Results 101 to 110 of about 6,673,815 (394)

THE ROLE OF OBESITY IN THE DEVELOPMENT OF INFLAMMATION AND PROGRESSION OF HEART FAILURE IN CORONAVIRUS DISEASE

open access: yesМедична наука України, 2022
Relevance. Tissue plays a complex physiological role and may therefore progress to COVID-19 and heart failure. Objective is to evaluate the definition and myocardial biomarkers in a patient with viral disease in combination with obesity and heart ...
O.O. Samchuk   +2 more
doaj   +1 more source

Deep learning-enhanced chemiluminescence vertical flow assay for high-sensitivity cardiac troponin I testing [PDF]

open access: yesSmall (2025)
Democratizing biomarker testing at the point-of-care requires innovations that match laboratory-grade sensitivity and precision in an accessible format. Here, we demonstrate high-sensitivity detection of cardiac troponin I (cTnI) through innovations in chemiluminescence-based sensing, imaging, and deep learning-driven analysis.
arxiv   +1 more source

A Rado theorem for complex spaces [PDF]

open access: yesarXiv, 2021
We generalize Rado's extension theorem to complex spaces.
arxiv  

Expression of the fast twitch troponin complex, fTnT, fTnI and fTnC, in vascular smooth muscle.

open access: yesCell Motility and the Cytoskeleton, 2008
It is generally believed that proteins of the troponin complex are not expressed in smooth muscle. We have directly assayed for expression of troponin transcripts in mouse vascular smooth muscle and found that troponin sequences normally associated with ...
Carlos M. Moran   +5 more
semanticscholar   +1 more source

Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly

open access: yesAdvanced Science, EarlyView.
Berberine, a safe and FDA‐approved drug, is identified as a novel mitochondrial calcium uniporter (MCU) inhibitor. By disrupting MCU‐EMRE interaction, Berberine prevents mitochondrial calcium overload and protects against ischemia/reperfusion injury, offering a promising therapeutic strategy for diseases linked to mitochondrial calcium dysregulation ...
Haixin Zhao   +17 more
wiley   +1 more source

Clinical prediction system of complications among COVID-19 patients: a development and validation retrospective multicentre study [PDF]

open access: yesarXiv, 2020
Existing prognostic tools mainly focus on predicting the risk of mortality among patients with coronavirus disease 2019. However, clinical evidence suggests that COVID-19 can result in non-mortal complications that affect patient prognosis. To support patient risk stratification, we aimed to develop a prognostic system that predicts complications ...
arxiv  

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao   +19 more
wiley   +1 more source

The impact of electroconvulsive therapy on the spatial QRS-T angle and cardiac troponin T concentration in psychiatric patients.

open access: yesPLoS ONE, 2019
BACKGROUND:Electroconvulsive therapy (ECT) is an effective treatment method used in psychiatry; however, its cardiac safety has not been clearly demonstrated.
Michał Próchnicki   +4 more
doaj   +1 more source

Filament compliance influences cooperative activation of thin filaments and the dynamics of force production in skeletal muscle. [PDF]

open access: yesPLoS Computational Biology, 2012
Striated muscle contraction is a highly cooperative process initiated by Ca²⁺ binding to the troponin complex, which leads to tropomyosin movement and myosin cross-bridge (XB) formation along thin filaments. Experimental and computational studies suggest
Bertrand C W Tanner   +2 more
doaj   +1 more source

Oriented Getzler-Kapranov complexes and framed curves [PDF]

open access: yesarXiv, 2022
In the present paper, we introduce and study oriented Getzler-Kapranov complexes. These complexes are generalizations of S. Merkulov's oriented graph complex. We investigate their relation to the cohomology of moduli spaces of complex and tropical curves, ribbon graph complexes, and motivic structures in string topology.
arxiv  

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