Impact of genotype and phenotype on cardiac biomarkers in patients with transthyretin amyloidosis - Report from the Transthyretin Amyloidosis Outcome Survey (THAOS). [PDF]
PLoS ONE, 2017 AIM:Cardiac troponins and natriuretic peptides are established for risk stratification in light-chain amyloidosis. Data on cardiac biomarkers in transthyretin amyloidosis (ATTR) are lacking.
Arnt V Kristen +6 more
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Drug-Induced Rhabdomyolysis with Elevated Cardiac Troponin T [PDF]
Case Reports in Medicine, 2015 The essential role of cardiac troponin in the diagnosis of acute myocardial infarction has led to the development of high-sensitivity assays, which are able to detect very small amounts of myocardial necrosis.
Gro Egholm, Manan Pareek
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Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T [PDF]
International Journal of Biological Sciences, 2006 Protein dephosphorylation by protein phosphatase 1 (PP1), acting in concert with protein kinase C (PKC) and protein kinase A (PKA), is a pivotal regulatory mechanism of protein phosphorylation.
Brian H Crawford +3 more
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N-Terminal Pro-B-Type Natriuretic Peptide and Cardiac Troponin T in Stable Renal Transplant Recipients and All-Cause Mortality, Cardiovascular, and Renal Events [PDF]
BiomoleculesIntroduction: In renal transplant recipients (RTRs), kidney graft failure and cardiovascular (CV) disease are prevalent and associated with mortality.
Zbigniew Heleniak +6 more
doaj +2 more sources
Multiple Species Comparison of Cardiac Troponin T and Dystrophin: Unravelling the DNA behind Dilated Cardiomyopathy [PDF]
Journal of Cardiovascular Development and Disease, 2017 Animals have frequently been used as models for human disorders and mutations. Following advances in genetic testing and treatment options, and the decreasing cost of these technologies in the clinic, mutations in both companion and commercial animals ...
Jennifer England +2 more
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Cardiac troponin T as a serum biomarker of respiratory impairment in amyotrophic lateral sclerosis [PDF]
Annals of Clinical and Translational NeurologyObjective Informative biomarkers are an urgent need in the management of amyotrophic lateral sclerosis. Serum cardiac troponin T is elevated in the majority of amyotrophic lateral sclerosis patients and increases with disease progression.
Teresa Koch +8 more
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The incidence of myocardial injury following post-operative Goal Directed Therapy [PDF]
BMC Cardiovascular Disorders, 2007 Background Studies suggest that Goal Directed Therapy (GDT) results in improved outcome following major surgery. However, there is concern that pre-emptive use of inotropic therapy may lead to an increased incidence of myocardial ischaemia and infarction.
Fawcett Jayne +5 more
doaj +7 more sources
Diagnostics, 2022 Identifying acute myocardial infarction in patients with renal disease is notoriously difficult, due to atypical presentation and chronically elevated troponin.
Jan Kampmann +6 more
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Renal Elimination of Troponin T and Troponin I [PDF]
Clinical Chemistry, 2003 Cardiovascular complications represent the predominant cause of death in patients in the terminal stage of renal failure. Increased concentrations of cardiac troponin T (cTnT) may be a valuable predictor of cardiac risk (1)(2). However, cardiac troponin I (cTnI), clinical symptoms, and electrocardiogram (ECG) indications may be absent in patients with ...
Andreas Lun +10 more
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The Prognostic Significance of Troponin I and Troponin T [PDF]
Academic Emergency Medicine, 1998 Abstract. Objectives: To determine and compare the prognostic abilities of early, single‐sample measurements of cardiac troponin I (cTn‐I), cardiac troponin T (cTn‐T), creatine kinase‐MB (CK‐MB) among ED patients with possible myocardial ischemia. Methods: Prospective collection of clinical and serologic data using an identity‐unlinked technique from
Edward S. Bessman +5 more
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