Measurement of Calcium Dissociation Rates from Troponin C in Rigor Skeletal Myofibrils [PDF]
Ca2+ dissociation from the regulatory domain of troponin C may influence the rate of striated muscle relaxation. However, Ca2+ dissociation from troponin C has not been measured within the geometric and stoichiometric constraints of the muscle fiber ...
Sean C Little +4 more
doaj +2 more sources
Interaction of bepridil with the cardiac troponin C/troponin I complex [PDF]
We have investigated the binding of bepridil to calcium‐saturated cardiac troponin C in a cardiac troponin C/troponin I complex. Nuclear magnetic resonance spectroscopy and [15N,2H]cardiac troponin C permitted the mapping of bepridil‐induced amide proton chemical shifts. A single bepridil‐binding site in the regulatory domain was found with an affinity
Abusamhadneh, Ekram +5 more
openaire +4 more sources
Rotational and Translational Motion of Troponin C
Time resolved fluorescence anisotropy and sedimentation velocity has been used to study the rotational and translational hydrodynamic behavior of two mutants of chicken skeletal troponin C bearing a single tryptophan residue at position 78 or 154 in the metal-free-, metal-bound-, and troponin I peptide (residues 96-116 of troponin I)-ligated states ...
M C, Moncrieffe +6 more
openaire +4 more sources
Development of a sensitive immunosensor for the detection of cardiac Troponin T in cardiovascular disease [PDF]
Cardiovascular disease (CVD) is currently globally the biggest cause of mortality, with rising figures, especially now in the developing world. Early and accurate diagnosis of CVD, (especially acute myocardial infarction (AMI) is important in being able ...
Pawula, Maria
core +7 more sources
Interaction between troponin I and troponin C [PDF]
The spatial proximity on the surface of troponin C for sites specific for peptides CN4 (res. 96–116) and CN5 (res. 1–21) of troponin I has been demonstrated by proton magnetic resonance spectroscopy. The broadened signals from each peptide are at similar radial distances from the paramagnetic spin label bound to Cys 98 of troponin C.
Dalgarno, D.C. +5 more
openaire +2 more sources
Aluminum fluoride interactions with troponin C [PDF]
The increasing interest in the metal ion aluminum fluoride and beryllium fluoride complexes as phosphate analogs in the myosin ATPase reaction and in muscle fiber studies prompted the examination of their interactions with the regulatory system of troponin and tropomyosin.
Phan, B.C., Reisler, E.
openaire +3 more sources
Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis. [PDF]
BACKGROUND: Elevated serum cardiac troponin T (cTnT) and I (cTnI) can occur in patients with chronic kidney disease. Differences in cTn concentrations between cTnT and cTnI have been reported but the mechanism of such discrepancy has not been ...
Collinson, PO +5 more
core +1 more source
Effects of temperature and method of heat treatment on myofibrillar proteins of pork [PDF]
During the tests in this paper, meat processing was carried out at different temperatures between the range of 51°C to 100°C. The meat was processed by dry heat (roasting) and wet heat treatments (cooking) in water at atmospheric pressure. After
Vujadinović Dragan +3 more
doaj +1 more source
The Effect of High-Dose Vitamin C on Biochemical Markers of Myocardial Injury in Coronary Artery Bypass Surgery [PDF]
Objective: To evaluate the effect of high-dose vitamin C on cardiac reperfusion injury and plasma levels of creatine kinase-muscle/brain (CK-MB), troponin I, and lactate dehydrogenase (LDH) in patients undergoing coronary artery bypass grafting (CABG ...
Nafiseh Emadi +3 more
doaj +1 more source
Elevated serum levels of cardiac troponin and C-reactive protein are associated with all-cause and cardiovascular mortality in patients with end-stage renal disease.
Wei-Jie Li +6 more
doaj +1 more source

