Results 121 to 130 of about 162,145 (312)

The effect of Mg²⁺ on Ca²⁺ binding to cardiac troponin C in hypertrophic cardiomyopathy associated TNNC1 variants. [PDF]

FEBS J, 2022
Rayani K, Hantz ER, Haji-Ghassemi O, Li AY, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF.   +8 more
europepmc   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

Binding of calcium and magnesium to human cardiac troponin C. [PDF]

J Biol Chem, 2021
Rayani K, Seffernick J, Li AY, Davis JP, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF.   +8 more
europepmc   +1 more source

Prognostic role of high‐sensitivity cardiac troponin T in patients with cardiac sarcoidosis: insights from ILLUMINATE‐CS

ESC Heart Failure, Volume 12, Issue 2, Page 869-878, April 2025.
Abstract Aims The prognostic role of high‐sensitivity cardiac troponin T (hs‐cTnT) as a biomarker in patients with cardiac sarcoidosis (CS) has yet to be fully determined, especially when compared with B‐type natriuretic peptide (BNP). Methods and Results In this post‐hoc analysis of the ILLUMINATE‐CS (ILLUstration of the Management and prognosIs of ...
Yuichi Baba, Toru Kubo, Takeru Nabeta, Yuya Matsue, Takeshi Kitai, Yoshihisa Naruse, Tatsunori Taniguchi, Hidekazu Tanaka, Takahiro Okumura, Kenji Yoshioka, Hiroaki Kitaoka   +10 more
wiley   +1 more source

X-ray structure of a human cardiac muscle troponin C/troponin I chimera in two crystal forms. [PDF]

Acta Crystallogr F Struct Biol Commun, 2022
Yan C, Sack JS.
europepmc   +1 more source

Evaluation of the utility of cardiac biomarkers for risk stratification in patients with lower extremity artery disease: A retrospective study.

PLoS ONE
Critical limb threatening ischemia (CLTI) is associated with a one-year mortality rate of up to 25% making prompt diagnosis essentially. This study aims to investigate if cardiac biomarkers may serve as an effective tool for risk stratification in ...
Leyla Schweiger, Reinhard B Raggam, Gabor Toth-Gayor, Philipp Jud, Alexander Avian, Viktoria Nemecz, Katharina Gütl, Marianne Brodmann, Thomas Gary   +8 more
doaj   +1 more source

Computational Methods Elucidate Consequences of Mutations and Post-translational Modifications on Troponin I Effective Concentration to Troponin C. [PDF]

J Phys Chem B, 2021
Cool AM, Lindert S.
europepmc   +1 more source

Cardiomyocyte Nuclear Pleomorphism in a Mouse Model of Inherited Hypertrophic Cardiomyopathy

Journal of Cardiovascular Development and Disease
Mutations in genes encoding sarcomeric proteins are a common cause of cardiomyopathy and sudden cardiac death in humans. We evaluated the hypothesis that myofilament dysfunction is coupled to morphological and functional alterations of cardiomyocyte ...
Jamie R. Johnston, Isabella Leite Coscarella, Carson L. Rose, Yun Shi, Hosna Rastegarpouyani, Karissa M. Dieseldorff Jones, Jennifer M. Le Patourel, Feyikemi Ogunfuwa, Adriano S. Martins, Kathryn M. Crotty, Katherine M. Ward Molla, Tyler R. Reinoso, Taylor L. Waldmann, Jerome Irianto, Yue Julia Wang, Lili Wang, Björn C. Knollmann, Jose R. Pinto, Prescott Bryant Chase   +18 more
doaj   +1 more source

The effect of variable troponin C mutation thin filament incorporation on cardiac muscle twitch contractions. [PDF]

J Mol Cell Cardiol, 2021
Mijailovich SM, Prodanovic M, Poggesi C, Powers JD, Davis J, Geeves MA, Regnier M.   +6 more
europepmc   +1 more source

Dynamic Light Scattering from Semidilute Actin Solutions: A Study of Hydrodynamic Screening, Filament Bending Stiffness and the Effect of Tropomyosin/Troponin-Binding

, 1995
Quasi-elastic light scattering (QELS) is applied to investigate the effect of the tropomyosin/troponin complex (Tm/Tn) on the stiffness of actin filaments. The importance of hydrodynamic screening in semidilute solutions is demonstrated.
Baermann, M., Frey, E., Goetter, R., Kroy, K., Sackmann, E.   +4 more
core   +1 more source