Results 81 to 90 of about 6,014 (173)

Regulation of TRPC6 channel by hydrogen peroxide

The FASEB Journal, 2009
The present study was performed to examine the effect of H 2 O 2 on TRPC6 channel in HEK293t cells. In the TRPC6 expressing cells, H 2 O
Sarabeth Marie Graham, Min Ding, Sherry Sours‐Brothers, Rong Ma   +3 more
openaire   +1 more source

Distribution of TRPC1, TRPC3, and TRPC6 in the human thyroid

Pathology - Research and Practice
Little is known about the protein expression of the transient receptor potential canonical (TRPC) channels 1, 3, and 6 in the thyroid. Research in human tissue is insufficient. Our aim was to investigate the distribution of TRPC1, 3, and 6 in the healthy human thyroid.Healthy samples were collected from seven nitrite pickling salt-ethanol-polyethylene ...
Kirstein, Emilie, Diebolt, Coline M., Wagner, Mathias, Bozzato, Alessandro, Federspiel, Jan M., Schaudien, Dirk, Tschernig, Thomas, Englisch, Colya N.   +7 more
openaire   +2 more sources

TRPC6-mediated calcium signaling is involved in T2DM-induced hepatic steatosis and fibrosis and the modulation of ginsenoside Rg1

Journal of Pharmacological Sciences
Hepatic steatosis and fibrosis represent major complications of type 2 diabetes mellitus (T2DM) with limited therapeutic options. Ginsenoside Rg1, a bioactive constituent of Panax ginseng, exhibits hepatoprotective properties, but its mechanism in ...
Haoyu Liang, Yulu Qian, Fujie Diao, Jinyao Bo, Lei Fan, Xing Zhu, Tanzhen Xu, Weizu Li   +7 more
doaj   +1 more source

Delivery of siRNAs Against Selective Ion Channels and Transporter Genes Using Hyaluronic Acid-coupled Carbonate Apatite Nanoparticles Synergistically Inhibits Growth and Survival of Breast Cancer Cells

International Journal of Nanomedicine
Mohammad Borhan Uddin,1 Mark M Banaszak Holl,2,3 Ezharul Hoque Chowdhury4,5 1Department of Pharmaceutical Sciences, School of Health and Life Sciences, North South University, Dhaka, Bangladesh; 2Department of Mechanical and Materials Engineering, School
Uddin MB, Holl MMB, Chowdhury EH
doaj  

TRPC6 is a Biomarker for Prognosis and Immunotherapy of Stomach Adenocarcinoma Based on Bioinformatic Analysis and Experimental Validation

ImmunoTargets and Therapy
Xingchi Hu,1,2 Hongwei Wang,1,2 Haitao Sun,3 Jingxin Zhang,3 ZhenXiong Ye,4 Zhenhua Huang3 1Department of General Surgery, Yancheng First Hospital, Affiliated Hospital of Nanjing University Medical School, Yancheng, Jiangsu, 224000, People’s Republic of ...
Hu X, Wang H, Sun H, Zhang J, Ye Z, Huang Z   +5 more
doaj  

Functional evaluation of TRPC6 missense variants in cancer patients via molecular docking analysis compared with patch Clamp electrophysiology. [PDF]

J Biol Chem
Wu Y, Sun X, Reddy JS, Advani PP, Boddicker NJ, Cerhan JR, Villarraga HR, Asirvatham SJ, Wang RX, Lee HC, Norton N, Zanchi FB, Lu T.   +12 more
europepmc   +1 more source

Transient receptor potential canonical (TRPC) channels in diabetes and associated complications. [PDF]

Channels (Austin)
Wu Y, Chen S, Xia X.
europepmc   +1 more source

An Inducible hiPSC-Derived Human Podocyte Model for Functional Analysis of TRPC6 Variants Associated with FSGS. [PDF]

Cells
Batool L, Hariharan K, Stölting G, Zhong T, Tsvetkov D, Gossen M, Kurtz A.   +6 more
europepmc   +1 more source

uPAR/suPAR Signaling and Organ Crosstalk in Cardiovascular-Kidney-Metabolic Syndrome. [PDF]

Circ Res
Hayek SS, Dryer SE.
europepmc   +1 more source

Phenotypic Subacute Toxicity Assessment of Intranasally Administered Larixyl Acetate: Implications for Potential Airway Applications. [PDF]

J Xenobiot
Kalaji Z, Hachim I, Almazrouei M, Habbal H, Mohan VB, Mohammad MG, Hamoudi R, Halwani R.   +7 more
europepmc   +1 more source