Results 171 to 180 of about 13,621 (198)
Electroacupuncture at specific acupoints (e.g., ST36, ST25) activates somato‑vagal neural circuits via PROKR2‑expressing sensory fibers. This top‑down signal restructures the gut microenvironment by enriching beneficial symbionts (e.g., Akkermansia muciniphila) and strengthening the intestinal barrier.
Tao Yang, Mei Li, Xiaowen Wu
wiley +1 more source
“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan +2 more
wiley +1 more source
ABSTRACT Objective Obesity is a major health challenge associated with multiple chronic diseases. Korean traditional medicine (KM) offers diverse therapeutic approaches for obesity management. This study aims to update the Korean Medicine Clinical Practice Guidelines (KMCPGs) by incorporating recent evidence to improve the effectiveness of KM‐based ...
Soo‐Dam Kim +16 more
wiley +1 more source
Rich in phenolic compounds, Maerua crassifolia Forssk. aerial parts infusion combines strong antioxidant capacity with a favorable acute safety profile. It produces dose‐dependent analgesic and anti‐inflammatory effects in vivo, approaching reference‐drug activity.
Leila Benazzi +6 more
wiley +1 more source
Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley +1 more source
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch +15 more
wiley +1 more source
ABSTRACT Objective The main objective of this study was to evaluate the overall clinical efficacy of a high‐molecular‐weight hyaluronic acid (HMWHA)‐containing mask in improving skin damage in subjects after ablative fractional laser treatment. Methods Subjects who underwent ablative fractional CO2 laser treatment were randomly assigned to two groups ...
Zongzhou Wu +7 more
wiley +1 more source
The Use of Cannabidiol in Cutaneous Wound Healing: A Systematic Review
Proposed mechanisms by which cannabidiol (CBD) promotes cutaneous wound healing. CBD modulates inflammatory and oxidative pathways, enhances fibroblast migration and proliferation, stimulates collagen deposition and extracellular matrix remodeling, and promotes angiogenesis, collectively contributing to improved tissue repair. ABSTRACT Cutaneous wounds
João Henrique Ferreira França +7 more
wiley +1 more source
Beta‐Arrestin‐2 but not Beta‐Arrestin‐1 can accumulate in the nucleolus and come in close contact with the Nucleolar Organizing Regions during two distinct processes: P2X7 receptor stimulation (A) and cell division (B). Both seem to be due to loss of nuclear membrane barrier that keeps Beta‐arrestin‐2 out of the nucleus.
Tuğba Gümüştaş +4 more
wiley +1 more source
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Structural Snapshots of TRPV1 Reveal Mechanism of Polymodal Functionality
Cell, 2021Yifan Cheng, David Julius, Kaihua Zhang
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