Results 81 to 90 of about 161,005 (352)

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Proximity mapping of troponin T and troponin I in cardiac troponin using molecular dynamics simulations [PDF]

Biophysical Journal, 2009
The intersite distances from cTnT residues 240, 276, and 288 to cTnI N-terminal residues 5, 17, 27, 40, and to the cTnI C-terminal residues 131, 145, 152, 160, and 167 in reconstituted cTn were determined in the presence of Mg2+ and Mg2+ plus Ca2+ using FRET.
Wen-Ji Dong, Herbert C. Cheung, John M. Robinson, Jun Xing, Jayant James Jayasundar   +4 more
openaire   +2 more sources

Influence of case definition on incidence and outcome of acute coronary syndromes [PDF]

, 2016
© 2016, BMJ Publishing Group. All rights reserved. Objective: Acute coronary syndromes (ACS) are common, but their incidence and outcome might depend greatly on how data are collected.
Alamgir, Farqad, Atkin, Paul, Clark, Andrew L, Cleland, John G F, Goode, Kevin, Hoye, Angela, Kilpatrick, Eric, Panahi, Hossein, Rigby, Alan, Sherwi, Nasser, Thackray, Simon, Torabi, Azam   +11 more
core   +2 more sources

Vascularized and Perfusable Human Heart‐on‐a‐Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery

Advanced Materials, EarlyView.
This novel 3D human ischemic heart‐on‐a‐chip, with perfusable vasculature directly interfaced with myocardial tissue, replicates key aspects of ischemic heart injury. It also demonstrates the targeted delivery and therapeutic efficacy of cardiac homing peptide‐conjugated liposomes, validating the platform for drug and nanomedicine screening in ...
Junyoung Kim, Xuening Zhang, Richard Wang, Adrian Najer, Qiao You Lau, Ana Cammack‐Najera, Jang Ah Kim, Yoo Kyung Kang, Ruoxiao Xie, Hyemin Kim, Kai Xie, Hyeonji Lim, Tae‐Eun Park, Jinmyoung Joo, Molly M. Stevens   +14 more
wiley   +1 more source

High-sensitivity cardiac troponin T and copeptin assays to improve diagnostic accuracy of exercise stress test in patients with suspected coronary artery disease [PDF]

, 2014
Background: The average diagnostic sensitivity of exercise stress tests (ESTs) is lower than that of other non-invasive cardiac stress tests. The aim of the study was to examine whether high-sensitivity cardiac troponin T (hs-cTnT) or copeptin ...
Dörr, Oliver, Gaede, Luise, Hamm, Christian W., Hoffmann, Jedrzej, Liebetrau, Christoph, Möllmann, Helge, Nef, Holger M., Rolf, Andreas, Weber, Michael, Wolter, Jan S.   +9 more
core   +1 more source

Engineered Plasmonic and Fluorescent Nanomaterials for Biosensing, Motion, Imaging, and Therapeutic Applications

Advanced Materials, EarlyView.
A schematic illustration of how noble metals can be used to create nanoparticles (NPs) or nanoclusters (NCs). Noble metal NPs, due to their plasmonic properties, enable photothermal therapy and surface‐enhanced Raman scattering (SERS). In contrast, NCs, which lack a plasmonic resonance band, exhibit fluorescence, making them ideal for bioimaging ...
David Esporrín‐Ubieto, Juan C. Fraire, Daniel Sánchez‐deAlcázar, Samuel Sánchez   +3 more
wiley   +1 more source

Increased plasma levels of NT-proBNP, Troponin T and GDF-15 are driven by persistent AF and associated comorbidities: Data from the AF-RISK study

International Journal of Cardiology: Heart & Vasculature, 2022
Atrial fibrillation (AF) is a progressive disease, and early recognition and management may reflect an important strategy to reduce its disease burden.
L.M.G. Meems, V. Artola Arita, M. Velt, E.A.M.P. Dudink, H.J.G.M. Crijns, I.C. Van Gelder, M. Rienstra   +6 more
doaj   +1 more source

ST2 and Multimarker Testing in Acute Decompensated Heart Failure [PDF]

, 2015
Most data on heart failure biomarkers have been derived from patient cohorts with chronic disease. However, risk prediction in patients admitted with acute decompensated heart failure (ADHF) remains a challenge.
Antoni, Md, Bayes, Genis, DI SOMMA, Salvatore, Maisel, Alan S., Md,, Md,, Md,, Mebazaa, Alexandre   +7 more
core   +1 more source

Volumetric 3D Printing and Melt‐Electrowriting to Fabricate Implantable Reinforced Cardiac Tissue Patches

Advanced Materials, EarlyView.
This study presents an implantable reinforced cardiac patch (RCPatch) combining volumetrically 3D‐printed metamaterials with melt‐electrowritten (MEW) meshes. The design integrates tunable stiff polymer structures with soft, cell‐laden hydrogels. The RCPatch withstands suturing, intraventricular pressure, and cardiac contraction in a large animal ...
Lewis S. Jones, Hector Rodriguez Cetina Biefer, Manuel Mekkattu, Quinten Thijssen, Alessio Amicone, Anna Bock, Miriam Weisskopf, Dennis Zorndt, Debora Meier, Li Zheng, Melanie Generali, Robert K. Katzschmann, Omer Dzemali   +12 more
wiley   +1 more source

Evaluation of the Relationship between Troponin T Level and Prognosis of Preterm Neonates Admitted to Neonatal Intensive Care Unit of Fatemieh Hospital in Hamadan

پزشکی بالینی ابن سینا, 2022
Background and Objective: Due to the prevalence of myocardial dysfunction and Patent Ductus Arteriosus (PDA) in a large number of preterm neonates, the prognosis of these infants is highly related to their early diagnosis and treatment.
Asadolah Tanasan, Mohammad Kazem Sabzehei, Pegah Ameri, Ali Amri, Fatemeh Yaghoubi, Hossein Ariana   +5 more
doaj