Results 171 to 180 of about 13,621 (198)

Mechanistic Insights Into How Acupuncture Modulates Host Immunity via the Gut Microbiota‐Macrophage Axis

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
Electroacupuncture at specific acupoints (e.g., ST36, ST25) activates somato‑vagal neural circuits via PROKR2‑expressing sensory fibers. This top‑down signal restructures the gut microenvironment by enriching beneficial symbionts (e.g., Akkermansia muciniphila) and strengthening the intestinal barrier.
Tao Yang, Mei Li, Xiaowen Wu
wiley   +1 more source

“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox

open access: yesNeurourology and Urodynamics, Volume 45, Issue 8, Page 1479-1481, November 2026.
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan   +2 more
wiley   +1 more source

Update of Korean Medicine Clinical Practice Guidelines for Obesity Management: An Evidence‐Based GRADE Approach

open access: yesObesity, Volume 34, Issue 11, Page 2031-2050, November 2026.
ABSTRACT Objective Obesity is a major health challenge associated with multiple chronic diseases. Korean traditional medicine (KM) offers diverse therapeutic approaches for obesity management. This study aims to update the Korean Medicine Clinical Practice Guidelines (KMCPGs) by incorporating recent evidence to improve the effectiveness of KM‐based ...
Soo‐Dam Kim   +16 more
wiley   +1 more source

Phytochemical Profiling and Safety Assessment of Maerua crassifolia Forssk. Aerial Parts Infusion With Pharmacological Validation of Its Analgesic and Anti‐Inflammatory Activities

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
Rich in phenolic compounds, Maerua crassifolia Forssk. aerial parts infusion combines strong antioxidant capacity with a favorable acute safety profile. It produces dose‐dependent analgesic and anti‐inflammatory effects in vivo, approaching reference‐drug activity.
Leila Benazzi   +6 more
wiley   +1 more source

Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation

open access: yesRespirology, Volume 31, Issue 11, Page 1077-1090, November 2026.
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley   +1 more source

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10459-10474, November 2026.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch   +15 more
wiley   +1 more source

A Randomized Controlled Study of an HMWHA‐Containing Mask in Skin Repair Following Fractional CO2 Laser Resurfacing

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 11, November 2026.
ABSTRACT Objective The main objective of this study was to evaluate the overall clinical efficacy of a high‐molecular‐weight hyaluronic acid (HMWHA)‐containing mask in improving skin damage in subjects after ablative fractional laser treatment. Methods Subjects who underwent ablative fractional CO2 laser treatment were randomly assigned to two groups ...
Zongzhou Wu   +7 more
wiley   +1 more source

The Use of Cannabidiol in Cutaneous Wound Healing: A Systematic Review

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Proposed mechanisms by which cannabidiol (CBD) promotes cutaneous wound healing. CBD modulates inflammatory and oxidative pathways, enhances fibroblast migration and proliferation, stimulates collagen deposition and extracellular matrix remodeling, and promotes angiogenesis, collectively contributing to improved tissue repair. ABSTRACT Cutaneous wounds
João Henrique Ferreira França   +7 more
wiley   +1 more source

Beta‐Arrestin‐2 Binds to Nucleolar Organizing Regions With P2X7 Receptor Stimulation and During Cell Division

open access: yesThe FASEB Journal, Volume 40, Issue 19, 15 October 2026.
Beta‐Arrestin‐2 but not Beta‐Arrestin‐1 can accumulate in the nucleolus and come in close contact with the Nucleolar Organizing Regions during two distinct processes: P2X7 receptor stimulation (A) and cell division (B). Both seem to be due to loss of nuclear membrane barrier that keeps Beta‐arrestin‐2 out of the nucleus.
Tuğba Gümüştaş   +4 more
wiley   +1 more source
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Structural Snapshots of TRPV1 Reveal Mechanism of Polymodal Functionality

Cell, 2021
Yifan Cheng, David Julius, Kaihua Zhang
exaly  

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