Influence of cellular mechano-calcium feedback in numerical models of cardiac electromechanics [PDF]
arXivMultiphysics and multiscale mathematical models enable the non-invasive study of cardiac function. These models often rely on simplifying assumptions that neglect certain biophysical processes to balance fidelity and computational cost. In this work, we propose an eikonal-based framework that incorporates mechano-calcium feedback -- the effect of ...
arxiv
Immune Checkpoint Inhibitors and Cardiovascular Adverse Events
ESC Heart Failure, EarlyView.Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna +4 more
wiley +1 more source
Progress in COVID research and developments during pandemic
VIEW, Volume 3, Issue 6, December 2022., 2022 The pandemic respiratory disease COVID‐19 has spread over the globe within a small span of time. Generally, there are two important points are being highlighted and considered towards the successful diagnosis and treatment process. The first point includes the reduction of the rate of infections and the next one is the decrease of the death rate.
Sudheesh K. Shukla +5 more
wiley +1 more source
Impact on clinical guideline adherence of Orient-COVID, a CDSS based on dynamic medical decision trees for COVID19 management: a randomized simulation trial [PDF]
arXivBackground: The adherence of clinicians to clinical practice guidelines is known to be low, including for the management of COVID-19, due to their difficult use at the point of care and their complexity. Clinical decision support systems have been proposed to implement guidelines and improve adherence.
arxiv
Characterization of pig skeletal muscle transcriptomes in response to low temperature
Veterinary Medicine and Science, Volume 9, Issue 1, Page 181-190, January 2023., 2023 Low temperature changes the gene expression pattern and biological pathway in pig skeletal muscle. Under low temperature, biological pathways of lipid, amino acid, and carbohydrate metabolism; signal transduction; endocrine, immune, and nervous system; cardiovascular disease; infectious diseases caused by bacteria or viruses; and neurodegenerative ...
DongJie Zhang +4 more
wiley +1 more source
The sites of phosphorylation of rabbit cardiac troponin I by adenosine 3′:5′-cyclic monophosphate-dependent protein kinase. Effect of interaction with troponin C [PDF]
, 1977 Arthur J.G. Moir, S V Perry
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Clinical characteristics and long‐term outcomes in patients with apical hypertrophic cardiomyopathy
ESC Heart Failure, EarlyView.Abstract Aims As a special type of hypertrophic cardiomyopathy (HCM), apical HCM (ApHCM) has different clinical characteristics while its nature history and prognosis are not well recognized. We aimed to describe the characteristics and outcomes of ApHCM and identify predictors of adverse outcomes.
Meng Guo +3 more
wiley +1 more source
Annals of the American Thoracic Society, 2019 Scott K. Aberegg, David A. Kaufman
openaire +2 more sources
Reconstitution of Troponin Activity from Three Protein Components
, 1971 Marion L. Greaser, J. Gergely
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ESC Heart Failure, EarlyView.Systematic approach to dilated cardiomyopathy diagnosis. Dilated cardiomyopathy is a clinical diagnosis characterized by the presence of left ventricular dilatation and systolic disfunction unexplained by abnormal loading conditions or coronary artery disease.
Kristian Galanti +14 more
wiley +1 more source