Results 271 to 280 of about 12,042,484 (342)

The Interplay of Ontogeny and Phylogeny at the Transcriptome Level of the Tetrapod Heart

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
The main stages of development during which species‐specific heart anatomy is determined in the ontogeny of representative tetrapods. Transcriptomic similarity is expected earlier in development before heart anatomy diverges. ABSTRACT The tetrapod heart is characterized by three chambers in amphibians and non‐avian reptiles, as opposed to four in birds,
G. A. Cordero, A. K. Holloway, T. Friedrich, J. Eme, W. Eckalbar, K. Kusumi, F. J. Janzen, J. W. Hicks, F. L. Conlon, B. G. Bruneau, K. S. Pollard   +10 more
wiley   +1 more source

Interpretation of elevated baseline concentrations and serial changes of high-sensitivity cardiac troponin T in confirmed muscular dystrophies. [PDF]

ESC Heart Fail
Yildirim M, Reich C, Salbach C, Pribe-Wolferts R, Milles BR, Täger T, Mueller-Hennessen M, Weiler M, Meder B, Frey N, Giannitsis E.   +10 more
europepmc   +1 more source

Elevated high-sensitive cardiac troponin T in emergency department patients: insights from a retrospective descriptive cohort study. [PDF]

Int J Emerg Med
Syryca F, Haller B, Schmid L, Kallweit C, Nicol P, Trenkwalder T, Kanz KG, Haas A, Dommasch M.   +8 more
europepmc   +1 more source

Elevated concentrations of cardiac troponin T are associated with thoracic aortic calcification in non-dialysis chronic kidney disease patients of stage G3 to G5. [PDF]

Ren Fail
Zhu W, Lai Z, Xue M, Feng S, Feng P, Pan X, Ke X, Chen X, Li Z, Mao H, Yang X, Huang F, Chen W, Xu Y, Li S, Guo Q.   +15 more
europepmc   +1 more source

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

Molecular Nutrition &Food Research, EarlyView.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang, Michelle Lee, Erika de Jesus, Katherine Weh, Connor Howard, Henriette Remmer, Amy B. Howell, Laura A. Kresty   +7 more
wiley   +1 more source

Kidney function-specific cut-off values of high-sensitivity cardiac troponin T for the diagnosis of acute myocardial infarction. [PDF]

Clin Kidney J
Chen R, Pang M, Yu H, Luo F, Zhang X, Su L, Li Y, Zhou S, Xu R, Gao Q, Gan D, Xu X, Nie S, Hou FF, CRDS study Investigators .   +14 more
europepmc   +1 more source

A Phase 1, Double‐Blind, Placebo‐Controlled Trial of Sevasemten (EDG‐5506), a Selective Modulator of Fast Skeletal Muscle Contraction, in Healthy Volunteers and Adults With Becker Muscular Dystrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Sevasemten (EDG‐5506) is an orally administered, investigational small molecule that selectively modulates fast muscle fiber contraction by inhibiting fast myosin ATPase. This study assessed the safety, tolerability, and pharmacokinetics (PK)/pharmacodynamics (PD) of sevasemten in healthy adult volunteers (HVs) and adults ...
Joanne Donovan, Jeffrey A. Silverman, Ben Barthel, Michael DuVall, Molly Madden, James MacDougall, Nicole Rempel Kilburn, Abby Bronson, Marc Evanchik, Gilad Gordon, Kevin Koch, Alan J Russell   +11 more
wiley   +1 more source

The Role of N-Terminal-Pro-B-Type Natriuretic Peptide (NT-proBNP) and High-Sensitivity Troponin T (Hs-Troponin T) in the Evaluation of the Syntax Score in Patients With Acute Coronary Syndrome. [PDF]

Cureus
Ho AB, Tran QB.
europepmc   +1 more source

Serum Cardiac Troponin T Levels as a Therapy Response Marker in Tofersen‐Treated ALS

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Cardiac troponin T (cTnT) levels are elevated in the majority of persons with amyotrophic lateral sclerosis (ALS) and increase over time. Neurofilament light chain (NfL) is an established therapy response biomarker in ALS as superoxide dismutase1 (SOD1)‐ALS patients treated with the antisense oligonucleotide tofersen show a ...
Sarah Bernsen, Rachel Fabian, Yasemin Koc, Peggy Schumann, Peter Körtvélyessy, Sergio Castro‐Gomez, Thomas Meyer, Patrick Weydt   +7 more
wiley   +1 more source

Long-term prognosis of low high-sensitivity cardiac troponin T in the emergency department compared with the general population. [PDF]

Heart
Cyon L, Kadesjö E, Edgren G, Roos A.
europepmc   +1 more source