Results 81 to 90 of about 167,379 (349)

Cardiac troponin T as a serum biomarker of respiratory impairment in amyotrophic lateral sclerosis

open access: yesAnnals of Clinical and Translational Neurology
Objective Informative biomarkers are an urgent need in the management of amyotrophic lateral sclerosis. Serum cardiac troponin T is elevated in the majority of amyotrophic lateral sclerosis patients and increases with disease progression.
Teresa Koch   +8 more
doaj   +1 more source

Biochemical Markers of Cardiotoxicity of High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation in Patients with Malignant Lymphoproliferative Disorders

open access: yesКлиническая онкогематология, 2016
Background. High-dose chemotherapy (HDCT) with autologous hematopoietic stem cells transplantation (auto-HSCT) is an effective therapeutic option for patients with Hodgkin’s lymphoma and aggressive non-Hodgkin’s lymphomas in those cases, when the ...
Vladislav Olegovich Sarzhevskii   +2 more
doaj   +1 more source

Influence of case definition on incidence and outcome of acute coronary syndromes [PDF]

open access: yes, 2016
© 2016, BMJ Publishing Group. All rights reserved. Objective: Acute coronary syndromes (ACS) are common, but their incidence and outcome might depend greatly on how data are collected.
Alamgir, Farqad   +11 more
core   +2 more sources

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

open access: yesAdvanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang   +7 more
wiley   +1 more source

Diagnostic Value of Troponin I and T to Predict Mortality in Patients Undergoing Hemodialysis

open access: yesArchives of Anesthesia and Critical Care, 2018
Background: There is no known biomarker to predict the mortality risk in patients undergoing dialysis in the intensive care unit (ICU). Therefore, the current study aimed to determine the diagnostic value of troponin I and T in this respect.
Seyed Taghi Hashemi   +2 more
doaj  

Cardiac troponin T quantitative assay failure as a result of antibody interference

open access: yesAfrican Journal of Laboratory Medicine, 2013
Background: Immunoassays are prone to interference by various substances which may cause inaccurate results. This type of interference is difficult to detect analytically.
Philip H. Fortgens, Fierdoz Omar
doaj   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

open access: yesAdvanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen   +10 more
wiley   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng   +15 more
wiley   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

open access: yesAdvanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao   +12 more
wiley   +1 more source

Diagnostic Values of Troponin I and T for Prediction of Mortality in Patients Hospitalized in Intensive care Unit and Need Hemodialysis in Alzahra Hospital, Isfahan, Iran, during 2015-16

open access: yesمجله دانشکده پزشکی اصفهان, 2017
Background: Some of previous studies showed that risk of mortality in patients who need hemodialysis and hospitalized in intensive care unit is higher but and biomarker is not detected for prediction of mortality in these patients.
Babak Alikiaii   +4 more
doaj  

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