The cardiac wound healing response to myocardial infarction
WIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023 Cardiac wound healing after myocardial infarction is a balance between the breakdown of existing and the construction of new extracellular matrix, with inflammation feeding into both sides. Abstract Myocardial infarction (MI) is defined as evidence of myocardial necrosis consistent with prolonged ischemia.
Upendra Chalise +2 more
wiley +1 more source
Equilibrium Blocking Model of Isometric Tension [PDF]
arXiv, 2009 Calcium activation of striated muscle is known to exhibit a strongly cooperative dependency on calcium. Because the calcium receptor protein, troponin (Tn) is known to bind calcium non-cooperatively and has yet to be linked to a cooperative change in the myosin-blocking protein, tropomyosin (Tm), we describe a model in which cooperativity is ...
arxiv
Cardiac damage biomarkers and heart rate variability following a 118-km mountain race: relationship with performance and recovery [PDF]
, 2019 This study aimed to assess the release of cardiac damage biomarkers jointly with cardiac autonomic modulation after a mountain ultramarathon. Such knowledge and the possible relationship of these markers with race time is of primary interest to establish
Collado-Boira, Eladio +4 more
core +1 more source
The meaning of different forms of structural myocardial injury, immune response and timing of infarct necrosis and cardiac repair [PDF]
, 2015 Although a decline in the all-cause and cardiac mortality rates following myocardial infarction (MI) during the past 3 decades has been reported, MI is a major cause of death and disability worldwide.
Bello, S +5 more
core +1 more source
JACC: Basic to Translational Science, 2016 Poloxamer 188 (P188) is a nonionic triblock copolymer believed to prevent cellular injury after ischemia and reperfusion. This study compared intracoronary (IC) infusion of P188 immediately after reperfusion with delayed infusion through a peripheral ...
Jason A. Bartos, MD, PhD +11 more
doaj +1 more source
Intermolecular And Dynamic Investigation of The Mechanism of Action of Reldesemtiv on Fast Skeletal Muscle Troponin Complex Toward the Treatment of Impaired Muscle Function. [PDF]
Protein J, 2023 Issahaku AR +3 more
europepmc +1 more source
Plasma proteomic signature of decline in gait speed and grip strength
Aging Cell, Volume 21, Issue 12, December 2022., 2022 Several plasma proteins were associated with physical function decline in adults from middle to older age, including GDF‐15, pleiotrophin, and TIMP‐1 for gait speed decline, and CA III, CDON, and SMOC1 for grip strength decline. These novel proteomic biomarkers may by explored as future mechanisms and targets for age‐related functional decline ...
Xiaojuan Liu +11 more
wiley +1 more source
Evaluation of cardiac markers and some serumic biochemical parameters in seropositive horses with equine influenza [PDF]
Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2013 This study was performed to evaluate the effect of influenza in horses on the electrocardiogram changes, cardiac arrhythmias and concentration of cardiac troponin in serum and serumic activity of some enzymes.
ali hassanpour +2 more
doaj
A metabolite-sensitive, thermodynamically-constrained model of\ud cardiac cross-bridge cycling: Implications for force development during ischemia [PDF]
, 2009 We present a metabolically regulated model of cardiac active force generation with which we investigate the effects of ischemia on maximum forceproduction. Our model, based on the Rice et al.
Crampin, E. J. +3 more
core +2 more sources
Drug Testing and Analysis, EarlyView.The metabolism and urinary elimination of two substances recently classified as prohibited substances in sport was conducted, yielding suitable target analytes for efficient doping controls employing routinely applied chromatographic‐mass spectrometric test methods.
Luisa Euler +4 more
wiley +1 more source