Results 111 to 120 of about 10,867 (203)

Transient Receptor Potential Cation Channel Subfamily Vanilloid 4 and 3 in the Inner Ear Protect Hearing in Mice

Frontiers in Molecular Neuroscience, 2019
The transient receptor potential cation channel, vanilloid type (TRPV) 3, is a member of the TRPV subfamily that is expressed predominantly in the skin, hair follicles, and gastrointestinal tract. It is also distributed in the organ of Corti of the inner
Shengnan Wang, Shengnan Wang, Shengnan Wang, Shengnan Wang, Qiaowei Geng, Qiaowei Geng, Qiaowei Geng, Qiaowei Geng, Lifang Huo, Lifang Huo, Lifang Huo, Yirui Ma, Yirui Ma, Yirui Ma, Yirui Ma, Yiting Gao, Yiting Gao, Yiting Gao, Yiting Gao, Wei Zhang, Wei Zhang, Wei Zhang, Hailin Zhang, Hailin Zhang, Hailin Zhang, Hailin Zhang, Ping Lv, Ping Lv, Ping Lv, Ping Lv, Zhanfeng Jia, Zhanfeng Jia, Zhanfeng Jia, Zhanfeng Jia   +33 more
doaj   +1 more source

Effect of Moxibustion of “Dachangshu”(BL 25) Area on Pain Reaction and TRPV 1 mRNA Expression of Bone Marrow Cells in Visceral Hyperalgesia Rats

针刺研究, 2013
Objective To observe the effect of moxibustion of "Dachangshu"(BL 25) on pain reaction and expression of transient receptor potential vanilloid 1(TRPV 1) of bone marrow cells in visceral hyperalgesia(VHA) rats so as to explore its mechanism underlying ...
FU Cui-ping1, 2, LIU Ai-ling1, 2, YANG Xing-xia1, 2, ZOU Wei-ying1, YANG Bei1, ZHANG Da-lei1, CHEN Ting1   +9 more
doaj   +2 more sources

Co-administration of cannabidiol and capsazepine reduces L-DOPA-induced dyskinesia in mice: Possible mechanism of action

Neurobiology of Disease, 2016
Pharmacological manipulation of the endocannabinoid system represents a promising therapy to alleviate L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia (LID) in Parkinson's disease (PD).
Maurício dos-Santos-Pereira, Célia Aparecida da-Silva, Francisco Silveira Guimarães, Elaine Del-Bel   +3 more
doaj   +1 more source

Structural Insights into TRPV Channel Gating

The FASEB Journal, 2020
The transient receptor potential vanilloid 5 (TRPV5) channel is a highly calcium selective ion channel that regulates systemic calcium homeostasis by acting as a critical gate for calcium reabsorption in the kidney. Human polymorphisms of this channel have exemplified the importance of TRPV5 in disorders of calcium homeostasis, but atomic level ...
openaire   +1 more source

TRPV Channel Structures in Health and Disease

The FASEB Journal, 2015
My lab is broadly interested in the mechanisms of signaling and transport across cellular membranes. Much of our research centers on TRP channels and their role in sensory perception. We focus on temperature‐sensitive ion channels, particularly TRPV1, TRPV4 and TRPA1.
openaire   +1 more source

Effect of Manual Acupuncture,Electroacupuncture and Moxibustion on Intestinal Motility and Expression of Enteric Nervous Activity Related Proteins in Functional Constipation Rats

针刺研究, 2017
Objective To compare the effect of manual acupuncture(MA),electroacupuncture(EA)and moxibustion interventions on intestinal motility and expression of enteric nervous activity related proteins calcitonin gene related peptide(CGRP),transient receptor ...
ZHANG Xin, ZHANG Xuan-ping, DU Yu-zhu, XING Hai-jiao, JIA Rui, PAN Li-jia, XU Jing, JIA Chun-sheng   +7 more
doaj   +2 more sources

Expresión del receptor de potencial transitorio tipo 1 (TRPV-1) en placenta humana normal y preeclámptica [PDF]

, 2016
La preeclampsia (PE) es un síndrome multisistémico caracterizado por una anormal placentación. Aunque su etiología se desconoce, existen numerosos trabajos que demuestran que esta patología se asocia con la reducción o el anormal funcionamiento de una ...
Leguizamon, G., Moya, G., Martínez, N., Maskin, B., Abán, C., Farina, M., Damiano, A.   +6 more
core  

Lymphocyte TRPV 1-4 Gene Expression and MIF Blood Levels in a Young Girl Clinically Diagnosed With HSAN IV

, 2011
OBJECTIVE: Patients with congenital insensitivity to pain are unable to sense pain and temperature. They undergo many injuries, inflammatory state, and infections.
Bergamaschi R., Lima M., BERGAMASCHI, ROSALBA, Spinsanti G, Spinsanti G., Bachiocco V, Romagnoli R, Aloisi AM, Aloisi A. M., Bachiocco V., Romagnoli R., Sorda G, LIMA, MARIO, Sorda G.   +13 more
core   +1 more source

Multiple TRPV-Expressing Neurons Contribute to Hyperoxia Avoidance

, 2013
(A) Aerotaxis of TRPV single mutants. The median preferred oxygen concentration of ocr-2 mutants was significantly higher than N2 (p
Cornelia I Bargmann (1139), Nikolas Chronis (274685), David S Karow (274687), Michael A Marletta (274689), Andy J Chang (274683)   +4 more
core   +1 more source

Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPV Ion Channels

, 2013
Transient receptor potential (TRP) proteins are cation channels composed of a transmembrane domain flanked by large N- and C-terminal cytoplasmic domains.
Huang, Robert J., Wang, Ruiqi Rachel, Phelps, Christopher B., Gaudet, Rachelle, Lishko, Polina V.   +4 more
core   +1 more source