Journal of Functional Biomaterials, 2023 Mesenchymal stem cells (MSCs) have recently been widely used to treat osteoarthritis (OA). Our prior research shows that tropoelastin (TE) increases MSC activity and protects knee cartilage from OA-related degradation.
Shuo Meng +8 more
doaj +1 more source
Transforming Growth Factor β1 and Tropoelastin Expression in Uterine Prolapse
Indonesian Journal of Obstetrics and Gynecology, 2016 Objective: To know the correlation of the expression of transforming growth factor beta (TGF-β1) and tropoelastin in uterine prolapse. Method: A cross-sectional study of 30 subjects suffered from uterine prolapse in the Department of Obstetrics and ...
Alvilusia Alvilusia +4 more
doaj +1 more source
Biomaterials for Corneal Regeneration. [PDF]
Adv Sci (Weinh)A variety of natural and synthetic biomaterials, along with decellularized cornea, have been employed in corneal wound healing. The current progress of biomaterials is summarized for corneal regeneration, and expect that these experiences and outcomes will inspire and provide practical strategies for the future development of corneal regeneration ...
Li Y, Wang Z.
europepmc +2 more sources
Cultured Human Keratinocytes Express Tropoelastin
Journal of Investigative Dermatology, 1997 We detected elastin mRNA in cultured normal human keratinocytes by RNase protection assay. The content of elastin mRNA was estimated at approximately one-twentieth of that of cultured skin fibroblasts. Tropoelastin polypeptide with a molecular weight of 68 kDa was detected in the preparation of culture medium of normal human keratinocytes by western ...
Hiroyoshi Kajiya +5 more
openalex +3 more sources
Journal of Functional Biomaterials, 2015 Bombyx mori silk fibroin membranes provide a potential delivery vehicle for both cells and extracellular matrix (ECM) components into diseased or injured tissues. We have previously demonstrated the feasibility of growing retinal pigment epithelial cells
Audra M. A. Shadforth +6 more
doaj +1 more source
The changes in chemical composition during development of the bovine nuchal ligament [PDF]
, 1967 Whole bovine nuchal ligaments, or portions thereof (in the case of commercially valuable animals), were obtained from 45 animals (28 fetal and 17 postnatal) ranging in age from 110 days of gestation to 10 yr. Insoluble elastin was quantitatively prepared
Cleary, E. G. +2 more
core +3 more sources
Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing [PDF]
, 2017 Tendon is composed of fascicles bound together by the interfascicular matrix (IFM). Energy storing tendons are more elastic and extensible than positional tendons; behaviour provided by specialisation of the IFM to enable repeated interfascicular sliding
A Heinz +48 more
core +3 more sources
Lipid Loading of Human Vascular Smooth Muscle Cells Induces Changes in Tropoelastin Protein Levels and Physical Structure [PDF]
, 2012 Aggregated low-density lipoprotein (agLDL), one of the main LDL modifications in the arterial intima, contributes to massive intracellular cholesteryl ester (CE) accumulation in human vascular smooth muscle cells (VSMC), which are major producers of ...
Augier +67 more
core +2 more sources
Temperature Dependent Conformational Transitions and Hydrogen Bond Dynamics of the Elastin-Like Octapeptide GVG(VPGVG): a Molecular Dynamics Study [PDF]
, 2004 A joint experimental / theoretical investigation of the elastin-like octapeptide GVG(VPGVG) was carried out. In this paper a comprehensive molecular dynamics study of the temperature dependent folding and unfolding of the octapeptide is presented.
Aalten +62 more
core +2 more sources
Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation [PDF]
, 2015 MFAP4 (microfibrillar-associated protein 4) is an extracellular glycoprotein found in elastic fibers without a clearly defined role in elastic fiber assembly.
Heumüller, Stefanie E +11 more
core +1 more source