Frontiers in Medicine, 2022 BackgroundChronic kidney disease has emerged as a significant independent risk factor for cardiovascular disease. Cardiovascular calcification is an active process involving a complex interaction of inducers and inhibitors.
Kamal M. Okasha +17 more
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Cardiac Troponin T and Troponin I in the General Population
Circulation, 2019 Supplemental Digital Content is available in the text.
P. Welsh +14 more
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Which diagnostic tests are most useful in a chest pain unit protocol? [PDF]
, 2005 Background The chest pain unit (CPU) provides rapid diagnostic assessment for patients with acute, undifferentiated chest pain, using a combination of electrocardiographic (ECG) recording, biochemical markers and provocative cardiac testing.
Angelini, K. +4 more
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Irish Journal of Medical Science, 2004 In recent years the use of troponin testing to monitor myocardial damage has become more pervasive and prominent, replacing the old style CK-MB measurement. Troponin elevation is a marker of cardiac injury and high risk, it is also raised in a minority of acute coronary syndrome patients. However, it is important for clinicians to realise that a single
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Location of troponin I‐binding on troponin T sequence [PDF]
FEBS Letters, 1982 Interaction between troponin T and troponin I is considered as one of those necessary for the calI cium-regulatory mechanism in the thin filament of vertebrate striated muscles [ 1,2]. Studies using chymotryptic subfragments of troponin T showed that the affinity for troponin I is localized in the region of the C-terminal 101 residues, termed troponin ...
Masaru Tanokura, Iwao Ohtsuki
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The Solution Structure of a Cardiac Troponin C−Troponin I−Troponin T Complex Shows a Somewhat Compact Troponin C Interacting with an Extended Troponin I−Troponin T Component [PDF]
Biochemistry, 2002 We have investigated the structure of the cTnC-cTnI-cTnT(198-298) calcium-saturated, ternary cardiac troponin complex by small-angle scattering with contrast variation. Shape restoration was also applied to the scattering information resulting from the deuterated cTnC subunit, the unlabeled cTnI-cTnT(198-298) subunits, and the entire complex.
Paul R. Rosevear +4 more
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Tissue-specific interactions of TNI isoforms with other TN subunits and tropomyosins in C. elegans: The role of the C- and N-terminal extensions [PDF]
, 2007 The aim of this study is to investigate the function of the C-terminal extension of three troponin I isoforms, that are unique to the body wall muscles of Caenorhabditis elegans and to understand the molecular interactions within the TN complex between ...
al-Hillawi +35 more
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To Assess Relationship of Lipoprotein (a) with Severity of Coronary Artery Disease in Patients with Acute Myocardial Infarction: A Hospital based Cross-sectional Study [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Elevated plasma concentrations of lipoprotein {Lp(a)} have been consistently shown to be a risk factor for the development of a spectrum of thrombotic and atherosclerotic disorders including Coronary Artery Disease (CAD). Aim: To assess
Gaurav Bhandari +2 more
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Disposable Printed Lateral Flow Electrochemical Immunosensors for Human Cardiac Troponin T [PDF]
IEEE Sensors Journal, 2018 Here we report an electrochemical ELISA approach for cardiac Troponin T (cTnT) determination based on a lateral flow membrane with underlying screen printed electrodes (\u3c;100 Ω /cm 2 ).
E. Dempsey, D. Rathod
semanticscholar +3 more sources
Myocardial injury in noncardiac surgery [PDF]
Korean Journal of Anesthesiology, 2022 Myocardial injury is defined as an elevation of cardiac troponin (cTn) levels with or without associated ischemic symptoms. Robust evidence suggests that myocardial injury increases postoperative mortality after noncardiac surgery.
Jungchan Park, Jong-Hwan Lee
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