Results 21 to 30 of about 21,207 (299)

Factors associated with gestational trophoblastic disease at the Hipólito Unánue Hospital during the period from January 2014 to December 2018

Revista de la Facultad de Medicina Humana, 2020
Objective: To determine the risk factors associated with gestational trophoblastic disease in patients treated in an outpatient office of the Gynecobstetrics service of the National Hospital Hipólito Unanue between January 2014 and December 2018. Methods:
Johana Huanca-Llamo, German Aranzabal-Alegria, Willer Chanduví   +2 more
doaj   +1 more source

Dysfunction of CCR1+ decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss

Frontiers in Immunology, 2022
Recurrent pregnancy loss (RPL) puzzles 1–3% of women of childbearing age worldwide. Immunological factors account for more than 60% of cases of unexplained RPL (URPL); however, the underlying mechanism remains unclear.
Yifei Sang, Yifei Sang, Yanhong Li, Yanhong Li, Ling Xu, Ling Xu, Jiajia Chen, Jiajia Chen, Dajin Li, Dajin Li, Meirong Du, Meirong Du, Meirong Du, Meirong Du   +13 more
doaj   +1 more source

Investigation into the Role of Forkhead Box A1 (FOXA1) in Late-Onset Preeclampsia of a Prospective Cohort Study and Its Actions on Trophoblast Invasion and Migration

Clinical and Experimental Obstetrics & Gynecology, 2023
Background: The primary objective was to investigate how Forkhead Box A1 (FOXA1) contributes to late-onset preeclampsia (LOPE) and its impact on trophoblast invasion and migration.
Juan Zhu, Yunjian Wei, Zhen Wang, Qiuling Jie, Ping Long, Huamei Yang, Hui Ke, Zaijia Yang, Yanlin Ma   +8 more
doaj   +1 more source

Functional Toll-like receptors in primary first-trimester trophoblasts [PDF]

, 2014
Toll-like receptors (TLRs) are an important part of the body's danger response system and crucial for initiating inflammation in response to cellular stress, tissue damage, and infections.
Vikdal, Anne Jorunn, Tangerås, Line, Gundersen, Astrid, Myklebost, Merete, Austgulen, Rigmor, Stødle, Guro, Olsen, Guro Dalheim, Langaas, Mette, Steinkjer, Bjørg, Ryan, Liv, Iversen, Ann-Charlotte, Leknes, Ann-Helen, Skei, Bente   +12 more
core   +2 more sources

Progesterone Induces Apoptosis and Steroidogenesis in Porcine Placental Trophoblasts

, 2022
Placentation and placental steroidogenesis are important for pregnancy and maternal–fetal health. As pregnancy progresses, the main site of progesterone (P4) synthesis changes from the corpus luteum to the placenta, in which placental trophoblasts ...
Yan Liu, Xin Cao, Liu, Yan, Ding, Hongxiang, Yueshuai Liu, Yang, Yuze, Yuze Yang, Cao, Xin, Hongxiang Ding, Tao Feng, Liu, Yueshuai, Feng, Tao   +11 more
core   +1 more source

Functional Analysis of p21^Cip1/CDKN1A and Its Family Members in Trophoblastic Cells of the Placenta and Its Roles in Preeclampsia

Cells, 2021
Preeclampsia (PE), a gestational hypertensive disease originating from the placenta, is characterized by an imbalance of various cellular processes.
Nina-Naomi Kreis, Alexandra Friemel, Lukas Jennewein, Samira Catharina Hoock, Anna Elisabeth Hentrich, Thorsten Nowak, Frank Louwen, Juping Yuan   +7 more
doaj   +1 more source

Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2

Frontiers in Cell and Developmental Biology, 2020
Human amnion-derived mesenchymal stem cells (AD-MSCs) have been reported as a promising effective treatment to repair tissue. Trophoblast dysfunction during pregnancy is significantly involved in the pathogenesis of preeclampsia (PE).
Yijing Chu, Weiping Chen, Wei Peng, Yong Liu, Lin Xu, Jianxin Zuo, Jun Zhou, Yan Zhang, Ning Zhang, Jing Li, Ling Liu, Ke Yao, Guoqiang Gao, Xiaofei Wang, Rendong Han, Chong Liu, Yan Li, Huansheng Zhou, Yuxiang Huang, Yuanhua Ye   +19 more
doaj   +1 more source

Downregulation of Transcriptional Activity, Increased Inflammation, and Damage in the Placenta Following in utero Zika Virus Infection Is Associated With Adverse Pregnancy Outcomes

Frontiers in Virology, 2022
Zika virus (ZIKV) infection during pregnancy causes serious adverse outcomes to the developing fetus, including fetal loss and birth defects known as congenital Zika syndrome (CZS). The mechanism by which ZIKV infection causes these adverse outcomes, and
Patrick S. Creisher, Jun Lei, Morgan L. Sherer, Amanda Dziedzic, Anne E. Jedlicka, Harish Narasimhan, Anna Chudnovets, Ariana D. Campbell, Anguo Liu, Andrew Pekosz, Irina Burd, Sabra L. Klein   +11 more
doaj   +1 more source

Estrogen Actions in Placental Vascular Morphogenesis and Spiral Artery Remodeling: A Comparative View between Humans and Mice

Cells, 2023
Estrogens, mainly 17β-estradiol (E2), play a critical role in reproductive organogenesis, ovulation, and fertility via estrogen receptors. E2 is also a well-known regulator of utero-placental vascular development and blood-flow dynamics throughout ...
Mariam Rusidzé, Adrien Gargaros, Chanaëlle Fébrissy, Charlotte Dubucs, Ariane Weyl, Jessie Ousselin, Jacqueline Aziza, Jean-François Arnal, Françoise Lenfant   +8 more
doaj   +1 more source

From Coxiella burnetii Infection to Pregnancy Complications: Key Role of the Immune Response of Placental Cells

Pathogens, 2021
The infection of pregnant animals and women by Coxiella burnetii, an intracellular bacterium, compromises both maternal health and foetal development. The placenta is targeted by C.
Sandra Madariaga Zarza, Soraya Mezouar, Jean-Louis Mege   +2 more
doaj   +1 more source