Results 61 to 70 of about 6,608 (237)
Journal of Aging Research, 2021 Skin aging is the result of superimposed intrinsic (individual) and extrinsic (e.g., UV exposure or nutrition) aging. Previous works have reported a relationship between UV irradiation and glycation in the aging process, leading, for example, to modified
Hervé Pageon +4 more
doaj +1 more source
Engineered elastin-like polypeptides: An efficient platform for enhanced cancer treatment
Frontiers in Pharmacology, 2023 Drug delivery systems (DDSs) have recently gained widespread attention for improving drug loading and delivery efficiency in treating many cancers. Elastin-like polypeptides (ELPs) are synthetic peptides derived from a precursor of elastin (tropoelastin),
Aiguo Jiang +4 more
doaj +1 more source
A comparative study of the elastic fibre system within the mouse and human cornea [PDF]
, 2018 The cornea relies on its organised extracellular matrix for maintaining transparency and biomechanical strength. Studies have identified an elastic fibre system within the human posterior cornea, thought to allow for slight deformations in response to ...
Feneck, Eleanor M. +3 more
core +2 more sources
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John +5 more
wiley +1 more source
Perivascular mast cells promote neointimal elastin deposition and suppress chronic vein graft restenosis in hyperlipidaemic mice. [PDF]
, 2017 Aims: Mast cells are versatile innate immune cells and are reported to promote vascular inflammation and neointimal lesion formation, thereby contributing to the development of vascular stenosis and atherosclerosis.
Kennedy, Simon +3 more
core +8 more sources
Alveolarization genes modulated by fetal tracheal occlusion in the rabbit model for congenital diaphragmatic hernia: a randomized study. [PDF]
PLoS ONE, 2013 BACKGROUND: The mechanisms by which tracheal occlusion (TO) improves alveolarization in congenital diaphragmatic hernia (CDH) are incompletely understood.
Aline Vuckovic +4 more
doaj +1 more source
Roles of fibronectin isoforms in neonatal vascular development and matrix integrity [PDF]
, 2018 Fibronectin (FN) exists in two forms—plasma FN (pFN) and cellular FN (cFN). Although the role of FN in embryonic blood vessel development is well established, its function and the contribution of individual isoforms in early postnatal vascular ...
Brinckmann, Jurgen +6 more
core +2 more sources
Tailoring the biofunctionality of collagen biomaterials via tropoelastin incorporation and EDC-crosslinking [PDF]
, 2021 Recreating the cell niche of virtually all tissues requires composite materials fabricated from multiple extracellular matrix (ECM) macromolecules.
Bax, Daniel V +5 more
core +2 more sources
Targeted Modulation of Tropoelastin Structure and Assembly
ACS Biomaterials Science & Engineering, 2016 Tropoelastin, as the monomer unit of elastin, assembles into elastic fibers that impart strength and resilience to elastic tissues. Tropoelastin is also widely used to manufacture versatile materials with specific mechanical and biological properties.
Yeo, Giselle C. +3 more
openaire +4 more sources
Multifunctional SilkTropoelastin Biomaterial Systems [PDF]
Israel Journal of Chemistry, 2013 AbstractNew multifunctional, degradable, polymeric biomaterial systems would provide versatile platforms to address cell and tissue needs in both in vitro and in vivo environments. While protein‐based composites or alloys are the building blocks of biological organisms, similar systems have not been largely exploited, to date, to generate ad hoc ...
David L. Kaplan +3 more
openaire +3 more sources