Results 61 to 70 of about 7,724 (232)

Searching low-energy conformations of two elastin sequences

open access: yes, 2004
The three-dimensional structures of two common repeat motifs Val$^1$-Pro$^2$-Gly$^3$-Val$^4$-Gly$^5$ and Val$^1$-Gly$^2$-Val$^3$-Pro$^4$-Gly$^5$-Val$^6$-Gly$^7$-Val$^8$-Pro$^9$ of tropoelastin are investigated by using the multicanonical simulation ...
Arkin, H.
core   +1 more source

Lysyl Oxidase Enhances the Deposition of Tropoelastin through the Catalysis of Tropoelastin Molecules on the Cell Surface

open access: diamondBiological & Pharmaceutical Bulletin, 2017
The cross-linking of elastin by lysyl oxidase (LOX) family members is essential for the integrity and elasticity of elastic fibers, which play an important role in the characteristic resilience of various tissues. However, the temporal sequence of oxidation by LOX during elastic fiber formation is still incompletely understood.
Fumiaki Sato   +5 more
openalex   +4 more sources

Elastin haploinsufficiency induces alternative aging processes in the aorta [PDF]

open access: yes, 2008
Elastin, the main component of elastic fibers, is synthesized only in early life and provides the blood vessels with their elastic properties. With aging, elastin is progressively degraded, leading to arterial enlargement, stiffening, and dysfunction ...
Boyle, Walter A   +13 more
core   +3 more sources

Extracellular Matrix Molecules Facilitating Vascular Biointegration

open access: yesJournal of Functional Biomaterials, 2012
All vascular implants, including stents, heart valves and graft materials exhibit suboptimal biocompatibility that significantly reduces their clinical efficacy.
Martin K.C. Ng   +3 more
doaj   +1 more source

Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]

open access: yes, 2017
Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J   +5 more
core   +3 more sources

Leptospira Immunoglobulin-Like Protein B Interacts with the 20th Exon of Human Tropoelastin Contributing to Leptospiral Adhesion to Human Lung Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Leptospira immunoglobulin-like protein B (LigB), a surface adhesin, is capable of mediating the attachment of pathogenic leptospira to the host through interaction with various components of the extracellular matrix (ECM).
Ching-Lin Hsieh   +6 more
doaj   +1 more source

Biocatalytic Synthesis of Polymers of Precisely Defined Structures [PDF]

open access: yes, 1999
The fabrication of functional nanoscale devices requires the construction of complex architectures at length scales characteristic of atoms and molecules. Currently microlithography and micro-machining of macroscopic objects are the preferred methods for
AB Mauger   +59 more
core   +1 more source

Elastin-like Polypeptides in Development of Nanomaterials for Application in the Medical Field

open access: yesFrontiers in Nanotechnology, 2022
Elastin-like polypeptides (ELPs) are biopolymers formed by amino acid sequences derived from tropoelastin. These biomolecules can be soluble below critical temperatures, forming aggregates at higher temperatures, which makes them an interesting source ...
Letícia Ferreira Lima   +19 more
doaj   +1 more source

Trends in the design and use of elastin-like recombinamers as biomaterials [PDF]

open access: yes, 2019
Producción CientíficaElastin-like recombinamers (ELRs), which derive from one of the repetitive domains found in natural elastin, have been intensively studied in the last few years from several points of view.
Acosta Rodríguez, Sergio   +3 more
core   +2 more sources

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

open access: yesAdvanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee   +9 more
wiley   +1 more source

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