Results 71 to 80 of about 12,042,484 (342)

Avaliação dos valores séricos de troponina I cardíaca em crianças menores de 1 ano de idade Evaluation of serum cardiac troponin I values in children less than 1 year of age

Brazilian Journal of Cardiovascular Surgery, 2008
OBJETIVO: Verificar os valores séricos para troponina I cardíaca em crianças abaixo de um ano de idade, sem disfunção cardíaca clínica. MÉTODOS: Os níveis séricos de troponina I cardíaca foram determinados em 99 crianças com idade abaixo de um ano ...
Antonio Carlos Arruda Souto, Werther Brunow de Carvalho   +1 more
doaj   +1 more source

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

Nanoparticulate Copper Cluster-Mediated Biosensing of Cardiac Biomolecular Markers

Biosensors
Being a leading cause of death, heart diseases across the globe need special attention to enable early diagnosis. Metal nanoparticle-mediated biosensors are useful clinical tools for the early detection of bio-analytes. The size-dependent surface plasmon
Lakshmi V. Nair, Jarred Wheeler, Yaelyn Ha, Kimberly M. Jones, Jesse Jones, Vinoy Thomas   +5 more
doaj   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source

Diagnostic Value of Troponin I and T to Predict Mortality in Patients Undergoing Hemodialysis

Archives of Anesthesia and Critical Care, 2018
Background: There is no known biomarker to predict the mortality risk in patients undergoing dialysis in the intensive care unit (ICU). Therefore, the current study aimed to determine the diagnostic value of troponin I and T in this respect.
Seyed Taghi Hashemi, Babak Alikiaii, Samira Ghasemi   +2 more
doaj  

Drug-Induced Rhabdomyolysis with Elevated Cardiac Troponin T

Case Reports in Medicine, 2015
The essential role of cardiac troponin in the diagnosis of acute myocardial infarction has led to the development of high-sensitivity assays, which are able to detect very small amounts of myocardial necrosis.
Gro Egholm, Manan Pareek
doaj   +1 more source

Prospective validation of a 1-hour algorithm to rule-out and rule-in acute myocardial infarction using a high-sensitivity cardiac troponin T assay

Canadian Medical Association Journal, 2015
Background: We aimed to prospectively validate a novel 1-hour algorithm using high-sensitivity cardiac troponin T measurement for early rule-out and rule-in of acute myocardial infarction (MI).
T. Reichlin, R. Twerenbold, K. Wildi, M. Gimenez, Nathalie Bergsma, P. Haaf, Sophie Druey, C. Puelacher, B. Moehring, M. Freese, C. Stelzig, Lian Krivoshei, P. Hillinger, C. Jäger, Thomas Herrmann, Philipp Kreutzinger, M. Radosavac, Zoraida Moreno Weidmann, K. Pershyna, Ursina Honegger, M. Wagener, Thierry Vuillomenet, I. Campodarve, R. Bingisser, Ò. Miró, K. Rentsch, S. Bassetti, S. Osswald, C. Mueller   +28 more
semanticscholar   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source

Cardiac troponin T quantitative assay failure as a result of antibody interference

African Journal of Laboratory Medicine, 2013
Background: Immunoassays are prone to interference by various substances which may cause inaccurate results. This type of interference is difficult to detect analytically.
Philip H. Fortgens, Fierdoz Omar
doaj   +1 more source

Measurement of Troponin in Cardiomyopathies [PDF]

Cardiogenetics, 2016
Troponins are thin myofilament proteins that regulate the contraction of cardiac and skeletal muscle. The cardio-specific troponin I (TnI) and T (TnT) proteins are sensitive and specific biomarkers of myocardial injury which over the past twenty years have revolutionised the diagnosis and management of myocardial infarction.
Connelly, Andrew, Findlay, Iain N., Coats, Caroline J.   +2 more
openaire   +3 more sources