Troponin T3 regulates nuclear localization of the calcium channel Cavβ1a subunit in skeletal muscle [PDF]
The voltage-gated calcium channel (Cav) β1a subunit (Cavβ1a) plays an important role in excitation-contraction coupling (ECC), a process in the myoplasm that leads to muscle-force generation. Recently, we discovered that the Cavβ1a subunit travels to the
Delbono, Osvaldo +7 more
core +2 more sources
Influence of case definition on incidence and outcome of acute coronary syndromes [PDF]
© 2016, BMJ Publishing Group. All rights reserved. Objective: Acute coronary syndromes (ACS) are common, but their incidence and outcome might depend greatly on how data are collected.
Alamgir, Farqad +11 more
core +2 more sources
Introduction: Homocysteine (HCY), troponin, cardiac markers, folic acid and Vitamin B12 are known as the potential biomarkers for acute myocardial infarction (AMI) diagnosis.
Abbas Ali Niazi +5 more
doaj +1 more source
Dynamics and calcium association to the N-terminal regulatory domain of human cardiac troponin C: a multiscale computational study. [PDF]
Troponin C (TnC) is an important regulatory molecule in cardiomyocytes. Calcium binding to site II in TnC initiates a series of molecular events that result in muscle contraction.
Huber, Gary +4 more
core +2 more sources
Background Use of snus, a smokeless tobacco product, is increasing in Scandinavia. Strenuous physical activity is associated with an acute increase in high‐sensitivity cardiac troponin (swhs‐cTn) concentrations.
Julia Brox Skranes +6 more
doaj +1 more source
Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis. [PDF]
BACKGROUND: Elevated serum cardiac troponin T (cTnT) and I (cTnI) can occur in patients with chronic kidney disease. Differences in cTn concentrations between cTnT and cTnI have been reported but the mechanism of such discrepancy has not been ...
Adams +32 more
core +1 more source
Financial impact of a targeted reduction in cardiac enzyme testing at a community hospital [PDF]
Objectives: Nearly one-third of healthcare costs are potentially avoidable and would not compromise medical care if eliminated. Therefore, we sought to evaluate the financial impact of reduction in use of creatinine kinase (CK)-MB and myoglobin tests ...
Li Zhang +5 more
doaj +1 more source
Prognostic Value of Elevated Cardiac Troponin I After Aneurysmal Subarachnoid Hemorrhage
Object: Patients with aneurysmal subarachnoid hemorrhage (aSAH) have an increased incidence of cardiac events and short-term unfavorable neurological outcomes during the acute phase of bleeding.
Fa Lin +36 more
doaj +1 more source
High-sensitivity cardiac troponin T and copeptin assays to improve diagnostic accuracy of exercise stress test in patients with suspected coronary artery disease [PDF]
Background: The average diagnostic sensitivity of exercise stress tests (ESTs) is lower than that of other non-invasive cardiac stress tests. The aim of the study was to examine whether high-sensitivity cardiac troponin T (hs-cTnT) or copeptin ...
Dörr, Oliver +9 more
core +1 more source
Evidence and Cost Effectiveness Requirements for Recommending New Biomarkers. [PDF]
B-type natriuretic peptide (BNP) and NT-proBNP are widely used plasma biomarkers for the diagnosis of acute decompensated heart failure and prognosis for future cardiac disease.
Collinson, P
core +4 more sources

