Results 51 to 60 of about 7,724 (232)

Targeted Modulation of Tropoelastin Structure and Assembly

open access: hybridACS Biomaterials Science & Engineering, 2016
Tropoelastin, as the monomer unit of elastin, assembles into elastic fibers that impart strength and resilience to elastic tissues. Tropoelastin is also widely used to manufacture versatile materials with specific mechanical and biological properties.
Giselle C. Yeo   +3 more
openalex   +4 more sources

Plasma ion implantation enabled bio-functionalization of PEEK improves osteoblastic activity

open access: yesAPL Bioengineering, 2018
Slow appositional growth of bone in vivo is a major problem associated with polyether ether ketone (PEEK) based orthopaedic implants. Early stage promotion of osteoblast activity, particularly bone nodule formation, would help to improve contact between ...
Edgar A. Wakelin   +4 more
doaj   +1 more source

Influence of the architecture on the molecular mobility of synthetic fragments inspired from human tropoelastin [PDF]

open access: yes, 2015
This work deals with the vibrational, thermal and dielectric characterization of a synthetic peptide (S4) released during the proteolysis of human tropoelastin. This peptide was shown to form amyloid-like fibers implied in neurodegenerative pathologies.
Bochicchio, Brigida   +5 more
core   +2 more sources

A novel tropoelastin-based resorbable surgical mesh for pelvic organ prolapse repair

open access: yesMaterials Today Bio, 2020
Pelvic organ prolapse is a common condition that affects 1 in 4 women across all age groups. It is mainly caused by vaginal birth injury and can be exacerbated by obesity and increased age.
B. Aghaei-Ghareh-Bolagh   +8 more
doaj   +1 more source

Structural studies of elastic fibre and microfibrillar proteins

open access: yesMatrix Biology Plus, 2021
Elastic tissues owe their functional properties to the composition of their extracellular matrices, particularly the range of extracellular, multidomain extensible elastic fibre and microfibrillar proteins.
Mukti Singh   +3 more
doaj   +1 more source

Mir-29 repression in bladder outlet obstruction contributes to matrix remodeling and altered stiffness. [PDF]

open access: yesPLoS ONE, 2013
Recent work has uncovered a role of the microRNA (miRNA) miR-29 in remodeling of the extracellular matrix. Partial bladder outlet obstruction is a prevalent condition in older men with prostate enlargement that leads to matrix synthesis in the lower ...
Mari Ekman   +5 more
doaj   +1 more source

Tropoelastin improves adhesion and migration of intra-articular injected infrapatellar fat pad MSCs and reduces osteoarthritis progression

open access: yesBioactive Materials, 2022
Intra-articular injection of mesenchymal stem cells (MSCs) is a promising strategy for osteoarthritis (OA) treatment. However, more and more studies reveal that the injected MSCs have poor adhesion, migration, and survival in the joint cavity.
Junjun Yang   +15 more
doaj   +1 more source

Decreased lung fibroblast growth factor 18 and elastin in human congenital diaphragmatic hernia and animal models. [PDF]

open access: yes, 2007
International audienceRATIONALE: Lung hypoplasia in congenital diaphragmatic hernia (CDH) seems to involve impaired alveolar septation. We hypothesized that disturbed deposition of elastin and expression of fibroblast growth factor 18 (FGF18), an ...
Barlier-Mur, Anne-Marie   +6 more
core   +4 more sources

Cultured Human Keratinocytes Express Tropoelastin

open access: yesJournal of Investigative Dermatology, 1997
We detected elastin mRNA in cultured normal human keratinocytes by RNase protection assay. The content of elastin mRNA was estimated at approximately one-twentieth of that of cultured skin fibroblasts. Tropoelastin polypeptide with a molecular weight of 68 kDa was detected in the preparation of culture medium of normal human keratinocytes by western ...
Kajiya, Hiroyoshi   +5 more
openaire   +2 more sources

Tropoelastin: A versatile, bioactive assembly module [PDF]

open access: yesActa Biomaterialia, 2014
Elastin provides structural integrity, biological cues and persistent elasticity to a range of important tissues, including the vasculature and lungs. Its critical importance to normal physiology makes it a desirable component of biomaterials that seek to repair or replace these tissues.
Steven G, Wise   +6 more
openaire   +2 more sources

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