Results 91 to 100 of about 7,144 (202)
Tropoelastin Synthesis in Fetal Bovine Tissues
Collagen and Related Research, 1986 Tropoelastin was examined in bovine lung, aortic and ligament tissues using both organ culture and cell-free translation systems. The bovine tissues synthesized two tropoelastin polypeptides of approximately 70,000 and 68,000 daltons. Two polypeptides were also seen amongst the translation products directed by mRNAs isolated from each of the individual
J A, Foster, C B, Rich, S K, Horrigan
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Tunable, Temperature-Responsive Polynorbornenes with Side Chains Based on an Elastin Peptide Sequence [PDF]
, 2009 Random copolymers made by living ring-opening metathesis polymerization of norbornene monomers containing either the elastin peptide sequence -(VPGVG)- or pentaethylene glycol (see scheme; Mes=mesityl, pyr=pyridine) exhibit a lower critical solution ...
Conrad, Rosemary M., Grubbs, Robert H.
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The FEBS Journal, Volume 293, Issue 2, Page 418-442, January 2026.We analysed collagen XV expression in myocardial infarct samples and assessed how its deficiency affects cardiac responses, such as fibrogenesis and tissue stiffness. In mice, damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel ...
Sanna‐Maria Karppinen +15 more
wiley +1 more source
Matrix Biology Plus, 2019 Objective: Elastogenesis within the medial layer of the aortic wall involves a cascade of events orchestrated primarily by smooth muscle cells, including transcription of elastin and a cadre of elastin chaperone matricellular proteins, deposition and ...
Aneesh K. Ramaswamy +6 more
doaj +1 more source
Polymorphisms in the human tropoelastin gene modify in vitro self-assembly and mechanical properties of elastin-like polypeptides. [PDF]
PLoS ONE, 2012 Elastin is a major structural component of elastic fibres that provide properties of stretch and recoil to tissues such as arteries, lung and skin. Remarkably, after initial deposition of elastin there is normally no subsequent turnover of this protein ...
David He +7 more
doaj +1 more source
Elastin-based biopolymers for biomedical and biotechnological applications [PDF]
, 2014 Perhaps the most appealing opportunity is represented by gaining inspiration from nature for the precise tailoring of biomaterials with finely tuned unique functional properties.
Bandiera, Antonella
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Bioengineered vascular scaffolds: the state of the art [PDF]
, 2014 To date, there is increasing clinical need for vascular substitutes due to accidents, malformations, and ischemic diseases. Over the years, many approaches have been developed to solve this problem, starting from autologous native vessels to artificial ...
Bruno, A +4 more
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Silk–tropoelastin protein films for nerve guidance [PDF]
Acta Biomaterialia, 2015 Peripheral nerve regeneration may be enhanced through the use of biodegradable thin film biomaterials as highly tuned inner nerve conduit liners. Dorsal root ganglion neuron and Schwann cell responses were studied on protein films comprising silk fibroin blended with recombinant human tropoelastin protein.
James D, White +3 more
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Analytical Cellular Pathology, Volume 2026, Issue 1, 2026.Pulmonary fibrosis (PF) is a chronic and progressive interstitial lung disease characterized by excessive extracellular matrix (ECM) deposition and remodeling of lung structures. Currently, no effective clinical treatments exist to reverse or halt the progression of PF.
Zihan Zhou +5 more
wiley +1 more source
Frontiers in Bioengineering and BiotechnologyBackground: Osteoarthritis (OA) is a debilitating degenerative joint disease, leading to significant pain and disability. Despite advancements, current regenerative therapies, such as mesenchymal stem cells (MSCs), face challenges in clinical efficacy ...
Junjun Yang +11 more
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