Results 61 to 70 of about 7,144 (202)

Extracellular Matrix Molecules Facilitating Vascular Biointegration [PDF]

, 2014
All vascular implants, including stents, heart valves and graft materials exhibit suboptimal biocompatibility that significantly reduces their clinical efficacy.
Michael, Praveesuda, Ng, Martin K.C., Waterhouse, Anna, Wise, Steven G.   +3 more
core   +1 more source

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

Advanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh, Azin Khodaei, Pardis Keikhosravani, Masoud Zhianmanesh, Yiyun Xia, Aaron Gilmour, Sina Naficy, Andrea Guzina, Daniella Bianchi, Khoon S. Lim, Fariba Dehghani, Saber Amin Yavari, Marcela Bilek, Giselle C. Yeo, Behnam Akhavan   +14 more
wiley   +1 more source

Characterization of Endothelial Progenitor Cell Interactions with Human Tropoelastin. [PDF]

PLoS ONE, 2015
The deployment of endovascular implants such as stents in the treatment of cardiovascular disease damages the vascular endothelium, increasing the risk of thrombosis and promoting neointimal hyperplasia.
Young Yu, Steven G Wise, Praveesuda L Michael, Daniel V Bax, Gloria S C Yuen, Matti A Hiob, Giselle C Yeo, Elysse C Filipe, Louise L Dunn, Kim H Chan, Hamid Hajian, David S Celermajer, Anthony S Weiss, Martin K C Ng   +13 more
doaj   +1 more source

Engineered elastin-like polypeptides: An efficient platform for enhanced cancer treatment

Frontiers in Pharmacology, 2023
Drug delivery systems (DDSs) have recently gained widespread attention for improving drug loading and delivery efficiency in treating many cancers. Elastin-like polypeptides (ELPs) are synthetic peptides derived from a precursor of elastin (tropoelastin),
Aiguo Jiang, Xinqiang Guan, Lianping He, Xingang Guan, Xingang Guan   +4 more
doaj   +1 more source

Heparan sulfate affects elastin deposition in fibroblasts cultured from donors of different ages [PDF]

, 2012
Heparan sulfate (HS), due to its presence on the cell surface and in the extracellular milieu and its ability to modulate cell signaling, has a fundamental role in both physiological and pathological conditions.
ANNOVI, Giulia, BORALDI, Federica, GUERRA, Deanna, Moscarelli, P., Parma, B., QUAGLINO, Daniela, Sommer, P., TIOZZO, Roberta   +7 more
core   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Elastogenic protein expression of a highly elastic murine spinal ligament: the ligamentum flavum.

PLoS ONE, 2012
Spinal ligaments, such as the ligamentum flavum (LF), are prone to degeneration and iatrogenic injury that can lead to back pain and nerve dysfunction. Repair and regeneration strategies for these tissues are lacking, perhaps due to limited understanding
Jeffrey P Brown, Rachel M Lind, Anthony F Burzesi, Catherine K Kuo   +3 more
doaj   +1 more source

UVA Exposure Combined with Glycation of the Dermis Are Two Catalysts for Skin Aging and Promotes a Favorable Environment to the Appearance of Elastosis

Journal of Aging Research, 2021
Skin aging is the result of superimposed intrinsic (individual) and extrinsic (e.g., UV exposure or nutrition) aging. Previous works have reported a relationship between UV irradiation and glycation in the aging process, leading, for example, to modified
Hervé Pageon, Hélène Zucchi, Sylvie Ricois, Philippe Bastien, Daniel Asselineau   +4 more
doaj   +1 more source

A comparative study of the elastic fibre system within the mouse and human cornea [PDF]

, 2018
The cornea relies on its organised extracellular matrix for maintaining transparency and biomechanical strength. Studies have identified an elastic fibre system within the human posterior cornea, thought to allow for slight deformations in response to ...
Feneck, Eleanor M., Lewis, Philip N., Meek, Keith M., Ralphs, Jim   +3 more
core   +2 more sources

Biomaterials derived from silk–tropoelastin protein systems [PDF]

Biomaterials, 2010
A structural protein blend system based on silkworm silk fibroin and recombinant human tropoelastin is described. Silk fibroin, a semicrystalline fibrous protein with beta-sheet crystals provides mechanical strength and controllable biodegradation, while tropoelastin, a noncrystallizable elastic protein provides elasticity.
Xiao, Hu, Xiuli, Wang, Jelena, Rnjak, Anthony S, Weiss, David L, Kaplan   +4 more
openaire   +2 more sources