Results 11 to 20 of about 101,216 (253)

The system of genetic exchange in Trypanosoma brucei and other trypanosomatids [PDF]

open access: yes, 2007
In this chapter, we discuss our current understanding of the systems of genetic exchange in trypanosomatids and the im-pact the recent genome projects have had on this area of research.
Turner, C.M.R., Tait, A., MacLeod, A.
core   +8 more sources

Molecular detection of Trypanosoma species in sheep and goats in Mosul city [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2022
In this study, we examined blood samples of 385 sheep and goats of different ages, sexes, and sources under routine microscopic examination of the blood smear (wet, thin, thick, buffy coat layer smears) to detect Trypanosoma. Results show that 81 samples
Marwa S. Mahmood, Wasan A. Alobaidii
doaj   +1 more source

Comparative SILAC proteomic analysis of Trypanosoma brucei bloodstream and procyclic lifecycle stages [PDF]

open access: yes, 2012
The protozoan parasite Trypanosoma brucei has a complex digenetic lifecycle between a mammalian host and an insect vector, and adaption of its proteome between lifecycle stages is essential to its survival and virulence. We have optimized a procedure for
Urbaniak, Michael   +2 more
core   +5 more sources

Tracking autophagy during proliferation and differentiation of Trypanosoma brucei [PDF]

open access: yes, 2014
Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Mottram, Jeremy   +3 more
core   +5 more sources

PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes

open access: yeseLife, 2023
African trypanosomes evade host immune clearance by antigenic variation, causing persistent infections in humans and animals. These parasites express a homogeneous surface coat of variant surface glycoproteins (VSGs).
Abdoulie O Touray   +6 more
doaj   +1 more source

Tag Thy Neighbour: Nanometre-Scale Insights Into Kinetoplastid Parasites With Proximity Dependent Biotinylation

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Proximity labelling is a powerful and rapidly developing technology for exploring the interaction space and molecular environment of a protein of interest at the nanometre scale.
Vincent Geoghegan   +2 more
doaj   +1 more source

Chagas Cardiomyopathy: From Romaña Sign to Heart Failure and Sudden Cardiac Death

open access: yesPathogens, 2021
Despite nearly a century of research and accounting for the highest disease burden of any parasitic disease in the Western Hemisphere, Chagas disease (CD) is still a challenging diagnosis, primarily due to its poor recognition outside of Latin America ...
Antonia Pino-Marín   +9 more
doaj   +1 more source

Detection of Blood Parasites in Fish

open access: yesJournal of Pure and Applied Microbiology, 2023
Fish are often infected with different blood protozoa of the genera Babesiosoma, Trypanosoma, and Hemogrigarina. These blood parasites match the genera which infect the blood of mammals.
Nadia Sultan Alhayali   +2 more
doaj   +1 more source

Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea [PDF]

open access: yesOpen Biology, 2020
Phosphoglycerate kinase (PGK) is a glycolytic enzyme that is well conserved among the three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses one of the two ATP-producing reactions in the glycolytic pathway, through the ...
Maura Rojas-Pirela   +7 more
doaj   +1 more source

Bhalin, an Essential Cytoskeleton-Associated Protein of Trypanosoma brucei Linking TbBILBO1 of the Flagellar Pocket Collar with the Hook Complex

open access: yesMicroorganisms, 2021
Background: In most trypanosomes, endo and exocytosis only occur at a unique organelle called the flagellar pocket (FP) and the flagellum exits the cell via the FP.
Christine E. Broster Reix   +10 more
doaj   +1 more source

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