Abstract Left ventricular assist devices have gained traction both as a bridge therapy and as a destination therapy in the management of heart failure. Many of these devices reinstate blood flow in a continuous manner as opposed to the pulsatile flow present in normal physiology.
Tania Warnakulasuriya +2 more
wiley +1 more source
Early-life cisplatin exposure induces neuroinflammation and chemotherapy-induced neuropathic pain
Marlene Da Vitoria Lobo +8 more
doaj +1 more source
Biological fundamental functional units of meridians: mechanosensitive ion channels. [PDF]
Wang Y, Zhou X, He S.
europepmc +1 more source
Physiological mechanisms and therapeutic targets in chronic cough
Abstract Cough is a vital defensive reflex that safeguards the airways; however, it can become maladaptive and pathological. Chronic cough (>8 weeks in duration) affects up to 10% of the global adult population and is associated with considerable health status impairment. The understanding of cough physiology remains limited.
James C. Brown +3 more
wiley +1 more source
Loss of TRPV1 may shift capsaicin response from MAPK-CASC11-MYC protection to mitochondrial apoptosis in glioblastoma U87 cells. [PDF]
Chinreddy SR +7 more
europepmc +1 more source
Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley +1 more source
Capsaicin Receptor TRPV1 Delays Aortic Aging in Atherosclerotic Mice by Inhibiting the ISG15-p53 Pathway. [PDF]
Zhang D +6 more
europepmc +1 more source
Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges
Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley +1 more source
Injectable Poloxamer and Hyaluronic Acid Hydrogel for Sustained Co-Delivery of Dexamethasone and Lidocaine Ameliorates Neuropathic Pain. [PDF]
Liu Y +7 more
europepmc +1 more source
Inhibition of transient receptor potential vanilloid 1 (TRPV1) by a novel selective antagonist for anti-nociceptive effect on inflammatory pain without hyperthermia. [PDF]
Guan J, Zhao C, Zhou Q, Zhu C.
europepmc +1 more source

