Results 31 to 40 of about 75,849 (239)
Frequency and diversity of trypanosomes in sheep and goats from Mongo County in South Gabon, Central Africa [PDF]
Veterinary World, 2020 Background and Aim: Trypanosomosis is a major impediment to livestock farming in sub-Saharan Africa. It is a vector-borne disease caused by several species of protozoan parasites, namely, trypanosomes. The present study aimed to identify the diversity of
Gael Darren Maganga +6 more
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Broadening the spectrum of ivermectin: Its effect on Trypanosoma cruzi and related trypanosomatids
Frontiers in Cellular and Infection Microbiology, 2022 Chagas disease is an endemic American parasitosis, caused by Trypanosoma cruzi. The current therapies, benznidazole (BZN) and nifurtimox (NFX), show limited efficacy and multiple side effects. Thus, there is a need to develop new trypanocidal strategies.
Laura Fraccaroli +6 more
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Trypanosoma (Duttonefla) vivax
Parasitology Today, 1987 Although Trypanosoma vivax was first discovered in 1905 (Ref. 1), the fact that most stocks of this parasite are restricted to ruminant hosts has retarded investigation of this species compared with the experimentally more amenable T. brucei and T. congolense. The veterinary importance of T. vivax (Box 1) and a recent report suggesting that T.
Gardiner, Peter R., Wilson, A.J.
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Unexpected plasticity in the life cycle of Trypanosoma brucei
eLife, 2021 African trypanosomes cause sleeping sickness in humans and nagana in cattle. These unicellular parasites are transmitted by the bloodsucking tsetse fly. In the mammalian host’s circulation, proliferating slender stage cells differentiate into cell cycle ...
Sarah Schuster +7 more
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The exosome of Trypanosoma brucei [PDF]
The EMBO Journal, 2001 The yeast exosome is a complex of at least 10 essential 3'-5' riboexonucleases which is involved in 3'-processing of many RNA species. An exosome-like complex has been found or predicted to exist in other eukaryotes but not in Escherichia coli. The unicellular parasite Trypanosoma brucei diverged very early in eukaryotic evolution.
Antonio M. Estévez +2 more
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On The Cultivation Of Trypanosoma Brucei [PDF]
Journal of Infectious Diseases, 1904 n ...
Novy, F. G., McNeal, W. J.
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Novel Trypanocidal Inhibitors that Block Glycosome Biogenesis by Targeting PEX3–PEX19 Interaction
Frontiers in Cell and Developmental Biology, 2021 Human pathogenic trypanosomatid parasites harbor a unique form of peroxisomes termed glycosomes that are essential for parasite viability. We and others previously identified and characterized the essential Trypanosoma brucei ortholog TbPEX3, which is ...
Mengqiao Li +11 more
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Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Advanced Science, EarlyView.Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu +13 more
wiley +1 more source
Advanced Science, EarlyView.This study engineers Yarrowia lipolytica to produce succinic acid (SA) from lignocellulosic biomass. Adaptive evolution and multi‐omics analysis identify regulators that alleviate xylose metabolic disorder. Multi‐copy integration of xylose metabolic genes resolves redox imbalances from a futile fatty acid cycle, producing high‐titer SA from corn stover
Yutao Zhong +7 more
wiley +1 more source
Prevalence of Haemoparasites among Blood Donors in Calabar, Nigeria
Medical Laboratory Journal, 2021 Background and objectives: Voluntary blood donation is the main source of blood and its components globally. Blood transfusion is essential for management of various diseases but remains as one of the most important causes of disease transmission.
Paul Inyang-Etoh +3 more
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