Results 171 to 180 of about 37,042 (291)

From Bibliometrics to Preliminary Clinical Evidence: TRP Channel-Mediated Neuroimmune Crosstalk in Temperature-Sensitive Airway Hyperresponsiveness. [PDF]

J Inflamm Res
Wang Y, Zhao Q, Zhang H, Wang L, Fu S, Cheng F, Qi X, Zhu X, Zhang Q, Xu D, Liu M, Zhao C.   +11 more
europepmc   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

LIPUS combined with mild hyperthermia promotes rotator cuff healing via TRPV1/Ca²⁺/CaMKII-driven BACH2 nuclear translocation and inhibition of M1 polarization. [PDF]

J Orthop Translat
Xue X, Lin X, Gao A, Kuati A, Fu H, Cui G, Xu B, Song Q.   +7 more
europepmc   +1 more source

Targeting TRPV1 channels: new perspectives on the mechanisms of analgesia for herpes zoster neuralgia and advances in therapeutic research. [PDF]

Front Cell Infect Microbiol
Zhang Y, Li Y, Xiao N, Wu F.
europepmc   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

Zoledronic acid produces analgesia by inhibiting the transient receptor potential vanilloid 1 (TRPV1) channel. [PDF]

Pain Rep
Carvajal-Zamorano K, Amaya-Rodríguez CA, Gómez Del Campo A, Palacios-Muñoz A, Ardiles NM, Ancatén-González C, Meza RC, Plaza-Briceño W, Segura I, Scala R, Tricarico D, Moya PR, Madrid R, Chávez AE, Latorre R, Castillo K.   +15 more
europepmc   +1 more source

Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1

The Journal of Physiology, EarlyView.
Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang, Pabitra Hriday Patra, Jinquan Yang   +2 more
wiley   +1 more source

A TRPA1-mediated substance P release assay as an <i>in vitro</i> screening tool for airway irritant potential. [PDF]

Front Toxicol
Bedford R, Medhane R, Lawrance J, Hollings M.   +3 more
europepmc   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

TRPV1 Suppresses Microglial Inflammatory Activation to Ameliorate Schizophrenia-Associated Behaviors in Maternal Separation Rats. [PDF]

Schizophr Bull
Chen F, Hao K, Shu C, Xiong Y, Xu R, Huang H, Peng B, Liu Z, Reynolds GP, Wang G, Wang H.   +10 more
europepmc   +1 more source