Results 211 to 220 of about 18,800 (265)

Potential of cocoa (Theobroma cacao) shell for diabetic neuropathy targeting transient receptor potential canonical (TRPC): an in silico study

Maryo Adjie Pangestu, Sarmoko Sarmoko, I Gede Raditya Purwanata, Titah Zusela   +3 more
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Cholesterol inhibits capsaicin activation of the TRPV1 channel. [PDF]

Channels (Austin)
Brandwine-Shemmer T, Barbera NA, Levitan I, Minke B.   +3 more
europepmc   +1 more source

TRPC channels mediate cardiac hypertrophy

TRPC channels mediate cardiac hypertrophy
openaire  

TRPC channels in sensory systems

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The mammalian TRPC cation channels

Biochimica Et Biophysica Acta - Molecular Cell Research, 2004
Transient Receptor Potential-Canonical (TRPC) channels are mammalian homologs of Transient Receptor Potential (TRP), a Ca(2+)-permeable channel involved in the phospholipase C-regulated photoreceptor activation mechanism in Drosophila. The seven mammalian TRPCs constitute a family of channels which have been proposed to function as store-operated as ...
Guillermo Vazquez, Mohamed Trebak, James W Putney   +2 more
exaly   +3 more sources

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TRPC Channels: Interacting Proteins

2007
TRP channels, in particular the TRPC and TRPV subfamilies, have emerged as important constituents of the receptor-activated Ca2+ influx mechanism triggered by hormones, growth factors, and neurotransmitters through activation ofphospholipase C (PLC).
K, Kiselyov, D M, Shin, J Y, Kim, J P, Yuan, S, Muallem   +4 more
openaire   +2 more sources

TRPC channels as signal transducers

Pflügers Archiv - European Journal of Physiology, 2005
The study of the TRPC cation channels as signal transducers in sensory neurons is in its infancy. Mechanoreceptors that monitor arterial pressure are prime candidates for the involvement of TRPC channels as either primary mechanical transducers or as modulators of the transduction process. Their activity patterns can be regulated by growth factors such
Patricia A, Glazebrook, William P, Schilling, Diana L, Kunze   +2 more
openaire   +2 more sources

TRPCs as MS Channels

2007
This chapter reviews recent evidence indicating that canonical or classical transient receptor potential (TRPC) channels are directly or indirectly mechanosensitive (MS) and can therefore be designated as mechano-operated channels (MOCs). The MS functions of TRPCs may be mechanistically related to their better known functions as store-operated and ...
Owen P, Hamill, Rosario, Maroto
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RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC

Cell Calcium, 2008
TRPCs function as cation channels in non-excitable cells. The N-terminal tails of all TRPCs contain an ankyrin-like repeat domain, one of the most common protein-protein interaction motifs. Using a yeast two-hybrid screening approach, we found that RNF24, a new membrane RING-H2 protein, interacted with the ankyrin-like repeat domain of TRPC6.
Marc P, Lussier, Pascale K, Lepage, Simon M, Bousquet, Guylain, Boulay   +3 more
openaire   +2 more sources

TRPC Channels and Glioma

2017
Glioma is the most common type of brain tumors and malignant glioma is extremely lethal, with patients' 5-year survival rate less than 10%. Treatment of gliomas poses remarkable clinical challenges, not only because of their particular localization but also because glioma cells possess several malignant biological features, including highly ...
Shanshan, Li, Xia, Ding
openaire   +2 more sources