The regulation of troponins I, C and ANP by GATA4 and Nkx2-5 in heart of hibernating thirteen-lined ground squirrels, Ictidomys tridecemlineatus. [PDF]
Hibernation is an adaptive strategy used by various mammals to survive the winter under situations of low ambient temperatures and limited or no food availability.
Bryan E Luu +3 more
doaj +1 more source
Tissue-specific interactions of TNI isoforms with other TN subunits and tropomyosins in C. elegans: The role of the C- and N-terminal extensions [PDF]
The aim of this study is to investigate the function of the C-terminal extension of three troponin I isoforms, that are unique to the body wall muscles of Caenorhabditis elegans and to understand the molecular interactions within the TN complex between ...
al-Hillawi +35 more
core +1 more source
Measurement of Calcium Dissociation Rates from Troponin C in Rigor Skeletal Myofibrils
Ca2+ dissociation from the regulatory domain of troponin C may influence the rate of striated muscle relaxation. However, Ca2+ dissociation from troponin C has not been measured within the geometric and stoichiometric constraints of the muscle fiber ...
Sean C Little +4 more
doaj +1 more source
Effects of temperature and method of heat treatment on myofibrillar proteins of pork [PDF]
During the tests in this paper, meat processing was carried out at different temperatures between the range of 51°C to 100°C. The meat was processed by dry heat (roasting) and wet heat treatments (cooking) in water at atmospheric pressure. After
Vujadinović Dragan +3 more
doaj +1 more source
Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core +2 more sources
The Effect of High-Dose Vitamin C on Biochemical Markers of Myocardial Injury in Coronary Artery Bypass Surgery [PDF]
Objective: To evaluate the effect of high-dose vitamin C on cardiac reperfusion injury and plasma levels of creatine kinase-muscle/brain (CK-MB), troponin I, and lactate dehydrogenase (LDH) in patients undergoing coronary artery bypass grafting (CABG ...
Nafiseh Emadi +3 more
doaj +1 more source
Drug Binding to Cardiac Troponin C [PDF]
Compounds that sensitize cardiac muscle to Ca(2+) by intervening at the level of regulatory thin filament proteins would have potential therapeutic benefit in the treatment of myocardial infarctions. Two putative Ca(2+) sensitizers, EMD 57033 and levosimendan, are reported to bind to cardiac troponin C (cTnC).
Q, Kleerekoper, J A, Putkey
openaire +2 more sources
Elevated serum levels of cardiac troponin and C-reactive protein are associated with all-cause and cardiovascular mortality in patients with end-stage renal disease.
Wei-Jie Li +6 more
doaj +1 more source
Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. [PDF]
The contractile response of the heart can be altered by disease-related protein modifications to numerous contractile proteins. By utilizing an IAANS labeled fluorescent troponin C, [Formula: see text], we examined the effects of ten disease-related ...
Bin Liu +4 more
doaj +1 more source
Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen +5 more
core +1 more source

