Results 61 to 70 of about 276,777 (390)

High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study.

open access: yesCirculation, 2019
BACKGROUND We assessed whether plasma troponin I measured by a high-sensitivity assay (hs-TnI) is associated with incident cardiovascular disease (CVD) and mortality in a community-based sample without prior CVD.
Xiaoming Jia   +13 more
semanticscholar   +1 more source

The 99th percentile of reference population for cTnI and cTnT assay: Methodology, pathophysiology and clinical implications [PDF]

open access: yes, 2017
According to recent international guidelines, including the 2012 Third Universal Definiton of Myocardial Infarction by the Joint ESC/ACCF/AHA/WHF Task Force, an increase in cardiac troponin (cTn) levels over the 99th percentile upper reference limit ...
Clerico, Aldo   +6 more
core   +1 more source

Diagnosing myocardial injury in the high-sensitivity troponin era

open access: yesEmergency Care Journal, 2018
Not available.
Giuseppe Lippi, Gianfranco Cervellin
doaj   +1 more source

Troponins in equipoise [PDF]

open access: yesEuropean Heart Journal, 2016
This editorial refers to ‘Impact of high-sensitivity cardiac troponin on use of coronary angiography, cardiac stress testing, and time to discharge in suspected acute myocardial infarction’, by R. Twerenbold et al. doi:10.1093/eurheartj/ehw232. Equipose ( noun | equi·poise | \e-kwə-p⊙iz, ē-\): a state of equilibrium1Well-executed clinical trials have ...
openaire   +3 more sources

High-Sensitivity Cardiac Troponin and the Universal Definition of Myocardial Infarction

open access: yesCirculation, 2019
Supplemental Digital Content is available in the text. Background: The introduction of more sensitive cardiac troponin assays has led to increased recognition of myocardial injury in acute illnesses other than acute coronary syndrome.
A. Chapman   +21 more
semanticscholar   +1 more source

Cardiac Troponin Assays: Guide to Understanding Analytical Characteristics and Their Impact on Clinical Care.

open access: yesClinical Chemistry, 2017
BACKGROUND Cardiac troponin I (cTnI) and cardiac troponin T (cTnT) determinations are fixtures in clinical practice and research. Cardiac troponin testing has been the standard of practice for the diagnosis of acute myocardial infarction (AMI), early ...
F. Apple   +3 more
semanticscholar   +1 more source

The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy [PDF]

open access: yes, 2008
Background: Hypertrophic (HCM) and dilated (DCM) cardiomyopathies results from sarcomeric protein mutations, including cardiac troponin T (cTnT, TNNT2).
Ahmad, F   +17 more
core   +4 more sources

Myocardial Injury in the Era of High-Sensitivity Cardiac Troponin Assays: A Practical Approach for Clinicians.

open access: yesJAMA cardiology, 2019
Importance Traditionally, elevated troponin concentrations were synonymous with myocardial infarction. But with improvements in troponin assays, elevated concentrations without overt myocardial ischemia are now more common; this is referred to as ...
Cian P. McCarthy   +6 more
semanticscholar   +1 more source

Development of Optical Biosensor Technologies for Cardiac Troponin Recognition [PDF]

open access: yes, 2015
Acute myocardial infarction (AMI) is the leading cause of death among cardiovascular diseases. Among the numerous attempts to develop coronary marker concepts into clinical strategies, cardiac troponin is known as a specific marker for coronary events ...
Abdolrahim, Mojgan   +5 more
core   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

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