated and no causal therapy is currently available.
Julia Maria Wildner   +9 more
doaj   +1 more source

Here and there a trophoblast, a transcriptional evaluation of trophoblast cell models

open access: yesCellular and Molecular Life Sciences, 2022
Abstract A recent explosion of methods to produce human trophoblasts and stem cells (hTSC) is fuelling a renewed interest in this tissue. The trophoblast is critical to reproduction by facilitating implantation, maternal physiological adaptations to pregnancy and the growth of the fetus through transport of nutrients between the mother and ...
Brian Joseph Cox, Kendra Naismith
openaire   +2 more sources

Bradykinin Sequestration by Plasmodium berghei Infected Erythrocytes Conditions B2R Signaling and Parasite Uptake by Fetal Trophoblasts

open access: yesFrontiers in Microbiology, 2018
Plasmodium infection during pregnancy causes placental malfunction reducing fetus sustainability and leading to abortions, stillbirths, low birth weight or premature delivery.
Luciana Vieira de Moraes   +3 more
doaj   +1 more source

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