In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai+22 more
wiley +1 more source
Cardiac Troponin as a Prognostic Indicator for Major Adverse Cardiac Events in Non-Cardiac Surgery: A Narrative Review. [PDF]
Sayed Masri SNN+3 more
europepmc +1 more source
A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex [PDF]
Ian M. Robertson+3 more
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Cardioprotective effects of the extracellular chaperone clusterin in acute myocardial infarction
In vivo, CLU−/− mice were more susceptible to acute myocardial infarction than CLU+/+ mice. Moreover, inflammation and histone levels were significantly increased in CLU−/− mice compared to CLU+/+ mice following ischemia/reperfusion. In vitro, CLU protects cardiomyocytes from histone‐ and/or hypoxia‐induced cell death.
Louwana Allawa+12 more
wiley +1 more source
Takotsubo Cardiomyopathy With an Unusually High Troponin Level Post-laparotomy for Small Bowel Obstruction Secondary to Adhesions in a Patient Presenting With Pelvic Inflammatory Disease. [PDF]
Khan AZ, Jayawardena UA, Luke D.
europepmc +1 more source
Solution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: The basis of W7 as an inhibitor of cardiac muscle contraction [PDF]
Marta Oleszczuk+3 more
openalex +1 more source
Cardiac Troponin I Biosensors: Innovations in Real-Time Diagnosis of Cardiovascular Diseases. [PDF]
Ebrahimi S+7 more
europepmc +1 more source
A loss of function TNNT1 myopathy mouse model with the nonsense mutation p.E180* showed potential cytotoxicity of the truncated slow troponin T fragment. The mRNA expression profile in the soleus muscle of Tnnt1‐p.E180* mice showed very different changes in comparison to that of Tnnt1‐knockout mice.
Han‐Zhong Feng+2 more
wiley +1 more source
The Role of N-terminal Pro-B-Type Natriuretic Peptide, Troponins, and D-dimer in Acute Cardio-Respiratory Syndromes: A Multi-specialty Systematic Review. [PDF]
Ibrahim M+12 more
europepmc +1 more source
Crystallization and preliminary x-ray analysis of troponin ternary complex
Shigeki Takeda+4 more
openalex +2 more sources