Results 41 to 50 of about 159,062 (216)

Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis.

, 2014
BACKGROUND: Elevated serum cardiac troponin T (cTnT) and I (cTnI) can occur in patients with chronic kidney disease. Differences in cTn concentrations between cTnT and cTnI have been reported but the mechanism of such discrepancy has not been ...
Collinson, PO, Gaze, D.C., David C Gaze, Collinson, P., Gaze, DC, Paul O Collinson   +5 more
core   +1 more source

Release and Clearance Mechanisms of Cardiac Troponin [PDF]

, 2020
Myocardial infarction (MI) is often suspected when a patient presents with chest pain. MI is defined as cardiac necrosis due to ischemia, most often mediated through impaired coronary perfusion.
Karin, Starnberg
core   +1 more source

Relationship Between Peak Troponin Values and Long‐Term Ischemic Events Among Medically Managed Patients With Acute Coronary Syndromes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThe relationship between troponin level and outcomes among patients with non‐ST‐segment elevation ACS is established, but the relationship of troponin level with long‐term outcomes among medically managed non‐ST‐segment elevation ACS patients ...
Sarah A. Goldstein, L. Kristin Newby, Derek D. Cyr, Megan Neely, Thomas F. Lüscher, Eileen B. Brown, Harvey D. White, E. Magnus Ohman, Matthew T. Roe, Christian W. Hamm   +9 more
doaj   +1 more source

Financial impact of a targeted reduction in cardiac enzyme testing at a community hospital [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2016
Objectives: Nearly one-third of healthcare costs are potentially avoidable and would not compromise medical care if eliminated. Therefore, we sought to evaluate the financial impact of reduction in use of creatinine kinase (CK)-MB and myoglobin tests ...
Li Zhang, Anne M. Sill, Ilene Young, Sabreen Ahmed, Maria Morales, Sapna Kuehl   +5 more
doaj   +1 more source

Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundAnthracyclines are associated with cardiotoxic effects. Cardiovascular biomarkers may reflect myocardial injury, dysfunction, inflammation, and fibrosis and may precede and predict the development of left ventricular impairment. The aim of this
Geeta Gulati, Siri L. Heck, Helge Røsjø, Anne H. Ree, Pavel Hoffmann, Tor‐Arne Hagve, Jon Norseth, Berit Gravdehaug, Kjetil Steine, Jürgen Geisler, Torbjørn Omland   +10 more
doaj   +1 more source

Diagnostic Thresholds for Pre–Diabetes Mellitus and Diabetes Mellitus and Subclinical Cardiac Disease in the General Population: Data From the ACE 1950 Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Diabetes mellitus (DM) is associated with left ventricular remodeling and incident heart failure, but the association between glycated hemoglobin A1c (HbA1c) and subclinical cardiac disease is not established.
Peder L. Myhre, Magnus N. Lyngbakken, Trygve Berge, Ragnhild Røysland, Erika N. Aagaard, Osman Pervez, Brede Kvisvik, Jon Brynildsen, Jon Norseth, Arnljot Tveit, Kjetil Steine, Torbjørn Omland, Helge Røsjø   +12 more
doaj   +1 more source

Pulmonary embolism initially misdiagnosed as perimyocarditis in a young patıent

Annals of Cardiac Anaesthesia, 2022
Pulmonary embolism is a common cardiovascular emergency. In case of delayed diagnosis and treatment morbidity and mortality is high. In this report, we presented a case of pulmonary embolism without apparent risk factors, which was initially misdiagnosed
Oguz Kilic, Alperen E Akgun, Furkan Ufuk, Ipek Buber, Ismail D Kilic   +4 more
doaj   +1 more source

Diagnostics and management of patients with type 2 myocardial infarction

Consilium Medicum, 2021
Myocardial infarction (MI) is an acute myocardial injury (confirmed by increasing|decreasing of cardiac troponin T and/or I) in conditions of proven acute myocardial ischemia, manifested by clinical symptoms of acute ischemia and/or ischemic changes on ...
Elena V. Reznik, Yuri Yu. Golubev, Liudmila M. Mikhaleva   +2 more
doaj   +1 more source

Modulation of structure and dynamics of cardiac troponin by phosphorylation and mutations revealed by molecular dynamics simulations

, 2022
Phosphorylation of cardiac muscle troponin I by protein kinase A enhances troponin regulatory dynamics and is an essential part of the’ flight or fight’ response to adrenaline.
ian, gould, Zeyu, Yang, Steve, Marston
core   +1 more source

Immune Checkpoint Inhibitor-Related Adverse Cardiovascular Events in Patients With Lung Cancer

JACC. CardioOncology, 2019
Objectives: The purpose of this study was to evaluate whether immune checkpoint inhibitors (ICIs) are associated with an increased risk of major adverse cardiovascular events (MACE) compared with non-ICI therapies in patients with lung cancer. Background:
Kalyan R. Chitturi, DO, Jiaqiong Xu, PhD, Raquel Araujo-Gutierrez, MD, Arvind Bhimaraj, MD, Ashrith Guha, MD, Imad Hussain, MD, Mahwash Kassi, MD, Eric H. Bernicker, MD, Barry H. Trachtenberg, MD   +8 more
doaj   +1 more source