Results 11 to 20 of about 18,040 (249)
Bioengineering & Translational Medicine, 2023 The placenta is an essential organ that maintains the health of both the fetus and its mother. Understanding the development of human placenta has been hindered by the limitations of existing animal models and monolayer cell cultures.
Kangli Cui +5 more
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Clinical and Experimental Obstetrics & Gynecology, 2023 Background: The primary objective was to investigate how Forkhead Box A1 (FOXA1) contributes to late-onset preeclampsia (LOPE) and its impact on trophoblast invasion and migration.
Juan Zhu +8 more
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Cells, 2021 Preeclampsia (PE), a gestational hypertensive disease originating from the placenta, is characterized by an imbalance of various cellular processes.
Nina-Naomi Kreis +7 more
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Reproduction, 2012 Abstract This review summarises current knowledge about the specification, commitment and maintenance of the trophoblast lineage in mice and cattle. Results from gene expression studies, in vivo loss-of-function models and in vitro systems using trophoblast and embryonic stem cells have been assimilated into a model seeking to explain
Peter L, Pfeffer, David J, Pearton
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Frontiers in Virology, 2022 Zika virus (ZIKV) infection during pregnancy causes serious adverse outcomes to the developing fetus, including fetal loss and birth defects known as congenital Zika syndrome (CZS). The mechanism by which ZIKV infection causes these adverse outcomes, and
Patrick S. Creisher +11 more
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Cells, 2023 Estrogens, mainly 17β-estradiol (E2), play a critical role in reproductive organogenesis, ovulation, and fertility via estrogen receptors. E2 is also a well-known regulator of utero-placental vascular development and blood-flow dynamics throughout ...
Mariam Rusidzé +8 more
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Pathogens, 2021 The infection of pregnant animals and women by Coxiella burnetii, an intracellular bacterium, compromises both maternal health and foetal development. The placenta is targeted by C.
Sandra Madariaga Zarza +2 more
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Frontiers in Microbiology, 2022 Rubella virus (RuV) infections in pregnant women, especially first-trimester infections, can lead to congenital rubella syndrome (CRS). However, the mechanisms of fetal RuV infection are not completely understood, and it is not observed in every pregnant
Quang Duy Trinh +10 more
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Cells, 2023 The protein ezrin has been shown to enhance cancer cell motility and invasion leading to malignant behaviours in solid tumours, but a similar regulatory function in the early physiological reproduction state is, however, much less clear.
Maral E. A. Tabrizi +2 more
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Similarities and differences in placental development between humans and cynomolgus monkeys
Reproductive Medicine and Biology, 2023 Background The placenta is an extraembryonic organ, which is essential to maintain a normal pregnancy. However, placental development in humans is poorly understood because of technical and ethical reasons. Methods We analyzed the anatomical localization
Shoma Matsumoto +3 more
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