Results 181 to 190 of about 6,764,388 (368)

Electrochemical Biosensors Designed with Coordination Compounds: Recent Advancements and Future Perspectives

ECS Sensors Plus
Electrochemical (EC) biosensors based on coordination compounds have risen as an impeccable way to detect biological moieties due to their cogent results.
Abhay Nanda Srivastva, Kriti Milan, Netra Pal Singh, Dharm Veer Singh, Manish Kumar, Vishal Chaudhary, Samiksha Dabas   +6 more
doaj   +1 more source

Revealing the Diverse Allergenic Protein Repertoire of Six Widely Consumed Crab Species: A Species‐Specific Allergen in King Crab

Allergy, EarlyView.
This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li, Jingyuan Bian, Qing Xiong, Brian Shing‐Hei Wong, Stephen Kwok‐Wing Tsui, Kin‐Ming Kwan, Nicki Yat‐Hin Leung, Ting‐Fan Leung, Patrick S. C. Leung, Ka‐Hou Chu, Xiaojun Xiao, Christine Yee‐Yan Wai   +11 more
wiley   +1 more source

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

British Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig, Yusuf C. Erdoğan, Benjamin Gottschalk, Michael Gruber, Andrea Groselj‐Strele, Sandra Burgstaller, Wolfgang F. Graier, Roland Malli   +7 more
wiley   +1 more source

Transcriptional and functional effects of mavacamten in multiple porcine and human models with hypertrophic cardiomyopathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Mavacamten (MAVA) is a novel small molecule inhibitor of cardiac myosin, mitigating cardiomyocyte hypercontractility in patients with hypertrophic obstructive cardiomyopathy (HOCM). Despite its recent approval for clinical use, the transcriptional and functional impacts of MAVA remain not well understood.
Elisa Kiselev, Wilson Agyapong, Bjarne Jürgens, Elisa Mohr, Shambhabi Chatterjee, Hannah J. Hunkler, Jawad Salman, Giuseppe Cipriano, Marco Bentele, Junqing Liu, Jonas Specht, Kaja S. Menge, Florian J. G. Waleczek, Jonas A. Haas, Anselm A. Derda, Kristina Sonnenschein, Anika Gietz, Susanne Neumüller, Angelika Pfanne, Oliver Beetz, Michael Pflaum, Bettina Wiegmann, Yiangos Psaras, Christopher Toepfer, Robert Zweigerdt, Ante Radocaj, Theresia Kraft, Andre Zeug, Evgeni Ponimaskin, Wilhelm Korte, Alexander Horke, Arjang Ruhparwar, Maximilian Fuchs, Ke Xiao, Christian Bär, Natalie Weber, Thomas Thum   +36 more
wiley   +1 more source

Interaction of cardiac leiomodin with the native cardiac thin filament.

PLoS Biology
Every heartbeat depends on cyclical contraction-relaxation produced by the interactions between myosin-containing thick and actin-based thin filaments (TFs) arranged into a crystalline-like lattice in the cardiac sarcomere.
Madison Little, Cristina M Risi, Tania M Larrinaga, Mason D Summers, Tyler Nguyen, Garry E Smith, Jennifer Atherton, Carol C Gregorio, Alla S Kostyukova, Vitold E Galkin   +9 more
doaj   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Infective Endocarditis Complicated by Severe Mitral Regurgitation and Markedly Elevated Troponin Levels as A Prognostic Marker: A Case Report

Research Reports in Clinical Cardiology
Osman Farah Dahir, Mohamed Omar Hassan, Ahmed Shafie Adan, Ahmed Elmi Abdi, Ishak Ahmed Abdi Cardiology Department, Mogadishu Somali-Türkiye Training and Research Hospital, Mogadishu, SomaliaCorrespondence: Osman Farah Dahir, Department of Cardiology ...
Dahir OF, Hassan MO, Adan AS, Abdi AE, Abdi IA   +4 more
doaj  

Cardiac arrhythmia prevalence and risk factors in 24‐h electrocardiograms of sedentary horses

Equine Veterinary Journal, EarlyView.
Abstract Background Cardiac arrhythmias are common in horses, but their clinical relevance remains controversial. Objectives To describe prevalence and identify risk factors for arrhythmias that may warrant additional screening in a sedentary mixed‐breed population of horses. Study Design Prospective cross‐sectional.
Lauren T. Maas, Elizabeth Williams Louie, Carrie J. Finno, Callum G. Donnelly, Joshua A. Stern, Ashley E. Hill, Jessica M. Morgan   +6 more
wiley   +1 more source

When Delirium Unmasks a Silent Myocardial Infarction

Journal of the American Geriatrics Society, EarlyView.
Abbreviations: hs‐TnT: high sensitivity Troponin T; STEMI: ST‐elevation myocardial infarction.
Eugenia Casali, Wenxiang Guo, Eleonora Cucini, Francesca Pisani, Alberto Finazzi, Maria Cristina Ferrara, Maurizio Corsi, Elena Pinardi, Chukwuma Okoye, Paolo Mazzola, Giuseppe Bellelli   +10 more
wiley   +1 more source

Myocardial Infarction in Conduction System Pacing: Trust the ECG or Rely on Algorithms?

Pacing and Clinical Electrophysiology, EarlyView.
Abstract A 66‐year‐old male patient with a conduction system pacing (CSP) pacemaker, implanted after a pace‐and‐ablate strategy for persistent, poorly rate‐controlled atrial fibrillation, presented to the outpatient clinic with worsening dyspnea. Laboratory findings and ECG were indicative of an anterolateral ST‐segment elevation myocardial infarction (
Elena Crisman, Alexandra‐Maria Neagoe, Andreas Haeberlin, Jonas Häner, Bruno Schnegg   +4 more
wiley   +1 more source