Results 191 to 200 of about 206,412 (354)

Association of ventricular–arterial coupling with biomarkers involved in heart failure pathophysiology – the STANISLAS cohort

open access: yesEuropean Journal of Heart Failure, EarlyView.
Association of ventricular–arterial coupling with heart failure (HF) biomarkers in the STANISLAS cohort. MMP, matrix metalloproteinase; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide. Aims Impaired left ventricular–arterial coupling (VAC) has been shown to correlate with worse prognosis in cardiac diseases and heart failure (HF).
Hannes Holm   +12 more
wiley   +1 more source

Large‐scale genetic screens identify BET‐1 as a cytoskeleton regulator promoting actin function and life span

open access: yesAging Cell, Volume 22, Issue 1, January 2023., 2023
Using a cross‐species screening approach combining genome‐wide CRISPR‐Cas9 screening in human fibroblasts (1) and synthetic lethality screening in Caenorhabditis elegans (2), we identified BET‐1/BRD4 as a novel regulator of the actin cytoskeleton (3). BET‐1/BRD4 promotes actin filament stability in C.
Gilberto Garcia   +16 more
wiley   +1 more source

Cardiac damage biomarkers and heart rate variability following a 118-km mountain race: relationship with performance and recovery [PDF]

open access: yes, 2019
This study aimed to assess the release of cardiac damage biomarkers jointly with cardiac autonomic modulation after a mountain ultramarathon. Such knowledge and the possible relationship of these markers with race time is of primary interest to establish
Collado-Boira, Eladio   +4 more
core   +1 more source

The Mayo ATTR‐CM score versus other diagnostic scores and cardiac biomarkers in patients with suspected cardiac amyloidosis

open access: yesEuropean Journal of Heart Failure, EarlyView.
Proposed algorithm to screen for transthyretin cardiac amyloidosis (ATTR‐CA). AL‐CA, immunoglobulin light‐chain cardiac amyloidosis; AMYLI, AMYLoidosis Index; AUC, area under the curve; IWT, increased wall thickness; LVEF, left ventricular ejection fraction; PYP, pyrophosphate.
Giovanni Battista Bonfioli   +11 more
wiley   +1 more source

Microvascular obstruction in cardiac amyloidosis

open access: yesEuropean Journal of Heart Failure, EarlyView.
Abstract Aims Cardiac amyloidosis (CA) is characterized by deposition of amyloid fibrils within the extracellular space, causing disarray of the myocardial structure and capillary architecture. This study aims to characterize the prevalence of microvascular obstruction (MVO) in patients with CA and to assess the association between MVO and prognosis ...
Lucrezia Netti   +19 more
wiley   +1 more source

New cardiovascular biomarkers in patients with advanced cancer – A prospective study comparing MR‐proADM, MR‐proANP, copeptin, high‐sensitivity troponin T and NT‐proBNP

open access: yesEuropean Journal of Heart Failure, EarlyView.
(A) Univariable receiver operating characteristic (ROC) curves for all biomarkers. (B) Kaplan–Meier curves for best cut‐point of mid‐regional pro‐adrenomedullin (MR‐proADM) for survival (n = 442). AUC, area under the curve; CI, confidence interval; HR, hazard ratio; hsTnT, high‐sensitivity troponin T; MR‐proANP, mid‐regional pro‐atrial natriuretic ...
Markus S. Anker   +18 more
wiley   +1 more source

Syncope with QT‐interval prolongation and T‐wave inversion in anterior and inferior leads: Foreboder of a life‐threatening condition?

open access: yesAnnals of Noninvasive Electrocardiology, Volume 28, Issue 1, January 2023., 2023
The patient’s ECG exhibited QT‐interval prolongation with T‐wave inversion in anterior and inferior leads that, together with CT‐pulmonary angiography findings, strongly suggested PE. This ECG pattern is crucial for diagnosing PE. Abstract Even though patients with pulmonary embolism usually present with respiratory distress and tachycardia, the ...
Jing‐Xiu Li   +3 more
wiley   +1 more source

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