The Prognostic Significance of Troponin I and Troponin T [PDF]
Abstract. Objectives: To determine and compare the prognostic abilities of early, single‐sample measurements of cardiac troponin I (cTn‐I), cardiac troponin T (cTn‐T), creatine kinase‐MB (CK‐MB) among ED patients with possible myocardial ischemia. Methods: Prospective collection of clinical and serologic data using an identity‐unlinked technique from
G B, Green +5 more
openaire +2 more sources
Tissue-specific interactions of TNI isoforms with other TN subunits and tropomyosins in C. elegans: The role of the C- and N-terminal extensions [PDF]
The aim of this study is to investigate the function of the C-terminal extension of three troponin I isoforms, that are unique to the body wall muscles of Caenorhabditis elegans and to understand the molecular interactions within the TN complex between ...
al-Hillawi +35 more
core +1 more source
Clinical Utility of Cardiac Troponin I and Cardiac Troponin T Measurements
The measurement of CK-MB remains the test of choice for confirmation or exclusion of AMI and probably will remain the test of choice for routine diagnosis in the near future.
Michaela Adamcová +2 more
doaj +1 more source
Troponin T level in children with acute chest diseases and respiratory distress
Background Respiratory distress owing to pulmonary causes is the most common cause of visits to the pediatric emergency departments. Cardiac complications are reported to occur in acute respiratory tract diseases such as myocarditis, pericarditis, heart ...
Laila A.G Hegazy +3 more
doaj +1 more source
Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen +5 more
core +1 more source
Aims The aim of this study was to establish age‐specific and sex‐specific cut‐off values for N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) and high‐sensitivity troponin T (hs‐troponin T) in healthy subjects and assess cardiac biomarkers as ...
Maria Averina +3 more
doaj +1 more source
Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core +2 more sources
Background Metformin has favorable effects on cardiovascular outcomes in both newly onset and advanced type 2 diabetes, as previously reported findings from the UK Prospective Diabetes Study and the HOME trial have demonstrated.
Johanna M. G. Stultiens +7 more
doaj +1 more source
Prognostic value of troponins in acute coronary syndrome depends upon patient age [PDF]
Peer ...
Bachmann, M. O. +5 more
core +1 more source
The Solution Structure of a Cardiac Troponin C−Troponin I−Troponin T Complex Shows a Somewhat Compact Troponin C Interacting with an Extended Troponin I−Troponin T Component [PDF]
We have investigated the structure of the cTnC-cTnI-cTnT(198-298) calcium-saturated, ternary cardiac troponin complex by small-angle scattering with contrast variation. Shape restoration was also applied to the scattering information resulting from the deuterated cTnC subunit, the unlabeled cTnI-cTnT(198-298) subunits, and the entire complex.
William T, Heller +4 more
openaire +2 more sources

