Results 61 to 70 of about 19,854,960 (401)

Biosensors for cardiac biomarkers detection: a review [PDF]

, 2012
The cardiovascular disease (CVD) is considered as a major threat to global health. Therefore, there is a growing demand for a range of portable, rapid and low cost biosensing devices for the detection of CVD.
Gurbuz, Yasar, Gürbüz, Yaşar, Kolkar Mohammed, Javed Hussain Niazi, Qureshi, Anjum   +3 more
core   +1 more source

Tapered Pillar Design for High‐Precision Force Readout in Miniaturized Engineered Heart Tissues From Human Pluripotent Stem Cells

Advanced Healthcare Materials, EarlyView.
Engineered heart tissues (EHTs) are a valuable approach in capturing human cardiac physiology and drug responses in vitro. Here, a novel tapered pillar design is developed in an EHT platform to confine tissues in a predefined position‐ at the middle of the pillar height.
Milica Dostanić, Maury Wiendels, Laura M. Windt, Mervyn P.H. Mol, Francijna E. van den Hil, Richard P. Davis, Valeria Orlova, Berend J. van Meer, Massimo Mastrangeli, Christine L. Mummery   +9 more
wiley   +1 more source

A computational exploration of the interactions of the green tea polyphenol (-)-Epigallocatechin 3-Gallate with cardiac muscle troponin C.

PLoS ONE, 2013
Thanks to its polyphenols and phytochemicals, green tea is believed to have a number of health benefits, including protecting from heart disease, but its mechanism of action at the molecular level is still not understood.
Dominic Botten, Giorgia Fugallo, Franca Fraternali, Carla Molteni   +3 more
doaj   +1 more source

Robust pH Sensing Using a Graphene Oxide and Covalent Organic Frameworks Composite for Gastro‐esophageal Reflux Disease Diagnosis

Advanced Healthcare Materials, EarlyView.
A stable composite pH sensor is developed by coating graphene oxide (GO) nanosheets with covalent organic frameworks (COFs) to improve stability and sensitivity in acidic environments. The GO/COFs sensor demonstrates high selectivity, linearity, and biocompatibility, offering a promising strategy for continuous pH monitoring in gastro‐esophageal reflux
Ahmed H. M. Salem, Jianhui Zhang, Ashley Lam, Haowei Wang, Umber Cheema, Laurence B. Lovat, Manish K. Tiwari   +6 more
wiley   +1 more source

Blood C‐peptide concentration as a proxy marker of cardiovascular disease: An observational cross‐sectional study

Health Science Reports, 2023
Background and Aims Cardiovascular diseases (CVDs) are among the leading causes of disability and early death in sub‐Saharan Africa. Most of the current blood tests for CVD diagnosis involve performing about three test profiles; often at additional cost ...
Laurinda Adusu‐Donkor, Emmanuel Kwaku Ofori, Fleischer C. N. Kotey, Francis Kwaku Dogodzi, Wormenor Dziedzorm, Alfred Buabeng, Segla Kwame Bernard, Seth K. Amponsah, Henry Asare‐Anane   +8 more
doaj   +1 more source

Vascularized and Perfusable Human Heart‐on‐a‐Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery

Advanced Materials, EarlyView.
This novel 3D human ischemic heart‐on‐a‐chip, with perfusable vasculature directly interfaced with myocardial tissue, replicates key aspects of ischemic heart injury. It also demonstrates the targeted delivery and therapeutic efficacy of cardiac homing peptide‐conjugated liposomes, validating the platform for drug and nanomedicine screening in ...
Junyoung Kim, Xuening Zhang, Richard Wang, Adrian Najer, Qiao You Lau, Ana Cammack‐Najera, Jang Ah Kim, Yoo Kyung Kang, Ruoxiao Xie, Hyemin Kim, Kai Xie, Hyeonji Lim, Tae‐Eun Park, Jinmyoung Joo, Molly M. Stevens   +14 more
wiley   +1 more source

Impact of copeptin on diagnosis of acute coronary syndrome

Egyptian Journal of Medical Human Genetics, 2014
Background: Acute coronary syndrome remains the principal cause of death, so the early diagnosis is of great importance. Cardiac troponin is the preferred biomarker for acute myocardial infarction.
Zeinab H. El Sayed, Hala A. Mahmoud, Layla Y. El Shall, Fawzia A. El Sheshtawey, Manal A. Mohamed   +4 more
doaj   +1 more source

Serum troponin, D‐dimer, and CRP level in severe coronavirus (COVID‐19) patients

Immunity, Inflammation and Disease, 2022
Background Abnormal inflammation coagulation biomarker levels of troponin, C‐reactive protein (CRP), and D‐dimer levels in serum have been demonstrated to be associated and involved in the disease progression of coronavirus disease 2019 (COVID‐19 ...
Ayad M. Ali, Hassan M. Rostam, Mohammed H. Fatah, Chalak M. Noori, Kameran M. Ali, Hassan M. Tawfeeq   +5 more
doaj   +1 more source

Engineered Plasmonic and Fluorescent Nanomaterials for Biosensing, Motion, Imaging, and Therapeutic Applications

Advanced Materials, EarlyView.
A schematic illustration of how noble metals can be used to create nanoparticles (NPs) or nanoclusters (NCs). Noble metal NPs, due to their plasmonic properties, enable photothermal therapy and surface‐enhanced Raman scattering (SERS). In contrast, NCs, which lack a plasmonic resonance band, exhibit fluorescence, making them ideal for bioimaging ...
David Esporrín‐Ubieto, Juan C. Fraire, Daniel Sánchez‐deAlcázar, Samuel Sánchez   +3 more
wiley   +1 more source

The importance of intrinsically disordered segments of cardiac troponin in modulating function by phosphorylation and disease-causing mutations

Frontiers in Physiology, 2016
Troponin plays a central role in regulation of muscle contraction. It is the Ca2+ switch of striated muscles including the heart and in the cardiac muscle is physiologically modulated by PKA-dependent phosphorylation at Ser22 and 23.
Maria Papadaki, Steven Baxter Marston
doaj   +1 more source