Results 31 to 40 of about 41,565 (180)

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Voltage-gated ion channels [PDF]

, 2017
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
,, Alexander, Stephen Ph, Davies, Jamie A, Faccenda, Elena, Harding, Simon D, Kelly, Eamonn, Marrion, Neil V, Pawson, Adam J, Peters, John A, Sharman, Joanna L, Southan, Christopher, Striessnig, Jörg   +11 more
core   +5 more sources

Expression and function of transient receptor potential channels in the female bovine reproductive tract [PDF]

, 2016
© 2016 Elsevier Inc. The epithelium lining the oviduct is critical for early reproductive events, many of which are mediated via intracellular calcium ions.
Atkin, Stephen L., Ghavideldarestani, Maryam, Leese, Henry J., Sturmey, Roger G.   +3 more
core   +2 more sources

Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons. [PDF]

, 2015
An increasing number of studies show that the activation of the innate immune system and inflammatory mechanisms play an important role in the pathogenesis of numerous diseases.
A Becerra, A Diogenes, A Halle, A Mathew, A Ozturk, A Riccio, A Salminen, A Tozzi, AD Fryer, AL Blasius, AM Binshtok, AS Sabnis, B Nilius, B Nilius, B Vandanmagsar, BA Miller, C Amantini, C Hoffmeister, C Inohara, C Schorn, CB Lessard, CC Ferraz, CK Park, Claudio Cardinali, CM Hecquet, Consuelo Amantini, D Wang, DA Andersson, DA Cockayne, DE Clapham, DG Perregaux, DJ Taxman, E Fonfria, E Lago de, E Park, EK Hoffmann, F Cevikbas, F Lang, F Thilo, G Santoni, G Trevisan, Giorgio Santoni, H Abdullah, H Karatas, H Kim, H Knowles, H Min, H Sakurai, HJ Ramos, IM Chiu, J Brown, J Minkiewicz, J Qi, J Reiser, J Zheng, JA Kummer, JC Ansel, JG Walsh, JM Cyphert, JP Rivero Vaccari de, JP White, JPY Ting, K Inoue, K Muraki, K Nakahira, K Rajamäki, K Schorder, K Shimada, K Yamashiro, L Cruz-Orengo, L Tsiokas, LA Carneiro, M Fukata, M Lamkanfi, M Papatriantafyllou, M Stoffels, M Tauseef, M Trevisani, Maria Morelli, Massimo Nabissi, Matteo Santoni, MB Morelli, MC Hermosura, MT Sorbara, N Fukuno, N Lendman, N Onohara, NL Weilinger, O Gross, O Takeuchi, P Holzer, P Wang, PJ Newman, R Madrid, R Penner, R Vennekens, R Zhou, S Alboni, S Caprodossi, S Chung, S Grundmann, S Kim, S Lakshmi, S Mariathasan, S Yamamoto, S Yamamoto, SL Cassel, SM Allan, SN Wu, SP Wilson, SR Jacobs, T Kawai, T Liu, T Murakami, T Numata, T Strowig, T Togo, TA Samad, TE Woudenberg-Vrenken, TK Lapointe, TM Link, TZ Veres, V Chubanov, V Compan, V Pétrilli, V Souslova, W Ding, W Liedtke, WW Li, XC Zhang, Y Takada, YN Gong, Z Zhang, Z Zhong   +133 more
core   +3 more sources

Divide and Conquer: High Resolution Structural Information on TRP Channel Fragments [PDF]

, 2009
Understanding how proteins facilitate signaling and substrate transport across biological membranes is an important frontier of structural biology. Membrane proteins are the doors and windows of cells: many membrane proteins are gates of entry into or ...
Bandell, Chubanov, Frey, Fujiwara, Gaudet, Gaudet, Gaudet, Grigoryan, Hinman, Jasti, Jin, Jordt, Lepage, Lishko, Long, Macpherson, McCleverty, Minor, Montell, Moore, Nadler, Perraud, Phelps, Phelps, Rachelle Gaudet, Ramsey, Runnels, Salazar, Schaefer, Schindl, Schlingmann, Tsuruda, Venkatachalam, Wetlaufer, Yamaguchi   +34 more
core   +2 more sources

TRPV2 Channels Contribute to Stretch-Activated Cation Currents and Myogenic Constriction in Retinal Arterioles [PDF]

, 2016
Purpose: Activation of the transient receptor potential channels, TRPC6, TRPM4, and TRPP1 (PKD2), has been shown to contribute to the myogenic constriction of cerebral arteries.
Curtis, Tim M., Dash, Durga P, Fernández, José A, McGahon, Mary K, McGeown, J. Graham, McKee, Jon, Simpson, David A, Zholos, Alex V   +7 more
core   +1 more source

Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins [PDF]

, 2018
Cold-inducible RNA-binding protein (CIRP), RNA-binding motif protein 3 (RBM3) and serine and arginine rich splicing factor 5 (SRSF5) are RNA-binding proteins that are transcriptionally upregulated in response to moderately low temperatures and a variety ...
Fujita Jun, Fujita Takanori, Higashitsuji Hiroaki, Itoh Katsuhiko, Liu Yu, Nishiyama Hiroyuki, Shibasaki Koji, 西山 博之   +7 more
core   +2 more sources

Analysis of dynamic spectrum leasing for coded Bi-directional communication [PDF]

, 2012
In this paper, we aim to present a cooperative relaying based two way wireless communication scheme which can provide both spectral and energy efficiency in future wireless networks.
Elmirghani, JMH, Hafeez, M
core   +1 more source

The Role of Neuro‐Immune Regulation in the Pathogenesis of Psoriasis

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Psoriasis is a chronic inflammatory skin disease characterized by abnormal proliferation of epidermal cells induced by an overactive immune system. In addition to the interaction between immune cells and keratinocytes, emerging research highlights the indispensable role of peripheral sensory neurons in the initiation and progression of psoriatic ...
Xin Liu, Mingyu Yu, Pan Zou, Suwen Liu, Jian Jiang, Liyang Ge, Su Jiang, Jingyu Zhang, Xin Wang, Hongxiang Chen, Poorani Gurumallesh Prabu   +10 more
wiley   +1 more source

The transient receptor potential family of ion channels

Genome Biology, 2011
SummaryThe transient receptor potential (TRP) multigene superfamily encodes integral membrane proteins that function as ion channels. Members of this family are conserved in yeast, invertebrates and vertebrates.
B. Nilius, G. Owsianik
semanticscholar   +1 more source

Thermosensory TRPV Heterotetramers Drive Seasonal Polyphenism: Molecular Basis of CcIav/CcNan‐PKCα‐AKH/AKHR Signaling in Pear Psyllid Morph Transition

Advanced Science, Volume 12, Issue 45, December 4, 2025.
At 2 5 °C, thermal activation initiates: i) CcIav/CcNan heterotetramer assembly → Ca2⁺ influx; ii) CcPKCα phosphorylation → AKH signaling potentiation; iii) CcAKH1 binding to membrane‐localized CcAKHR → energy mobilization (lipid catabolism/glycogenolysis) and vitellogenin transport via follicular patency; iv) Oocyte maturation → summer‐form nymph ...
Jianying Li, Zhixian Zhang, Yilin Wang, Yue Yang, Jiarui Wang, Xueyi Ruan, Songdou Zhang   +6 more
wiley   +1 more source