Results 51 to 60 of about 162,145 (312)

Blood C‐peptide concentration as a proxy marker of cardiovascular disease: An observational cross‐sectional study

open access: yesHealth Science Reports, 2023
Background and Aims Cardiovascular diseases (CVDs) are among the leading causes of disability and early death in sub‐Saharan Africa. Most of the current blood tests for CVD diagnosis involve performing about three test profiles; often at additional cost ...
Laurinda Adusu‐Donkor   +8 more
doaj   +1 more source

Development of Optical Biosensor Technologies for Cardiac Troponin Recognition [PDF]

open access: yes, 2015
Acute myocardial infarction (AMI) is the leading cause of death among cardiovascular diseases. Among the numerous attempts to develop coronary marker concepts into clinical strategies, cardiac troponin is known as a specific marker for coronary events ...
Abdolrahim, Mojgan   +5 more
core   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum   +5 more
wiley   +1 more source

Impact of copeptin on diagnosis of acute coronary syndrome

open access: yesEgyptian Journal of Medical Human Genetics, 2014
Background: Acute coronary syndrome remains the principal cause of death, so the early diagnosis is of great importance. Cardiac troponin is the preferred biomarker for acute myocardial infarction.
Zeinab H. El Sayed   +4 more
doaj   +1 more source

Extracellular Vesicle cystatin c is associated with unstable angina in troponin negative patients with acute chest pain.

open access: yesPLoS ONE, 2020
BackgroundDespite the use of high-sensitive cardiac troponin there remains a group of high-sensitive cardiac troponin negative patients with unstable angina with a non-neglectable risk for future adverse cardiovascular events, emphasising the need for ...
Mirthe Dekker   +10 more
doaj   +1 more source

Serum troponin, D‐dimer, and CRP level in severe coronavirus (COVID‐19) patients

open access: yesImmunity, Inflammation and Disease, 2022
Background Abnormal inflammation coagulation biomarker levels of troponin, C‐reactive protein (CRP), and D‐dimer levels in serum have been demonstrated to be associated and involved in the disease progression of coronavirus disease 2019 (COVID‐19 ...
Ayad M. Ali   +5 more
doaj   +1 more source

NMR analysis of cardiac troponin C‐troponin I complexes: effects of phosphorylation [PDF]

open access: yesFEBS Letters, 1999
Phosphorylation of the cardiac specific amino‐terminus of troponin I has been demonstrated to reduce the Ca2+ affinity of the cardiac troponin C regulatory site. Recombinant N‐terminal cardiac troponin I proteins, cardiac troponin I(33–80), cardiac troponin I(1–80), cardiac troponin I(1–80)DD and cardiac troponin I(1–80)pp, phosphorylated by protein ...
Finley, Natosha   +10 more
openaire   +3 more sources

Influence of case definition on incidence and outcome of acute coronary syndromes [PDF]

open access: yes, 2016
© 2016, BMJ Publishing Group. All rights reserved. Objective: Acute coronary syndromes (ACS) are common, but their incidence and outcome might depend greatly on how data are collected.
Alamgir, Farqad   +11 more
core   +2 more sources

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

The importance of intrinsically disordered segments of cardiac troponin in modulating function by phosphorylation and disease-causing mutations

open access: yesFrontiers in Physiology, 2016
Troponin plays a central role in regulation of muscle contraction. It is the Ca2+ switch of striated muscles including the heart and in the cardiac muscle is physiologically modulated by PKA-dependent phosphorylation at Ser22 and 23.
Maria Papadaki, Steven Baxter Marston
doaj   +1 more source

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