Physical limits on computation by assemblies of allosteric proteins [PDF]
, 2008 Assemblies of allosteric proteins, nano-scale Brownian computers, are the principle information processing devices in biology. The troponin C-troponin I (TnC-TnI) complex, the Ca$^{2+}$-sensitive regulatory switch of the heart, is a paradigm for Brownian computation.
arxiv +1 more source
Biochemistry, 2010 The calcium-dependent interactions between troponin C (TnC) and other thin and thick filament proteins play a key role in the regulation of cardiac muscle contraction.
S. Tikunova +6 more
semanticscholar +1 more source
Korelasi Kadar Gamma-Glutamyl Transferase, C-Reactive Protein, dan Asam Urat dengan Troponin I [PDF]
, 2016 atar belakang : Infark miokard akut (IMA) merupakan penyebab utama kematian di dunia. Peningkatan kadar gamma-glutamyl transferase (GGT) serum terlibat dalam patogenesis penyakit arteria koroner.
Diniyah, Noor
core
Deep learning-enhanced chemiluminescence vertical flow assay for high-sensitivity cardiac troponin I testing [PDF]
Small (2025)Democratizing biomarker testing at the point-of-care requires innovations that match laboratory-grade sensitivity and precision in an accessible format. Here, we demonstrate high-sensitivity detection of cardiac troponin I (cTnI) through innovations in chemiluminescence-based sensing, imaging, and deep learning-driven analysis.
arxiv +1 more source
Journal of Biological Chemistry, 2010 In this study we explore the mechanisms by which a double mutation (E59D/D75Y) in cardiac troponin C (CTnC) associated with dilated cardiomyopathy reduces the Ca2+-activated maximal tension of cardiac muscle. Studying the single mutants (i.e.
David Dweck +3 more
semanticscholar +1 more source
The isolation of differentially expressed cDNA clones from the filarial nematode Brugia pahangi [PDF]
, 1999 A cDNA library constructed from 3 day post-infective L3 of the filarial nematode Brugia pahangi was screened by differential hybridization with cDNA probes prepared from different life-cycle stages.
Devaney, E. +4 more
core +1 more source
Clinical prediction system of complications among COVID-19 patients: a development and validation retrospective multicentre study [PDF]
arXiv, 2020 Existing prognostic tools mainly focus on predicting the risk of mortality among patients with coronavirus disease 2019. However, clinical evidence suggests that COVID-19 can result in non-mortal complications that affect patient prognosis. To support patient risk stratification, we aimed to develop a prognostic system that predicts complications ...
arxiv
Prognostic value of troponins in acute coronary syndrome depends upon patient age [PDF]
, 2014 Peer ...
Bachmann, M. O. +5 more
core +1 more source
Roles of the troponin isoforms during indirect flight muscle development in Drosophila [PDF]
, 2014 Troponin proteins in cooperative interaction with tropomyosin are responsible for controlling the contraction of the striated muscles in response to changes in the intracellular calcium concentration.
Kumar, Prabodh +3 more
core
Deep learning-enhanced paper-based vertical flow assay for high-sensitivity troponin detection using nanoparticle amplification [PDF]
ACS Nano (2024)Successful integration of point-of-care testing (POCT) into clinical settings requires improved assay sensitivity and precision to match laboratory standards. Here, we show how innovations in amplified biosensing, imaging, and data processing, coupled with deep learning, can help improve POCT.
arxiv +1 more source