Results 11 to 20 of about 167,118 (269)

Regulation of gene expression in trypanosomatids: living with polycistronic transcription [PDF]

Open Biology, 2019
In trypanosomes, RNA polymerase II transcription is polycistronic and individual mRNAs are excised by trans-splicing and polyadenylation. The lack of individual gene transcription control is compensated by control of mRNA processing, translation and ...
Christine Clayton
doaj   +1 more source

Intrabody-Induced Cell Death by Targeting the T. brucei Cytoskeletal Protein TbBILBO1

Microbiology Spectrum, 2021
Trypanosoma brucei belongs to a genus of protists that cause life-threatening and economically important diseases of human and animal populations in Sub-Saharan Africa. T.
Christine E. Broster Reix, Miharisoa Rijatiana Ramanantsalama, Carmelo Di Primo, Laëtitia Minder, Mélanie Bonhivers, Denis Dacheux, Derrick R. Robinson   +6 more
doaj   +1 more source

Tsetse fly ecology and risk of transmission of African trypanosomes related to a protected forest area at a military base in the city of Abidjan, Côte d’Ivoire

Parasite, 2023
African trypanosomoses, whose pathogens are transmitted by tsetse flies, are a threat to animal and human health. Tsetse flies observed at the military base of the French Forces in Côte d’Ivoire (FFCI base) were probably involved in the infection and ...
Konan Yao Jean Rodrigue, Berté Djakaridja, Ta Bi Tra Dieudonné, Demoncheaux Jean-Paul, Sauzet Sylvie, Watier-Grillot Stéphanie, Kouadio Koffi Alain De Marie, N’dri Louis, Coulibaly Bamoro, Solano Philippe, Ravel Sophie, Ségard Adeline, Kaba Dramane, De Meeûs Thierry, Djohan Vincent, Jamonneau Vincent   +15 more
doaj   +1 more source

Equine trypanosomiasis, a systematic review: Disease management. [PDF]

Equine Vet J
Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To answer the study question: In equines what are the effects of disease management of trypanosomiasis on disease severity (individual level) and disease prevalence (population level) compared to no intervention? Study Design Systematic review.
Raftery AG, Gummery L, Garcia K, Mohite D, Capewell P, Sutton D.   +5 more
europepmc   +2 more sources

Ubiquitination and the Proteasome as Drug Targets in Trypanosomatid Diseases

Frontiers in Chemistry, 2021
The eukaryotic pathogens Trypanosoma brucei, Trypanosoma cruzi and Leishmania are responsible for debilitating diseases that affect millions of people worldwide.
Marie-José Bijlmakers
doaj   +1 more source

Protective immunity against Trypanosoma cruzi [PDF]

, 2009
Upon infection, Trypanosoma cruzi triggers a strong immune response that has both protective and pathological consequences. In this work, several important questions regarding protective immunity are reviewed.
Basombrío, Miguel Ángel Manuel, Padilla, Ángel Marcelo, Parodi Ramoneda, Cecilia María   +2 more
core   +1 more source

African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]

, 2017
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar, Alampour-Rajabi, Alirol, Allman, Authie, Authié, Auty, Baker, Balber, Banks, Barry, Barry, Berthier, Beschin, Beschin, Blom-Potar, Bockstal, Bockstal, Boller, Bonnet, Borst, Bosschaerts, Boulange, Bouyer, Brun, Brun, Bucheton, Calandra, Capewell, Chamond, Claes, Cnops, Cnops, Cnops, Cnops, Coller, Dagenais, Darji, De Muylder, De Trez, Delafosse, Delespaux, Desquesnes, Devine, Disease, Drennan, Dubois, Duszenko, Engstler, Fenn, Ferrante, Field, Figarella, Franco, Frenkel, Gilbert, Giordani, Gomez-Rodriguez, Graham, Graham, Haanstra, Hall, Hasker, Hemphill, Holland, Holland, Holt, Jamonneau, Jarvinen, Jones, Keitany, Kennedy, Kennedy, Klasen, Kondo, Kroubi, Kuriakose, La Greca, La Greca, Lalmanach, Lanca, Lebien, Lejon, Lejon, Leng, MacGregor, MacGregor, MacLean, MacLean, Magez, Magez, Magez, Mansfield, McGettrick, Mekori, Millar, Mogk, Mony, Morrison, Morrison, Morrison, Mulindwa, Mårtensson, Naessens, Naula, Ng, Nutt, Obishakin, Odongo, Onyilagha, Ooi, Ooi, Osório, O’Gorman, Paulnock, Pays, Peacock, Priotto, Radwanska, Radwanska, Reth, Rico, Rodgers, Rotureau, Ruiz-Postigo, Salmon, Schwede, Schwede, Seed, Sharpe, Sileghem, Sileghem, Simarro, Simarro, Simarro, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Swallow, Takeya, Taylor, Taylor, Taylor, Telleria, Tiberti, Trindade, Unciti-Broceta, Uzonna, Uzonna, Van Den Abbeele, Vassella, Welburn, Welburn, Wellde, Wenzler, Willert, Yaro   +160 more
core   +1 more source

Highly Localized Enrichment of Trypanosoma brucei Parasites Using Dielectrophoresis

Micromachines, 2020
Human African trypanosomiasis (HAT), also known as sleeping sickness, is a vector-borne neglected tropical disease endemic to rural sub-Saharan Africa.
Devin Keck, Callie Stuart, Josie Duncan, Emily Gullette, Rodrigo Martinez-Duarte   +4 more
doaj   +1 more source

Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea [PDF]

Open Biology, 2020
Phosphoglycerate kinase (PGK) is a glycolytic enzyme that is well conserved among the three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses one of the two ATP-producing reactions in the glycolytic pathway, through the ...
Maura Rojas-Pirela, Diego Andrade-Alviárez, Verónica Rojas, Ulrike Kemmerling, Ana J. Cáceres, Paul A. Michels, Juan Luis Concepción, Wilfredo Quiñones   +7 more
doaj   +1 more source

Bhalin, an Essential Cytoskeleton-Associated Protein of Trypanosoma brucei Linking TbBILBO1 of the Flagellar Pocket Collar with the Hook Complex

Microorganisms, 2021
Background: In most trypanosomes, endo and exocytosis only occur at a unique organelle called the flagellar pocket (FP) and the flagellum exits the cell via the FP.
Christine E. Broster Reix, Célia Florimond, Anne Cayrel, Amélie Mailhé, Corentin Agnero-Rigot, Nicolas Landrein, Denis Dacheux, Katharina Havlicek, Mélanie Bonhivers, Brooke Morriswood, Derrick R. Robinson   +10 more
doaj   +1 more source