Results 71 to 80 of about 10,867 (203)
, 2022 The transient receptor potential vanilloid (TRPV) ion channel family is involved in multiple sensory and physiological functions including thermosensing and temperature-dependent neuroendocrine regulation.
Christina A. Bergqvist (5398214) +4 more
core +1 more source
The Journal of Dermatology, EarlyView.ABSTRACT Hard‐to‐heal wounds, such as diabetic foot ulcers and pressure injuries, pose major clinical challenges due to chronic inflammation and cellular senescence. Cellular senescence‐associated mechanisms, including stress‐responsive p53/p21 signaling and senescence‐associated secretory phenotype‐related inflammation, contribute to impaired wound ...
Daijiro Haba +6 more
wiley +1 more source
Role of the endovanilloid receptor TRPV-1 in intestinal inflammation and carcinogenesis [PDF]
, 2011 A link between inflammation and cancer has been clearly demonstrated and underlying chronic inflammation may be of particular relevance to gastrointestinal (GI) carcinogenesis, especially in colitis-associated cancer (CAC).
García de Vinuesa Antuñano, Amaya
core +1 more source
PLoS ONE, 2019 In response to noxious stimuli, planarians cease their typical ciliary gliding and exhibit an oscillatory type of locomotion called scrunching. We have previously characterized the biomechanics of scrunching and shown that it is induced by specific ...
Ziad Sabry +5 more
doaj +1 more source
The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cells. [PDF]
PLoS ONE, 2013 The heat shock response (HSR) is a highly conserved molecular response to various types of stresses, including heat shock, during which heat-shock proteins (Hsps) are produced to prevent and repair damages in labile proteins and membranes.
Zohar Bromberg +3 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley +1 more source
Direct proton conductance through the TRPV1 pore and multimerization of TRPV channel subunits
, 2005 0\. Titelblatt und Inhaltsverzeichnis 1\. Einleitung 2\. Zielsetzung 3\. Material und Methoden 4\. Ergebnisse 5\. Diskussion 6\. Zusammenfassung 7\. Referenzen 8\.
Hellwig, Nicole Barbara
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The expression of TRPV channels, prostaglandin E2 and pro-inflammatory cytokines during behavioural fever in fish [PDF]
, 2018 A fever, or increased body temperature, is a symptom of inflammation, which is a complex defence reaction of the organism to pathogenic infections. After pathogens enter the body, immune cells secrete a number of agents, the functions of which stimulate ...
Diego Crespo +23 more
core +1 more source
A functional nuclear localization sequence in the C. elegans TRPV channel OCR-2. [PDF]
PLoS ONE, 2011 The ability to modulate gene expression in response to sensory experience is critical to the normal development and function of the nervous system. Calcium is a key activator of the signal transduction cascades that mediate the process of translating a ...
Meredith J Ezak, Denise M Ferkey
doaj +1 more source
Journal of Oral Biology and Craniofacial Research, 2023 Objectives: Dental pain, which is the main reason for patients consulting dentists, is classified as a public health concern. The study of cellular and molecular mechanisms contributing to pain is a fundamental element for developing new analgesics.
Lilia Jadith Bernal-Cepeda +2 more
doaj +1 more source