Results 51 to 60 of about 3,959 (186)
A Review of the Phytochemistry and Pharmacological Properties of the Genus Arrabidaea
Pharmaceuticals, 2022 The genus Arrabidaea, consisting of ~170 species, belongs to the family Bignoniaceae, distributed around the Neotropics and temperate zone. The center of diversity of the family is in Brazil, where 56 genera and about 340 species exist.
Jessyane Rodrigues do Nascimento +9 more
doaj +1 more source
Trypanocidal drugs: mechanisms, resistance and new targets. [PDF]
, 2009 The protozoan parasites Trypanosoma brucei and Trypanosoma cruzi are the causative agents of African trypanosomiasis and Chagas disease, respectively. These are debilitating infections that exert a considerable health burden on some of the poorest people
Wilkinson, SR +4 more
core +1 more source
In Vitro Evaluation of Arylsulfonamide Derivatives against Trypanosoma cruzi
Drugs and Drug Candidates, 2023 Chagas disease is caused by the parasite protozoan Trypanosoma cruzi (T. cruzi) and affects millions of people in over 21 countries in around the world.
Policarpo Ademar Sales Junior +2 more
doaj +1 more source
Trypanocidal activity of methanol extracts of the hemolymph of Sarcophaga argyrostoma larva against Trypanosoma evansi infected mice [PDF]
Veterinary World, 2020 Background and Aim: Many natural products worldwide are used for medicinal purposes. Various insect-isolated compounds were investigated in pursuit of new therapeutic agents.
Doaa S. Farghaly, Al-Shaimaa M. Sadek
doaj +1 more source
Flavour and Fragrance Journal, Volume 41, Issue 4, Page 935-942, July 2026.The samples were fungicidal against Candida, with MICs ranging from 62.5 to 250 μg/mL, and fungistatic against Penicillium adametzii, Aspergillus flavus and A. niger, with MICs of 1000 μg/mL. The volatile oils of Piper aduncum and Piper marginatum reduced the viability of MDA‐MB231 cells.
Midiã R. Oliveira +11 more
wiley +1 more source
Molecules, 2022 A method was developed for the rapid and quantitative analysis of 30 veterinary drugs belonging to 17 classes (amphenicols (1), anthelmintics (1), cephalosporins (4), coccidiostats (1), lincosamides (1), macrolide (1), nitroimidazole (1), penicillins (3),
Sunyeong Jang +8 more
doaj +1 more source
Trypanosoma cruzi: analysis of two different strains after piplartine treatment
Brazilian Journal of Infectious Diseases, 2018 The hemoflagellate protozoan, Trypanosoma cruzi, mainly transmitted by triatomine insects through blood transfusion or from mother-to-child, causes Chagas' disease.
Gabriela Alves Licursi Vieira +7 more
doaj +3 more sources
Cedrela fissilis Vell. Inner Bark: LC–MS/MS‐Based Chemical Profiling and Toxicological Effects
Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.ABSTRACT Investigating the mechanistic toxicity of plant extracts is essential for safety assessment. The predictive toxicological effects of Cedrela fissilis were evaluated, and LC–MS/MS‐based chemical profiling was performed. The hydroethanolic extract (HeECf) and ethyl acetate (EA) fraction were assessed in multimodel systems with different levels ...
Thainá Pereira da Silva Cabral +10 more
wiley +1 more source
Pharmaceuticals, 2021 The neglected infection known as Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, results in more than 7000 deaths per year, with an increasing number of cases in non-endemic areas such as Europe or the United States.
Carlos J. Bethencourt-Estrella +8 more
doaj +1 more source
Intravenous liposomal benznidazole as trypanocidal agent: increasing drug delivery to liver is not enough [PDF]
International Journal of Pharmaceutics, 2004 With the aim of investigating if delivery of benznidazole (BNZ) to liver could be increased by incorporating the drug in multilamellar liposomes, single bolus of free BNZ or liposomal BNZ formulations (MLV-BNZ) composed of HSPC:DSPG:Chol 2:1:2 (mol/mol/mol) at 0.7% (w/w) drug/total lipid ratio, were injected by intramuscular (i.m.), subcutaneous (s.c.)
M J, Morilla +5 more
openaire +2 more sources