Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control
The Journal of Physiology, EarlyView.
Richard J. A. Wilson +1 more
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng +4 more
wiley +1 more source
Iron Oxide Nanozyme for Magnetothermal Activation of ER-TRPV1 Enables Efficient Intravesical Therapy of Bladder Cancer. [PDF]
Int J Mol SciLi G +7 more
europepmc +1 more source
TGF‐β1 Directly Sensitizes Capsaicin‐Sensitive Lung Vagal Neurons to Promote Airway Hypersensitivity
Acta Physiologica, Volume 242, Issue 10, October 2026.ABSTRACT Aim Transforming growth factor‐β1 (TGF‐β1) is a pleiotropic cytokine implicated in the pathogenesis of inflammatory airway diseases such as asthma. Airway hypersensitivity (AHS), arising from sensitization of capsaicin‐sensitive lung vagal (CSLV) afferents, is a hallmark of these airway diseases.
Yueh‐Yin Chen +2 more
wiley +1 more source
Effects of burosumab on macrophage polarization and TRPV1 expression in children with XLH. [PDF]
Endocr ConnectDi Paola A +11 more
europepmc +1 more source
The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation
International Endodontic Journal, Volume 59, Issue 10, Page 2028-2045, October 2026.ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli +3 more
wiley +1 more source
Activation of the G-protein coupled estrogen receptor 1 (GPER1) reduces transient receptor potential vanilloid 1 (TRPV1) activity and human iPSC-derived nociceptive neuron firing. [PDF]
Stem Cell Res TherDräger O +4 more
europepmc +1 more source
Is Capsaicin Effective in Relieving the Symptoms of Burning Mouth Syndrome? A Systematic Review
Journal of Oral Rehabilitation, Volume 53, Issue 10, Page 1985-1996, October 2026.The capsaicin, administered topically or systemically, reduces pain symptoms in patients with Burning Mouth Syndrome (BMS). However, despite consistent clinical improvement, the current evidence is limited and of low certainty, highlighting the need for well‐designed studies to confirm its effectiveness. ABSTRACT Background Burning Mouth Syndrome (BMS)
Ana Paula de Andrade Silva +7 more
wiley +1 more source
Exploring GC-MS-Based Phytochemistry and Network Pharmacology to Elucidate the Multi-Target Therapeutic Potential of Betel Leaf Oil as an Analgesic and Anti-Inflammatory Agent. [PDF]
Biomed ChromatogrParveen S, Yadav DK.
europepmc +1 more source
Early-life cisplatin exposure induces neuroinflammation and chemotherapy-induced neuropathic pain
Disease Models & MechanismsMarlene Da Vitoria Lobo +8 more
doaj +1 more source