Results 171 to 180 of about 5,264,822 (290)

Fifth Universal Definition of Myocardial Infarction (2026): On behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and the Society of Thoracic Surgeons (STS) Affirmation of Value by the Society for Cardiovascular Angiography and Interventions (SCAI). [PDF]

Glob Heart
Mills NL, Newby LK, Zaman S, Almahmeed WA, Bucciarelli-Ducci C, Colvin MM, Dangas GD, DeVon HA, Dharmakumar R, Gaziano TA, Hausenloy DJ, Jeilan M, Koskinas KC, Lindahl B, Motovska Z, Gimenez MR, Salvati AM, Tamis-Holland JE, ESC/ACC/AHA/WHF Universal Definition Document Advisory Group.   +18 more
europepmc   +1 more source

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

The FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan, Jafar S. Jabbari, Naomi X. L. Ling, Anne M. Kong, Jia Q. Truong, Marnie L. Maddock, Ayeshah A. Rosdah, Christopher G. Langendorf, Lifang Zhang, Jarmon G. Lees, Sebastian Bass‐Stringer, Danise Ann Onda, Alice Pébay, Mirella Dottori, Kim Loh, Jessica K. Holien, Sean Lal, Nadia M. Davidson, Jonathan S. Oakhill, Shiang Y. Lim   +19 more
wiley   +1 more source

Role of FibroScan in evaluating hepatic involvement in systemic amyloidosis: a single‐centre prospective pilot study

Internal Medicine Journal, EarlyView.
Abstract Background Amyloidosis encompasses a group of diseases characterised by extracellular deposition of misfolded protein fibrils, potentially leading to organ dysfunction. Liver involvement occurs via direct amyloid infiltration, common in immunoglobulin light chain (AL) amyloidosis, or congestive hepatopathy, more typical in transthyretin (ATTR)
M Tang, N Vootukuru, J Tjahyadi, D Clayton Chubb, H Jina, SB Ting, S Bloom, R Sawhney, S Gibbs, O. Niewiadomski   +9 more
wiley   +1 more source

The detection of cardiovascular biomarkers in dermal interstitial fluid - a step to real-time monitoring. [PDF]

Front Cardiovasc Med
Bhatti Y, Yazdi A, Jones DA, Locca D, Vadgama P, Ionescu AM, Mathur A.   +6 more
europepmc   +1 more source

Trajectory of macrotroponin in a community cohort

Internal Medicine Journal, EarlyView.
Abstract Background Cardiac troponin I (cTnI) is a biomarker for myocardial injury. However, macrotroponin, a complex of cTnI and endogenous cardiac troponin autoantibodies, may artefactually elevate cTnI levels with potential to mislead clinicians, leading to inappropriate investigation and management.
Duncan J. Campbell, Fei Fei Gong, Michele McGrady, David L. Prior, Christopher M. Reid, Christina M. Trambas   +5 more
wiley   +1 more source

Does increasing model complexity improve HEART-based chest pain risk stratification? A multicentre development and held-out emergency department validation study. [PDF]

Open Heart
Wang H, Williamson JR, Scarborough H, Sandlin D.   +3 more
europepmc   +1 more source

Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025)

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT With the accelerating population aging, the number of older adult patients with lung cancer continues to increase. These patients often present with multiple chronic diseases and geriatric syndromes, resulting in more complex perioperative management and significantly increased surgical risks.
Daiping Li, Rui Liang, Birong Dong, Lunxu Liu, Ning Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +6 more
wiley   +1 more source

Inflammatory Hot Phases in Arrhythmogenic Cardiomyopathy: A Dynamic Electrophysiologic Substrate Beyond Scar. [PDF]

JACC Adv
Zarghami M, Maleki ND, Naddaf S, Abdulhadi T, Grabos M, Kanan A, Osser D, Mahdavinia A, Gulati S, Singh A.   +9 more
europepmc   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Cardiac Myosin-Binding Protein C in Suspected Acute Coronary Syndrome: From Sarcomeric Injury Biology to Decision-Grade Risk Stratification. [PDF]

Int J Mol Sci
Pruc M, Maslyk M, Jaguszewski MJ, Szarpak L.   +3 more
europepmc   +1 more source