Results 81 to 90 of about 13,150 (209)

Efficacy of In‐Office Bleaching Using 35% Hydrogen Peroxide in an Attachable Syringe Varying the Application Tip: A Double‐Blind Randomized Clinical Trial

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective This randomized clinical trial evaluated the bleaching efficacy (BE), absolute risk and intensity of tooth sensitivity (TS), gingival irritation (GI), and esthetic self‐perception (ES) of an in‐office bleaching gel with an attachable syringe using different application tips in a randomized, double‐blind (participant‐ and evaluator ...
Gabrielle Gomes Centenaro   +4 more
wiley   +1 more source

TRPA1: irritant detector of the airways

open access: yesThe Journal of Physiology, 2008
The respiratory tract is innervated by primary afferent sensory neurons that respond to mechanical and chemical stimuli (Taylor-Clark & Undem, 2006). The majority of these neurons are unmyelinated C-fibres that respond to noxious chemicals, such as reactive oxygen species (ROS), the main irritants of tear gas, air pollution and burning vegetation ...
K A, Gerhold, D M, Bautista
openaire   +3 more sources

Effects of Clenching Intensity and Duration on Pressure Pain Threshold and Masseter‐Muscle Stiffness Under Standardised EMG‐Based Contraction Exposure

open access: yesJournal of Oral Rehabilitation, EarlyView.
Under equivalent prescribed EMG‐based contraction exposure, pressure pain threshold was modestly but significantly lower immediately after low‐intensity, long‐duration clenching than after high‐intensity, short‐duration clenching, whereas the latter induced a transient reduction in masseter‐muscle stiffness.
Keisuke Miyazono   +3 more
wiley   +1 more source

PILOT STUDY OF THE ASSOCIATION OF TRPA1 AND TRPV1 GENE POLYMORPHISMS WITH MYOCARDIAL INFARCTION

open access: yesАтеросклероз, 2019
The aim of the study was to investigate the association of SNPs in the TRPA1 (rs13268757) and TRPV1 (rs222747) genes with myocardial infarction. Material and methods.
P. S. Orlov   +5 more
doaj   +1 more source

Effects of Pistacia lentiscus Leaf‐Twig and Resin (Mastic) Oils on Salivary Flow in Healthy Individuals

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Pistacia lentiscus L. tree is known for its aromatic mastic gum containing terpenes α‐pinene and β‐myrcene, and has been applied as a traditional remedy in oral care for centuries. Previously, intranasal exposure to mastic resin volatiles increased salivary flow in healthy and dry‐mouth individuals. This study assessed the biological
Wiktoria Potocka   +4 more
wiley   +1 more source

Modulation of TRPA1 channel activity by Cdk5 in sensory neurons

open access: yesChannels, 2018
Transient receptor potential cation channel, subfamily A, member 1 (TRPA1), is activated by a broad range of noxious stimuli. Cdk5, a member of the Cdk family, has recently been identified as a modulator of pain signaling pathways.
Michael A. Sulak   +4 more
doaj   +1 more source

The cold‐water immersion recovery–adaptation paradox: Reconciling acute parasympathetic and analgesic benefits with chronic hypertrophy attenuation

open access: yesExperimental Physiology, EarlyView.
Abstract Cold‐water immersion (CWI) is among the most widely used post‐exercise recovery modalities in elite sport and clinical rehabilitation, yet a fundamental paradox now emerges from the evidence: the same protocols that accelerate parasympathetic reactivation and reduce perceived muscle soreness also suppress the molecular and cellular machinery ...
Jose Francisco Tornero‐Aguilera   +8 more
wiley   +1 more source

Camphor Attenuates Hyperalgesia in Neuropathic Pain Models in Mice

open access: yesJournal of Pain Research, 2023
Ziyuan Li,1,* Yu Gan,1,* Ting Kang,1,* Yi Zhao,1 Tianguang Huang,2 Yuhao Chen,3 Jin Liu,1 Bowen Ke1 1Department of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of ...
Li Z   +7 more
doaj  

Investigation of Cuprizone-Induced Demyelination in mGFAP-Driven Conditional Transient Receptor Potential Ankyrin 1 (TRPA1) Receptor Knockout Mice

open access: yesCells, 2019
Transient receptor potential ankyrin 1 (TRPA1) receptors are non-selective cation channels responsive to a variety of exogenous irritants and endogenous stimuli including products of oxidative stress.
Gábor Kriszta   +7 more
doaj   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

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