Results 191 to 200 of about 5,264,822 (290)

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li   +19 more
wiley   +1 more source

A Forensic Approach to Perioperative Deaths After Non-Cardiac Surgery: A Narrative Review. [PDF]

open access: yesDiagnostics (Basel)
Tattoli L   +5 more
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

When NCX switches sides: Experimental and computational insights into Ca2+ regulation in the heart

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Due to its presence inside the dyadic cleft, Na+/Ca2+ exchanger (NCX) builds a functional unit together with L‐type calcium channels and ryanodine receptors in the dyadic cleft. NCX acts bidirectionally (forward and reverse mode) dependent on extracellular calcium ([Ca2+]o) and sodium ([Na+]o) concentrations and the membrane ...
Wilhelm Neubert   +6 more
wiley   +1 more source

Relationship Between Salivary and Serum Cardiac Troponin I in Patients Undergoing Cardiac Surgery: A Prospective Longitudinal Observational Study. [PDF]

open access: yesDiagnostics (Basel)
Mrkonjić R   +8 more
europepmc   +1 more source

Restoration of neuromuscular function by mitochondrial transplantation in injured mouse skeletal muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mice received chemical injury (cardiotoxin) in the tibialis anterior muscle of one limb, and the contralateral muscle was injected with phosphate‐buffered saline (PBS) as a sham control. Mice then received PBS or mitochondria suspended in PBS into the tail vein.
Stephen E. Alway   +6 more
wiley   +1 more source

Impact of noradrenaline, adrenergic receptors, and radical formation on cardiac mitochondria in resuscitated swine. [PDF]

open access: yesIntensive Care Med Exp
Abele N   +22 more
europepmc   +1 more source

Cardiovascular Toxicity Associated With Bispecific Antibodies in Hematological Malignancies: A Comprehensive Pharmacovigilance Analysis

open access: yesAmerican Journal of Hematology, Volume 101, Issue 10, Page 2546-2556, October 2026.
ABSTRACT Cardiovascular adverse events (CVAEs) associated with bispecific T‐cell engaging antibodies (BsAbs) have not been systematically investigated across approved agents. In this disproportionality analysis of FAERS (December 2014–September 2025), reports listing BsAbs as the primary suspected drug (n = 7647) were compared with all other drugs in ...
Malak Munir   +9 more
wiley   +1 more source

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