Results 71 to 80 of about 12,042,484 (342)
OBJETIVO: Verificar os valores séricos para troponina I cardíaca em crianças abaixo de um ano de idade, sem disfunção cardíaca clínica. MÉTODOS: Os níveis séricos de troponina I cardíaca foram determinados em 99 crianças com idade abaixo de um ano ...
Antonio Carlos Arruda Souto+1 more
doaj +1 more source
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang+12 more
wiley +1 more source
Nanoparticulate Copper Cluster-Mediated Biosensing of Cardiac Biomolecular Markers
Being a leading cause of death, heart diseases across the globe need special attention to enable early diagnosis. Metal nanoparticle-mediated biosensors are useful clinical tools for the early detection of bio-analytes. The size-dependent surface plasmon
Lakshmi V. Nair+5 more
doaj +1 more source
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li+5 more
wiley +1 more source
Diagnostic Value of Troponin I and T to Predict Mortality in Patients Undergoing Hemodialysis
Background: There is no known biomarker to predict the mortality risk in patients undergoing dialysis in the intensive care unit (ICU). Therefore, the current study aimed to determine the diagnostic value of troponin I and T in this respect.
Seyed Taghi Hashemi+2 more
doaj
Drug-Induced Rhabdomyolysis with Elevated Cardiac Troponin T
The essential role of cardiac troponin in the diagnosis of acute myocardial infarction has led to the development of high-sensitivity assays, which are able to detect very small amounts of myocardial necrosis.
Gro Egholm, Manan Pareek
doaj +1 more source
Background: We aimed to prospectively validate a novel 1-hour algorithm using high-sensitivity cardiac troponin T measurement for early rule-out and rule-in of acute myocardial infarction (MI).
T. Reichlin+28 more
semanticscholar +1 more source
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng+9 more
wiley +1 more source
Cardiac troponin T quantitative assay failure as a result of antibody interference
Background: Immunoassays are prone to interference by various substances which may cause inaccurate results. This type of interference is difficult to detect analytically.
Philip H. Fortgens, Fierdoz Omar
doaj +1 more source
Measurement of Troponin in Cardiomyopathies [PDF]
Troponins are thin myofilament proteins that regulate the contraction of cardiac and skeletal muscle. The cardio-specific troponin I (TnI) and T (TnT) proteins are sensitive and specific biomarkers of myocardial injury which over the past twenty years have revolutionised the diagnosis and management of myocardial infarction.
Connelly, Andrew+2 more
openaire +3 more sources